| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxycycline (monohydrate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxycycline (monohydrate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | 0.0726151 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0686194 |
| CCNL1 | cyclin L1 | 0.0553691 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0516542 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0494618 |
| PLAU | plasminogen activator, urokinase | 0.0483089 |
| NUP58 | nucleoporin 58 | 0.0439958 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0429557 |
| TGM2 | transglutaminase 2 | 0.0426905 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.04223 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0414627 |
| HLA-A | major histocompatibility complex, class I, A | 0.0395802 |
| SMAD3 | SMAD family member 3 | 0.039413 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0381725 |
| MUC4 | mucin 4, cell surface associated | 0.0370047 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.036638 |
| DST | dystonin | 0.0365424 |
| FAM3C | family with sequence similarity 3, member C | 0.0360681 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.036043 |
| HLA-B | major histocompatibility complex, class I, B | 0.0351414 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0342418 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0338139 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0330869 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0327125 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0322739 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0320946 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0317476 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0309556 |
| MT2A | metallothionein 2A | 0.0308259 |
| FOSL1 | FOS-like antigen 1 | 0.0307727 |
| DUSP5 | dual specificity phosphatase 5 | 0.0307289 |
| NDRG1 | N-myc downstream regulated 1 | 0.0300866 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0297907 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0295282 |
| KLF6 | Kruppel-like factor 6 | 0.02928 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0290409 |
| ACTN4 | actinin, alpha 4 | 0.0289788 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0289488 |
| FLNA | filamin A, alpha | 0.02875 |
| VMP1 | vacuole membrane protein 1 | 0.0283996 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0277507 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.027719 |
| PEG10 | paternally expressed 10 | 0.0268909 |
| PKM | pyruvate kinase, muscle | 0.0264642 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0262814 |
| DENND4A | DENN/MADD domain containing 4A | 0.0261797 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0261681 |
| ERBIN | erbb2 interacting protein | 0.0260215 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.0259858 |
| PCBP2 | poly(rC) binding protein 2 | 0.0258826 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0256825 |
| AGRN | agrin | 0.0255155 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0253807 |
| MYO6 | myosin VI | 0.0251866 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0251504 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0244656 |
| MYOF | myoferlin | 0.0243442 |
| ITGB8 | integrin, beta 8 | 0.0237718 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0236214 |
| AXL | AXL receptor tyrosine kinase | 0.0236055 |
| CLDN4 | claudin 4 | 0.0234352 |
| EGR1 | early growth response 1 | 0.0233282 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0233199 |
| NRG3 | neuregulin 3 | 0.0231374 |
| DIAPH1 | diaphanous-related formin 1 | 0.0228668 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0227385 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0226975 |
| TJP1 | tight junction protein 1 | 0.021721 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0216412 |
| VEGFA | vascular endothelial growth factor A | 0.0215702 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0214843 |
| MATR3 | matrin 3 | 0.0214085 |
| TPM1 | tropomyosin 1 (alpha) | 0.0213451 |
| RBM47 | RNA binding motif protein 47 | 0.0212487 |
| RCOR1 | REST corepressor 1 | 0.0209569 |
| RASAL2 | RAS protein activator like 2 | 0.0209355 |
| TAPBP | TAP binding protein (tapasin) | 0.0208608 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0208365 |
| CASC3 | cancer susceptibility candidate 3 | 0.0207528 |
| USP12 | ubiquitin specific peptidase 12 | 0.020654 |
| NCOR2 | nuclear receptor corepressor 2 | 0.020584 |
| WDR43 | WD repeat domain 43 | 0.0203103 |
| MCL1 | myeloid cell leukemia 1 | 0.0201429 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0200851 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0199729 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0196908 |
| HDAC9 | histone deacetylase 9 | 0.0195693 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0195436 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0194825 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0194673 |
| PTK2 | protein tyrosine kinase 2 | 0.0194152 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0193646 |
| LAMB1 | laminin, beta 1 | 0.0193579 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0193103 |
| MKI67 | marker of proliferation Ki-67 | 0.019154 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0189627 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0188385 |
| FOSL2 | FOS-like antigen 2 | 0.01876 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0187474 |
| SLK | STE20-like kinase | 0.0187229 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.284396 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.224829 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.199288 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.112631 |
| MMP7 | matrix metallopeptidase 7 | -0.105809 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0922683 |
| H1-0 | H1.0 linker histone | -0.0866738 |
| AHNAK | AHNAK nucleoprotein | -0.0863463 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0851825 |
| ANXA2 | annexin A2 | -0.0833324 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0805061 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0780436 |
| UBC | ubiquitin C | -0.0712364 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0712261 |
| PTMA | prothymosin, alpha | -0.0690351 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.068884 |
| FTL | ferritin, light polypeptide | -0.06586 |
| VIM | vimentin | -0.0617236 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0616393 |
| MT1X | metallothionein 1X | -0.0584251 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.058391 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0582697 |
| PARD3 | par-3 family cell polarity regulator | -0.0578472 |
| CANX | calnexin | -0.0575231 |
| TMSB4X | thymosin beta 4, X-linked | -0.0571644 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0565604 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0534623 |
| RPL19 | ribosomal protein L19 | -0.0510641 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0508919 |
| KRT19 | keratin 19, type I | -0.050685 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0497076 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0489092 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0484246 |
| S100A6 | S100 calcium binding protein A6 | -0.047897 |
| TMSB10 | thymosin beta 10 | -0.0464729 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0457079 |
| CCNY | cyclin Y | -0.0449596 |
| FAM13A | family with sequence similarity 13, member A | -0.0449355 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0437716 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0415668 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0408354 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0406706 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.039814 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0390235 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0389497 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0387495 |
| OGA | O-GlcNAcase | -0.037937 |
| CSTB | cystatin B (stefin B) | -0.0377816 |
| STC1 | stanniocalcin 1 | -0.0374178 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0370178 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0365567 |
| RPS24 | ribosomal protein S24 | -0.0362029 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0360327 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0358956 |
| RPLP0 | ribosomal protein, large, P0 | -0.03554 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0336436 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0331607 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0329818 |
| TMEM263 | transmembrane protein 263 | -0.0328662 |
| RPLP1 | ribosomal protein, large, P1 | -0.032843 |
| RPS6 | ribosomal protein S6 | -0.0322276 |
| RBM39 | RNA binding motif protein 39 | -0.0320035 |
| TOP1 | topoisomerase (DNA) I | -0.0319395 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0315926 |
| SP100 | SP100 nuclear antigen | -0.0313012 |
| RPL23 | ribosomal protein L23 | -0.0310917 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0310395 |
| LMO7 | LIM domain 7 | -0.0310276 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0298486 |
| RPS8 | ribosomal protein S8 | -0.0295618 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0295367 |
| S100A10 | S100 calcium binding protein A10 | -0.0289032 |
| DSG2 | desmoglein 2 | -0.0288035 |
| FNBP1L | formin binding protein 1-like | -0.0287685 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0282949 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0282592 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0280959 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.02801 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0278754 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.027541 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0272343 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0268217 |
| ANXA1 | annexin A1 | -0.0267311 |
| ARF1 | ADP-ribosylation factor 1 | -0.0267097 |
| GNAS | GNAS complex locus | -0.0264218 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.0262651 |
| TXNIP | thioredoxin interacting protein | -0.0262497 |
| ATP11B | ATPase, class VI, type 11B | -0.0257918 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0250151 |
| RPL34 | ribosomal protein L34 | -0.0245569 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0243802 |
| TMEM87A | transmembrane protein 87A | -0.0243252 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0242741 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0239465 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0237504 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0229858 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0227664 |
| DTNA | dystrobrevin, alpha | -0.0227616 |
| RLF | rearranged L-myc fusion | -0.022585 |
| ENO1 | enolase 1, (alpha) | -0.0225377 |
