| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxycycline (monohydrate) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Doxycycline (monohydrate)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.113834 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0962669 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0939557 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0728793 |
| KRT8 | keratin 8, type II | 0.0592932 |
| S100A6 | S100 calcium binding protein A6 | 0.045753 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0450438 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0423321 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0409786 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.037613 |
| LOC112694756 | uncharaterized LOC112694756 | 0.036965 |
| NPSR1 | neuropeptide S receptor 1 | 0.0365198 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0361853 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0357942 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0353314 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0347078 |
| SIK3 | SIK family kinase 3 | 0.0341989 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0328982 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0326017 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0325623 |
| CDK6 | cyclin-dependent kinase 6 | 0.0323801 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0322378 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0317365 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0306618 |
| HDAC9 | histone deacetylase 9 | 0.0297085 |
| KRT17 | keratin 17, type I | 0.0292156 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0292086 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.028506 |
| MSI2 | musashi RNA-binding protein 2 | 0.0274175 |
| KRT18 | keratin 18, type I | 0.0269773 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0269046 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0267262 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.026592 |
| TMSB10 | thymosin beta 10 | 0.0261757 |
| ANKRD11 | ankyrin repeat domain 11 | 0.026161 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0257202 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0255831 |
| KLHL29 | kelch-like family member 29 | 0.0254158 |
| LAMB3 | laminin, beta 3 | 0.0253673 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0251348 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.024946 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.024259 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0230616 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0229409 |
| RBM39 | RNA binding motif protein 39 | 0.0225051 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0223948 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0223862 |
| TFRC | transferrin receptor | 0.0223748 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0223031 |
| FASN | fatty acid synthase | 0.0221869 |
| FRMD5 | FERM domain containing 5 | 0.0221457 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0209162 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.0207594 |
| PGM3 | phosphoglucomutase 3 | 0.0205872 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0204899 |
| RAB14 | RAB14, member RAS oncogene family | 0.0202969 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.020086 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0200859 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0199163 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0199155 |
| NUP58 | nucleoporin 58 | 0.0198675 |
| NBAS | neuroblastoma amplified sequence | 0.0198506 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0197618 |
| FBXO42 | F-box protein 42 | 0.019623 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0195907 |
| SLK | STE20-like kinase | 0.0194788 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0194509 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.019433 |
| MAPK6 | mitogen-activated protein kinase 6 | 0.0190994 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0189825 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0188269 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0186065 |
| MUC1 | mucin 1, cell surface associated | 0.0184851 |
| GPX2 | glutathione peroxidase 2 | 0.0183487 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0182999 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0182302 |
| SQSTM1 | sequestosome 1 | 0.0181732 |
| PMM2 | phosphomannomutase 2 | 0.0181459 |
| STX18 | syntaxin 18 | 0.0181402 |
| TRIM31 | tripartite motif containing 31 | 0.0180764 |
| HLA-A | major histocompatibility complex, class I, A | 0.0179882 |
| HMGA1 | high mobility group AT-hook 1 | 0.017711 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.01771 |
| CALR | calreticulin | 0.017654 |
| AHR | aryl hydrocarbon receptor | 0.0175153 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0174313 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0173729 |
| SDC4 | syndecan 4 | 0.0173166 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0172277 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 | 0.0172162 |
| SRPRA | SRP receptor subunit alpha | 0.0171613 |
| ZNF207 | zinc finger protein 207 | 0.0171112 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0169792 |
| PIR | pirin (iron-binding nuclear protein) | 0.0168666 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0166767 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0165628 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0165321 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0162519 |
| LCN2 | lipocalin 2 | 0.0162424 |
| ARF1 | ADP-ribosylation factor 1 | 0.0161309 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.210821 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.151362 |
| EMP1 | epithelial membrane protein 1 | -0.114081 |
| ITGA6 | integrin, alpha 6 | -0.0925698 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0874944 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0813834 |
| ANLN | anillin, actin binding protein | -0.0729968 |
| LMO7 | LIM domain 7 | -0.0728151 |
| DSPP | dentin sialophosphoprotein | -0.0699885 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0693059 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0686513 |
| AHNAK | AHNAK nucleoprotein | -0.0685706 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0671772 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0649595 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0645427 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0600181 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0576834 |
| SNX9 | sorting nexin 9 | -0.0575267 |
| RPS6 | ribosomal protein S6 | -0.0568543 |
| GOLGB1 | golgin B1 | -0.0524707 |
| H1-0 | H1.0 linker histone | -0.0524504 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0502675 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0502264 |
| ASPH | aspartate beta-hydroxylase | -0.0497218 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0490312 |
| RRBP1 | ribosome binding protein 1 | -0.0478814 |
| B2M | beta-2-microglobulin | -0.0477457 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0476006 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0470863 |
| MKI67 | marker of proliferation Ki-67 | -0.0465564 |
| CD2AP | CD2-associated protein | -0.0463116 |
| DSG2 | desmoglein 2 | -0.0454449 |
| TMC5 | transmembrane channel-like 5 | -0.0447128 |
| LIMA1 | LIM domain and actin binding 1 | -0.0442112 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.044011 |
| RPS2 | ribosomal protein S2 | -0.0437331 |
| DSTN | destrin (actin depolymerizing factor) | -0.0435652 |
| BCL2L1 | BCL2-like 1 | -0.0430312 |
| BPTF | bromodomain PHD finger transcription factor | -0.0429341 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0407042 |
| LIPH | lipase, member H | -0.0406032 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0405317 |
| NDRG1 | N-myc downstream regulated 1 | -0.0404355 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.039205 |
| ARCN1 | archain 1 | -0.0391679 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0378422 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0369598 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0368225 |
| SEPTIN9 | septin 9 | -0.0365621 |
| ATM | ATM serine/threonine kinase | -0.0360585 |
| RPL19 | ribosomal protein L19 | -0.0358497 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0356832 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0350566 |
| HYOU1 | hypoxia up-regulated 1 | -0.0347529 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0346895 |
| WWC1 | WW and C2 domain containing 1 | -0.034487 |
| YAP1 | Yes-associated protein 1 | -0.0339853 |
| PRSS3 | protease, serine, 3 | -0.0333829 |
| TMEM45B | transmembrane protein 45B | -0.0333142 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0330666 |
| EHBP1 | EH domain binding protein 1 | -0.0327556 |
| FLNB | filamin B, beta | -0.0325398 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0324652 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0323594 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0321313 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0321047 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0319671 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0318745 |
| CDK19 | cyclin-dependent kinase 19 | -0.0317789 |
| RPS8 | ribosomal protein S8 | -0.0317614 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0317034 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0316377 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0314806 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0313394 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0311274 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0310937 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0309606 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0306004 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0303699 |
| RAD51B | RAD51 paralog B | -0.030346 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0303402 |
| FBXO11 | F-box protein 11 | -0.0298793 |
| ZNF292 | zinc finger protein 292 | -0.0297906 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0296487 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0296155 |
| EZR | ezrin | -0.029316 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0292224 |
| YEATS2 | YEATS domain containing 2 | -0.0289265 |
| MYO9A | myosin IXA | -0.028844 |
| S100A10 | S100 calcium binding protein A10 | -0.0280465 |
| NF1 | neurofibromin 1 | -0.0278079 |
| RPS25 | ribosomal protein S25 | -0.0276496 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0275914 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0272335 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0272177 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0270011 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0269101 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0266868 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0265769 |
| SETD5 | SET domain containing 5 | -0.0265086 |
