| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxycycline (monohydrate) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxycycline (monohydrate)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.143041 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.135638 |
| FNDC3B | fibronectin type III domain containing 3B | 0.120912 |
| FTL | ferritin, light polypeptide | 0.0898327 |
| NDRG1 | N-myc downstream regulated 1 | 0.0841095 |
| STC1 | stanniocalcin 1 | 0.0716454 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0711789 |
| ATP13A3 | ATPase type 13A3 | 0.0666303 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0654119 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0626995 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0604284 |
| COG5 | component of oligomeric golgi complex 5 | 0.058367 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.055765 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0532869 |
| GOLGA4 | golgin A4 | 0.0522886 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0501935 |
| INHBA | inhibin, beta A | 0.0496981 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0465731 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0452054 |
| HELZ | helicase with zinc finger | 0.0446912 |
| EGFR | epidermal growth factor receptor | 0.0445792 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0443742 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0442224 |
| SMAD3 | SMAD family member 3 | 0.0438575 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0438388 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0429985 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0417625 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0411908 |
| CLTC | clathrin, heavy chain (Hc) | 0.0407306 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.04026 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0398583 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0397314 |
| MSN | moesin | 0.0387778 |
| RNF216 | ring finger protein 216 | 0.0381264 |
| SNX13 | sorting nexin 13 | 0.0376639 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0375405 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0367392 |
| SETD5 | SET domain containing 5 | 0.0365683 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0359454 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0359201 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0352382 |
| SRP54 | signal recognition particle 54kDa | 0.0345323 |
| LRRC49 | leucine rich repeat containing 49 | 0.034026 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0335775 |
| GLIS3 | GLIS family zinc finger 3 | 0.0332729 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0328717 |
| GPR107 | G protein-coupled receptor 107 | 0.0326242 |
| CADM1 | cell adhesion molecule 1 | 0.032215 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0322089 |
| FAM13A | family with sequence similarity 13, member A | 0.0321002 |
| SUCO | SUN domain containing ossification factor | 0.0307661 |
| METTL15 | methyltransferase like 15 | 0.0300265 |
| ZNF841 | zinc finger protein 841 | 0.0300209 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0298493 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0297946 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0294945 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0294165 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.029051 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0289931 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.028902 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0288989 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0288479 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0288171 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0286589 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0286275 |
| ANXA5 | annexin A5 | 0.0284785 |
| RTN4 | reticulon 4 | 0.0284162 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0283708 |
| ZNF292 | zinc finger protein 292 | 0.0277383 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0274654 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0271027 |
| TXNIP | thioredoxin interacting protein | 0.026827 |
| TMEM39A | transmembrane protein 39A | 0.026821 |
| ZNF160 | zinc finger protein 160 | 0.0268066 |
| FAM219A | family with sequence similarity 219, member A | 0.0267004 |
| NCKAP1 | NCK-associated protein 1 | 0.0266185 |
| TPM3 | tropomyosin 3 | 0.0265591 |
| ETNK1 | ethanolamine kinase 1 | 0.0265039 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0264151 |
| TMEM41B | transmembrane protein 41B | 0.0262954 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0261268 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0260263 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0259011 |
| TMED7 | transmembrane emp24 protein transport domain containing 7 | 0.0258823 |
| TFG | TRK-fused gene | 0.025879 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0256118 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0253473 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0252223 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0251016 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0248775 |
| OGA | O-GlcNAcase | 0.0245211 |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing | 0.024492 |
| RLF | rearranged L-myc fusion | 0.0243051 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0242987 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0242794 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0241953 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.024116 |
| URI1 | URI1, prefoldin-like chaperone | 0.0240906 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0240336 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0239487 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.230599 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.201525 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.138069 |
| GRB10 | growth factor receptor-bound protein 10 | -0.124234 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.120447 |
| FN1 | fibronectin 1 | -0.115065 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.111187 |
| HLA-B | major histocompatibility complex, class I, B | -0.105972 |
| TMSB10 | thymosin beta 10 | -0.10162 |
| VIM | vimentin | -0.0806117 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0753779 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0721585 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0707731 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0604723 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0586315 |
| NLGN1 | neuroligin 1 | -0.0574735 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0573765 |
| B2M | beta-2-microglobulin | -0.0570743 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0553057 |
| DST | dystonin | -0.0541596 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0535677 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0534775 |
| PRSS23 | protease, serine, 23 | -0.0531243 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0508451 |
| RIGI | RNA sensor RIG-I | -0.0507555 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0502752 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0492227 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0490827 |
| HLA-A | major histocompatibility complex, class I, A | -0.0490158 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0479669 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0464518 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0454611 |
| VCL | vinculin | -0.0445872 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0441253 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0440821 |
| FUS | FUS RNA binding protein | -0.042207 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0421236 |
| AHNAK | AHNAK nucleoprotein | -0.0403458 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.039712 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0366269 |
| IGF2 | insulin-like growth factor 2 | -0.0363737 |
| INTS6 | integrator complex subunit 6 | -0.0362975 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0359621 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0355299 |
| FSTL1 | follistatin-like 1 | -0.0354446 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0352028 |
| GLCCI1 | glucocorticoid induced 1 | -0.0351508 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0350464 |
| ASPH | aspartate beta-hydroxylase | -0.0347471 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0346399 |
| COL5A1 | collagen, type V, alpha 1 | -0.0344494 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0341381 |
| CD44 | CD44 molecule (Indian blood group) | -0.0331551 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0329018 |
| ZNF804A | zinc finger protein 804A | -0.0328344 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0327091 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0325078 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0321434 |
| DGKI | diacylglycerol kinase, iota | -0.0316533 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0311003 |
| LRRC23 | leucine rich repeat containing 23 | -0.0309981 |
| FBXO11 | F-box protein 11 | -0.030905 |
| NAV1 | neuron navigator 1 | -0.030661 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0306134 |
| ACTG1 | actin gamma 1 | -0.0304804 |
| TENM3 | teneurin transmembrane protein 3 | -0.0302684 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0302239 |
| RPS13 | ribosomal protein S13 | -0.0297831 |
| SQSTM1 | sequestosome 1 | -0.0297678 |
| KYNU | kynureninase | -0.0287514 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0286411 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0286078 |
| WWOX | WW domain containing oxidoreductase | -0.0285657 |
| S100A10 | S100 calcium binding protein A10 | -0.0285588 |
| RPL31 | ribosomal protein L31 | -0.0285318 |
| AEBP2 | AE binding protein 2 | -0.0283607 |
| PTMA | prothymosin, alpha | -0.0280669 |
| EHBP1 | EH domain binding protein 1 | -0.0278842 |
| PXDN | peroxidasin | -0.0274157 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0273904 |
| TPTE | transmembrane phosphatase with tensin homology | -0.0273856 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0272935 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0270974 |
| SP100 | SP100 nuclear antigen | -0.0270164 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0266414 |
| SEPTIN9 | septin 9 | -0.026019 |
| DIAPH2 | diaphanous-related formin 2 | -0.0258807 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0257937 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0257847 |
| RAD51B | RAD51 paralog B | -0.025778 |
| PGK1 | phosphoglycerate kinase 1 | -0.0257331 |
| CEP128 | centrosomal protein 128kDa | -0.0255706 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0255608 |
| RRM2 | ribonucleotide reductase M2 | -0.0255565 |
| HIP1 | huntingtin interacting protein 1 | -0.0254862 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0250509 |
| HLA-C | major histocompatibility complex, class I, C | -0.0247309 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0246151 |
| CEP112 | centrosomal protein 112kDa | -0.0245767 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0242148 |
