| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxycycline (monohydrate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxycycline (monohydrate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.135809 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.133204 |
| FNDC3B | fibronectin type III domain containing 3B | 0.101857 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0986164 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.095113 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0942911 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0913968 |
| SPAG9 | sperm associated antigen 9 | 0.0768134 |
| FBL | fibrillarin | 0.075364 |
| ZFP36 | ZFP36 ring finger protein | 0.0752297 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0750065 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0717993 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0706021 |
| FMNL2 | formin-like 2 | 0.0695082 |
| SEPTIN9 | septin 9 | 0.0640908 |
| ZNF292 | zinc finger protein 292 | 0.0636265 |
| SMAD3 | SMAD family member 3 | 0.0587891 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0582811 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0545119 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.052697 |
| XPO1 | exportin 1 | 0.0523577 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0508782 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0495512 |
| NAV2 | neuron navigator 2 | 0.0495358 |
| ENO1 | enolase 1, (alpha) | 0.0494844 |
| SBF2 | SET binding factor 2 | 0.0494621 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0488509 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.047527 |
| USP3 | ubiquitin specific peptidase 3 | 0.0473032 |
| ATP13A3 | ATPase type 13A3 | 0.0472949 |
| MED13L | mediator complex subunit 13-like | 0.0472909 |
| PDE10A | phosphodiesterase 10A | 0.0471946 |
| PTK2 | protein tyrosine kinase 2 | 0.0471924 |
| MATR3 | matrin 3 | 0.0467078 |
| PKM | pyruvate kinase, muscle | 0.0465643 |
| AFAP1 | actin filament associated protein 1 | 0.0454559 |
| PCBP2 | poly(rC) binding protein 2 | 0.0452122 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0450103 |
| CTBP2 | C-terminal binding protein 2 | 0.044692 |
| GOLGA4 | golgin A4 | 0.044004 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0423892 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0419287 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0415181 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0406389 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.040393 |
| YAP1 | Yes-associated protein 1 | 0.040063 |
| TFG | TRK-fused gene | 0.0397922 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.039569 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0392477 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0386575 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0382935 |
| HPCAL1 | hippocalcin-like 1 | 0.0380183 |
| HMGA1 | high mobility group AT-hook 1 | 0.0380125 |
| TXNRD1 | thioredoxin reductase 1 | 0.0379659 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0375544 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0370508 |
| NUP58 | nucleoporin 58 | 0.0369954 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0364532 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0363933 |
| TMEM123 | transmembrane protein 123 | 0.0362856 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0362562 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0359297 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0357271 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0355294 |
| CCNL1 | cyclin L1 | 0.0352095 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0351658 |
| SUCO | SUN domain containing ossification factor | 0.0350234 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0348323 |
| CDK19 | cyclin-dependent kinase 19 | 0.0346669 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0342875 |
| LDHA | lactate dehydrogenase A | 0.0341099 |
| WDR43 | WD repeat domain 43 | 0.0335218 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0334766 |
| MSN | moesin | 0.0333477 |
| POTEF | POTE ankyrin domain family, member F | 0.033309 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0331815 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0331084 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0327996 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0326828 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0323591 |
| RNF145 | ring finger protein 145 | 0.0323418 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0322985 |
| SNX14 | sorting nexin 14 | 0.0322856 |
| QKI | QKI, KH domain containing, RNA binding | 0.0316715 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0316282 |
| PHIP | pleckstrin homology domain interacting protein | 0.0315903 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.031125 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0310085 |
| DST | dystonin | 0.0309785 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0309137 |
| OLA1 | Obg-like ATPase 1 | 0.0308691 |
| ARRDC3 | arrestin domain containing 3 | 0.0304781 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0304256 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0303894 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.029992 |
| SEPTIN7 | septin 7 | 0.0299112 |
| NUP153 | nucleoporin 153kDa | 0.0296927 |
| TPD52 | tumor protein D52 | 0.0296915 |
| CENPF | centromere protein F, 350/400kDa | 0.0295945 |
| PGK1 | phosphoglycerate kinase 1 | 0.0294384 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.269302 |
| RPS16 | ribosomal protein S16 | -0.115131 |
| ZNF780B | zinc finger protein 780B | -0.0559719 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0553706 |
| EGR1 | early growth response 1 | -0.0494258 |
| RPL35A | ribosomal protein L35a | -0.0476553 |
| CD44 | CD44 molecule (Indian blood group) | -0.0452825 |
| VIM | vimentin | -0.0426019 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0412663 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0411814 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | -0.0397118 |
| AHNAK | AHNAK nucleoprotein | -0.039504 |
| RPLP2 | ribosomal protein, large, P2 | -0.0392168 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0381333 |
| FHL2 | four and a half LIM domains 2 | -0.0363818 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0355855 |
| OSMR | oncostatin M receptor | -0.0328479 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0327096 |
| RPS3 | ribosomal protein S3 | -0.0319636 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0309324 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0308698 |
| KLF6 | Kruppel-like factor 6 | -0.0299435 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0297293 |
| MYO1E | myosin IE | -0.0295063 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0293254 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0284663 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0280683 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0278833 |
| RPS24 | ribosomal protein S24 | -0.0273308 |
| RPS12 | ribosomal protein S12 | -0.0266306 |
| RPL12 | ribosomal protein L12 | -0.0264659 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0262163 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0261402 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0255912 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.025367 |
| RPL26 | ribosomal protein L26 | -0.0247728 |
| RASAL2 | RAS protein activator like 2 | -0.0244035 |
| EGFR | epidermal growth factor receptor | -0.0237385 |
| PHF14 | PHD finger protein 14 | -0.0232563 |
| HMGA2 | high mobility group AT-hook 2 | -0.023189 |
| TPM1 | tropomyosin 1 (alpha) | -0.0221075 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0220293 |
| MCL1 | myeloid cell leukemia 1 | -0.0220042 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0214654 |
| VMP1 | vacuole membrane protein 1 | -0.0212055 |
| SMYD3 | SET and MYND domain containing 3 | -0.0209994 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0208179 |
| RPS8 | ribosomal protein S8 | -0.0207337 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0207209 |
| NABP1 | nucleic acid binding protein 1 | -0.0202745 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0200775 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0199682 |
| MT2A | metallothionein 2A | -0.0199262 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0197337 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0196912 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0195212 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0195043 |
| IER3 | immediate early response 3 | -0.0194603 |
| RPL37A | ribosomal protein L37a | -0.0194281 |
| MED29 | mediator complex subunit 29 | -0.019343 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0191169 |
| RSU1 | Ras suppressor protein 1 | -0.0190083 |
| INTS6 | integrator complex subunit 6 | -0.0189037 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0188321 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0183469 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0183361 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0183007 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0180194 |
| YBX3 | Y box binding protein 3 | -0.0178965 |
| MYO9A | myosin IXA | -0.0178366 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0177054 |
| EHBP1 | EH domain binding protein 1 | -0.0176157 |
| RPLP1 | ribosomal protein, large, P1 | -0.0175529 |
| FAM120B | family with sequence similarity 120B | -0.0175192 |
| SYTL2 | synaptotagmin-like 2 | -0.0174441 |
| HDAC9 | histone deacetylase 9 | -0.0172134 |
| CAVIN1 | caveolae associated protein 1 | -0.0170875 |
| TBCA | tubulin folding cofactor A | -0.0169619 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0169052 |
| CDK13 | cyclin-dependent kinase 13 | -0.0167668 |
| RPS27A | ribosomal protein S27a | -0.016719 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0166285 |
| SYT1 | synaptotagmin I | -0.0163202 |
| LIMA1 | LIM domain and actin binding 1 | -0.0161997 |
| RPL36 | ribosomal protein L36 | -0.0161683 |
| TMSB10 | thymosin beta 10 | -0.0160496 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0159782 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0159271 |
| ZNF546 | zinc finger protein 546 | -0.0158902 |
| RPL34 | ribosomal protein L34 | -0.0158466 |
| RPS25 | ribosomal protein S25 | -0.0158389 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0156512 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0153969 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0153747 |
| NFX1 | nuclear transcription factor, X-box binding 1 | -0.0147858 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | -0.014763 |
| ATM | ATM serine/threonine kinase | -0.0147266 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0146522 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0145553 |
| TRIM66 | tripartite motif containing 66 | -0.0144818 |
