| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxycycline (monohydrate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxycycline (monohydrate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | 0.207286 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.112602 |
| MT2A | metallothionein 2A | 0.10609 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.104988 |
| ATP13A3 | ATPase type 13A3 | 0.100012 |
| FN1 | fibronectin 1 | 0.087579 |
| FTL | ferritin, light polypeptide | 0.0870466 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0803232 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0773958 |
| TMSB10 | thymosin beta 10 | 0.0763647 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0751196 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0748489 |
| PTK2 | protein tyrosine kinase 2 | 0.0737788 |
| RPL35A | ribosomal protein L35a | 0.0629438 |
| RPLP1 | ribosomal protein, large, P1 | 0.0611782 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0508719 |
| MT1X | metallothionein 1X | 0.0496901 |
| THOC2 | THO complex 2 | 0.0488472 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0487588 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.047147 |
| HLA-A | major histocompatibility complex, class I, A | 0.0460808 |
| CALR | calreticulin | 0.0447518 |
| FLNB | filamin B, beta | 0.0440606 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0432691 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0425749 |
| DIAPH3 | diaphanous-related formin 3 | 0.0415752 |
| TMEM178B | transmembrane protein 178B | 0.0404206 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0393934 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0386603 |
| ZXDC | ZXD family zinc finger C | 0.0385742 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0381964 |
| CDC27 | cell division cycle 27 | 0.0379016 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0375952 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0368507 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0361606 |
| PRELID2 | PRELI domain containing 2 | 0.0358476 |
| DEK | DEK proto-oncogene | 0.0354999 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.035364 |
| PGK1 | phosphoglycerate kinase 1 | 0.0352195 |
| KRT8 | keratin 8, type II | 0.0350939 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0342935 |
| RPS16 | ribosomal protein S16 | 0.0337491 |
| OGA | O-GlcNAcase | 0.0336134 |
| RPL8 | ribosomal protein L8 | 0.0330652 |
| RPS23 | ribosomal protein S23 | 0.0329842 |
| SLC30A7 | solute carrier family 30 (zinc transporter), member 7 | 0.0326704 |
| RPL32 | ribosomal protein L32 | 0.032001 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0319768 |
| COL5A1 | collagen, type V, alpha 1 | 0.0318489 |
| GLIS3 | GLIS family zinc finger 3 | 0.0317388 |
| ACTN4 | actinin, alpha 4 | 0.0315142 |
| MAP4 | microtubule-associated protein 4 | 0.031336 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0311372 |
| HLA-B | major histocompatibility complex, class I, B | 0.0310682 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0303126 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0300189 |
| PLCB4 | phospholipase C, beta 4 | 0.0298746 |
| FOXP1 | forkhead box P1 | 0.0297076 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0295847 |
| RPS24 | ribosomal protein S24 | 0.0294321 |
| RPLP2 | ribosomal protein, large, P2 | 0.0291612 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0291516 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0289664 |
| VEGFC | vascular endothelial growth factor C | 0.0287157 |
| RPL37 | ribosomal protein L37 | 0.0283594 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0283588 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0281448 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0278173 |
| PODXL | podocalyxin-like | 0.027737 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.027624 |
| JMJD1C | jumonji domain containing 1C | 0.0273696 |
| DIAPH2 | diaphanous-related formin 2 | 0.027274 |
| TXNRD1 | thioredoxin reductase 1 | 0.0269648 |
| KLF12 | Kruppel-like factor 12 | 0.026956 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0269176 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.026825 |
| S100A10 | S100 calcium binding protein A10 | 0.0266239 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.026564 |
| OXR1 | oxidation resistance 1 | 0.0265285 |
| CTSD | cathepsin D | 0.0263084 |
| ZNF804A | zinc finger protein 804A | 0.0261887 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0258811 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0258034 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.02571 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0255227 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | 0.0253441 |
| RIGI | RNA sensor RIG-I | 0.0251667 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0249828 |
| RPL34 | ribosomal protein L34 | 0.0245857 |
| RHEB | Ras homolog enriched in brain | 0.024336 |
| SNX4 | sorting nexin 4 | 0.0240661 |
| LASP1 | LIM and SH3 protein 1 | 0.0239447 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.023855 |
| MED13 | mediator complex subunit 13 | 0.0238309 |
| TENM3 | teneurin transmembrane protein 3 | 0.0238083 |
| ACTG1 | actin gamma 1 | 0.0237339 |
| RPS19 | ribosomal protein S19 | 0.0236884 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0236006 |
| RPL23 | ribosomal protein L23 | 0.0235913 |
| VGLL3 | vestigial-like family member 3 | 0.0235285 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.153805 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.14884 |
| NDRG1 | N-myc downstream regulated 1 | -0.111958 |
| CANX | calnexin | -0.106921 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0916147 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0886102 |
| GOLGB1 | golgin B1 | -0.0865061 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0753394 |
| RAI14 | retinoic acid induced 14 | -0.0742325 |
| SET | SET nuclear proto-oncogene | -0.074144 |
| CD44 | CD44 molecule (Indian blood group) | -0.0739828 |
| ADM | adrenomedullin | -0.0634386 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0600925 |
| TPM3 | tropomyosin 3 | -0.0596755 |
| CENPF | centromere protein F, 350/400kDa | -0.058153 |
| SQSTM1 | sequestosome 1 | -0.0567713 |
| TLN1 | talin 1 | -0.0536308 |
| ZNF841 | zinc finger protein 841 | -0.0531145 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0528264 |
| RND3 | Rho family GTPase 3 | -0.0526062 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0490638 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0485132 |
| TMSB4X | thymosin beta 4, X-linked | -0.0469223 |
| SRP54 | signal recognition particle 54kDa | -0.0458742 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0440251 |
| MSN | moesin | -0.0434208 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0428108 |
| H1-4 | H1.4 linker histone, cluster member | -0.0420832 |
| RPS2 | ribosomal protein S2 | -0.0413755 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0407331 |
| MKI67 | marker of proliferation Ki-67 | -0.0405965 |
| GOLT1B | golgi transport 1B | -0.0393099 |
| IL6ST | interleukin 6 signal transducer | -0.0392521 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0392139 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.038243 |
| PAPOLA | poly(A) polymerase alpha | -0.037111 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0367689 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0363805 |
| BRD2 | bromodomain containing 2 | -0.0355187 |
| PNN | pinin, desmosome associated protein | -0.0353059 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0353019 |
| CLTC | clathrin, heavy chain (Hc) | -0.0349193 |
| NKTR | natural killer cell triggering receptor | -0.0348479 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0347115 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0337478 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.0337352 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.0336892 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.033571 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0332688 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0331134 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0328919 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0321656 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0320061 |
| IRS2 | insulin receptor substrate 2 | -0.0309166 |
| TMF1 | TATA element modulatory factor 1 | -0.0307505 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0306381 |
| RIOK3 | RIO kinase 3 | -0.0304851 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.030429 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0304209 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0303711 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0302907 |
| TMEM39A | transmembrane protein 39A | -0.030216 |
| FSTL1 | follistatin-like 1 | -0.0298102 |
| KIF5B | kinesin family member 5B | -0.0296964 |
| MCL1 | myeloid cell leukemia 1 | -0.0295285 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0294495 |
| UBC | ubiquitin C | -0.0293366 |
| CEP350 | centrosomal protein 350kDa | -0.029191 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0288887 |
| GDI2 | GDP dissociation inhibitor 2 | -0.0287736 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0283521 |
| TPR | translocated promoter region, nuclear basket protein | -0.0280964 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0280289 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0276778 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.027597 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0275514 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.027546 |
| TSC22D2 | TSC22 domain family, member 2 | -0.027472 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0273834 |
| GOLGA4 | golgin A4 | -0.0273655 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.027365 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0273068 |
| AHNAK | AHNAK nucleoprotein | -0.0272005 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0268845 |
| UBXN4 | UBX domain protein 4 | -0.0265275 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0263108 |
| MEF2A | myocyte enhancer factor 2A | -0.0262106 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0260427 |
| HM13 | histocompatibility (minor) 13 | -0.0259996 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.025773 |
| RTN4 | reticulon 4 | -0.0255763 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | -0.0255443 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | -0.0255101 |
| DSG2 | desmoglein 2 | -0.0254171 |
| GPATCH2L | G patch domain containing 2-like | -0.025337 |
| RLIM | ring finger protein, LIM domain interacting | -0.0253041 |
| SUCO | SUN domain containing ossification factor | -0.0252001 |
| GOLGA3 | golgin A3 | -0.0250724 |
| PLPP3 | phospholipid phosphatase 3 | -0.0250613 |
| VIRMA | vir like m6A methyltransferase associated | -0.0250391 |
