| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxycycline (monohydrate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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62 genes differentially expressed following the Doxycycline (monohydrate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.238397 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.216691 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.197642 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.195759 |
| PGK1 | phosphoglycerate kinase 1 | 0.163065 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.152741 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.115737 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.112026 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.106548 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.101554 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0987835 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.090375 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0829897 |
| ETNK1 | ethanolamine kinase 1 | 0.0794264 |
| ASPH | aspartate beta-hydroxylase | 0.0728117 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0679762 |
| DST | dystonin | 0.0635588 |
| RIGI | RNA sensor RIG-I | 0.0535662 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.053315 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0463771 |
| COL5A2 | collagen, type V, alpha 2 | 0.0462185 |
| JMJD1C | jumonji domain containing 1C | 0.0407817 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0388316 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0366331 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0293442 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0288662 |
| GPC6 | glypican 6 | 0.0196579 |
| FN1 | fibronectin 1 | 0.0178717 |
| EGFR | epidermal growth factor receptor | 0.0110353 |
| AREG | amphiregulin | 0.0107788 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00500707 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.295961 |
| FTL | ferritin, light polypeptide | -0.155834 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.140055 |
| EFNA5 | ephrin-A5 | -0.125905 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.123105 |
| TMSB10 | thymosin beta 10 | -0.117343 |
| PDE10A | phosphodiesterase 10A | -0.0958922 |
| CANX | calnexin | -0.0936826 |
| VIM | vimentin | -0.0896837 |
| RPS6 | ribosomal protein S6 | -0.0875008 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0860859 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0698176 |
| RPS8 | ribosomal protein S8 | -0.0676449 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0617253 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0615118 |
| RPL35A | ribosomal protein L35a | -0.0597772 |
| ENO1 | enolase 1, (alpha) | -0.0588731 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0501307 |
| GOLGA4 | golgin A4 | -0.0455206 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.045145 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0409649 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0254932 |
| MED13L | mediator complex subunit 13-like | -0.0227974 |
| TXNRD1 | thioredoxin reductase 1 | -0.0205299 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.020285 |
| OGA | O-GlcNAcase | -0.0190287 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0160121 |
| RBM39 | RNA binding motif protein 39 | -0.00950628 |
| PTMA | prothymosin, alpha | -0.0090091 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.00788567 |
| PRRC2C | proline-rich coiled-coil 2C | -0.00269639 |
