| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxycycline (monohydrate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Doxycycline (monohydrate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.246314 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.148863 |
| FAT1 | FAT atypical cadherin 1 | 0.115992 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.115445 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0927304 |
| FLNB | filamin B, beta | 0.0926754 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0835213 |
| CALB1 | calbindin 1, 28kDa | 0.0789488 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0695354 |
| TXNRD1 | thioredoxin reductase 1 | 0.0683486 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0639989 |
| EREG | epiregulin | 0.060142 |
| RPLP0 | ribosomal protein, large, P0 | 0.0589757 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0583405 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.058005 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0568974 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0558137 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0556028 |
| MED13L | mediator complex subunit 13-like | 0.0551714 |
| MYO1E | myosin IE | 0.0536924 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0533059 |
| SHROOM3 | shroom family member 3 | 0.0530536 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0498301 |
| VCL | vinculin | 0.0492528 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0484604 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0484405 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0472185 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0463153 |
| ANXA2 | annexin A2 | 0.0454691 |
| CANX | calnexin | 0.0452578 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0450947 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0445811 |
| ITGA6 | integrin, alpha 6 | 0.0441217 |
| LDHA | lactate dehydrogenase A | 0.0439255 |
| PRELID2 | PRELI domain containing 2 | 0.0428832 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0427891 |
| TRIM2 | tripartite motif containing 2 | 0.0427682 |
| PLAC8 | placenta-specific 8 | 0.0427137 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.042077 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0419314 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0407031 |
| KRT8 | keratin 8, type II | 0.0405894 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0390476 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0384416 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0381403 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0372829 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0368682 |
| GOLGA4 | golgin A4 | 0.0368512 |
| DSG3 | desmoglein 3 | 0.0366897 |
| TJP1 | tight junction protein 1 | 0.0362981 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0361219 |
| KIF5B | kinesin family member 5B | 0.0360415 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0359506 |
| PKP2 | plakophilin 2 | 0.0355635 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0353245 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0350614 |
| PRSS3 | protease, serine, 3 | 0.0347094 |
| USP3 | ubiquitin specific peptidase 3 | 0.0346519 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0345765 |
| TCF12 | transcription factor 12 | 0.0344978 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0340433 |
| ACTN4 | actinin, alpha 4 | 0.0340116 |
| MYOF | myoferlin | 0.0339947 |
| PCDHB16 | protocadherin beta 16 | 0.0338914 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0336663 |
| GDF15 | growth differentiation factor 15 | 0.0335708 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0330539 |
| YBX3 | Y box binding protein 3 | 0.0327196 |
| PKM | pyruvate kinase, muscle | 0.0325929 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0325603 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0324782 |
| FOXP1 | forkhead box P1 | 0.0324142 |
| MUC13 | mucin 13, cell surface associated | 0.0319934 |
| ETNK1 | ethanolamine kinase 1 | 0.0317004 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0316602 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0315851 |
| MATR3 | matrin 3 | 0.0315749 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0314898 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0313526 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0311641 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0305481 |
| CCPG1 | cell cycle progression 1 | 0.0303503 |
| RPS2 | ribosomal protein S2 | 0.0302121 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0302088 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0301156 |
| EPCAM | epithelial cell adhesion molecule | 0.0300843 |
| RNF145 | ring finger protein 145 | 0.0300799 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0296056 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0295136 |
| WWC1 | WW and C2 domain containing 1 | 0.0293846 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0292865 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0291778 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0288897 |
| CDC42SE2 | CDC42 small effector 2 | 0.0288511 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0288405 |
| SLMAP | sarcolemma associated protein | 0.0287602 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.028341 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0282468 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0282395 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0282257 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.0597682 |
| RPL31 | ribosomal protein L31 | -0.0539187 |
| RPS29 | ribosomal protein S29 | -0.0370647 |
| RPS23 | ribosomal protein S23 | -0.0360017 |
| RPLP2 | ribosomal protein, large, P2 | -0.034408 |
| RPL37A | ribosomal protein L37a | -0.0342442 |
| RPL35A | ribosomal protein L35a | -0.0308987 |
| HLA-B | major histocompatibility complex, class I, B | -0.0289154 |
| RPS11 | ribosomal protein S11 | -0.0284138 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0254741 |
| RPL38 | ribosomal protein L38 | -0.0247802 |
| FTL | ferritin, light polypeptide | -0.0227952 |
| INTS6 | integrator complex subunit 6 | -0.0222653 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0215054 |
| RPS10 | ribosomal protein S10 | -0.0209662 |
| RPL9 | ribosomal protein L9 | -0.0205369 |
| RPL36 | ribosomal protein L36 | -0.0197942 |
| NABP1 | nucleic acid binding protein 1 | -0.0196113 |
| LRRC23 | leucine rich repeat containing 23 | -0.0193447 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0185748 |
| RCC1 | regulator of chromosome condensation 1 | -0.0185032 |
| TMSB10 | thymosin beta 10 | -0.0181294 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0179344 |
| NPSR1 | neuropeptide S receptor 1 | -0.0177546 |
| FUS | FUS RNA binding protein | -0.0173049 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.016859 |
| RPS15 | ribosomal protein S15 | -0.0166133 |
| COG6 | component of oligomeric golgi complex 6 | -0.0164643 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0164063 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0161744 |
| NDRG1 | N-myc downstream regulated 1 | -0.0157493 |
| AGR2 | anterior gradient 2 | -0.0156613 |
| RPLP1 | ribosomal protein, large, P1 | -0.0155995 |
| RPS8 | ribosomal protein S8 | -0.0155567 |
| GOLGB1 | golgin B1 | -0.0154724 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0151797 |
| RPS6 | ribosomal protein S6 | -0.0151052 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0149274 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | -0.0146621 |
| FOXO3 | forkhead box O3 | -0.0145298 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0144217 |
| RPS13 | ribosomal protein S13 | -0.0142372 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.014046 |
| RPS14 | ribosomal protein S14 | -0.0137945 |
| RPS19 | ribosomal protein S19 | -0.0129887 |
| POU2F2 | POU class 2 homeobox 2 | -0.012873 |
| NOP56 | NOP56 ribonucleoprotein | -0.0125781 |
| RPL8 | ribosomal protein L8 | -0.0124213 |
| RPL28 | ribosomal protein L28 | -0.0122913 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0120613 |
| MCU | mitochondrial calcium uniporter | -0.0120002 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0118453 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0116992 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0115555 |
| UBAP2 | ubiquitin associated protein 2 | -0.0115522 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0114817 |
| SECISBP2 | SECIS binding protein 2 | -0.011303 |
| RPS25 | ribosomal protein S25 | -0.0112471 |
| SCFD2 | sec1 family domain containing 2 | -0.0110246 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0108874 |
| EGFR | epidermal growth factor receptor | -0.0108418 |
| MSH4 | mutS homolog 4 | -0.010829 |
| RPL27 | ribosomal protein L27 | -0.0108288 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | -0.0108171 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0107931 |
| USP36 | ubiquitin specific peptidase 36 | -0.0107617 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0107478 |
| MT2A | metallothionein 2A | -0.0107388 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | -0.0106363 |
| CCDC138 | coiled-coil domain containing 138 | -0.0103192 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0102712 |
| VIM | vimentin | -0.0102568 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0102143 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0101583 |
| TSLIG3A | tRNA splicing ligase complex subunit 3A | -0.0100809 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0100774 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0100056 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.00982198 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.00980802 |
| RPS24 | ribosomal protein S24 | -0.00979367 |
| PILRA | paired immunoglobin-like type 2 receptor alpha | -0.00979092 |
| NXF1 | nuclear RNA export factor 1 | -0.00965572 |
| RPL37 | ribosomal protein L37 | -0.00960046 |
| IL32 | interleukin 32 | -0.00958601 |
| TRIM72 | tripartite motif containing 72, E3 ubiquitin protein ligase | -0.00953375 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.00948159 |
| SUGT1 | SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) | -0.00947263 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0094568 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.0094289 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00937531 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.00931314 |
| RPL36A | ribosomal protein L36a | -0.00930942 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.00912185 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00905356 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.00897894 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.00888894 |
| FLNA | filamin A, alpha | -0.00888076 |
| FGF18 | fibroblast growth factor 18 | -0.00878154 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.00870896 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.00870187 |
