| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxycycline (monohydrate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxycycline (monohydrate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | 0.112032 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0803119 |
| MUC4 | mucin 4, cell surface associated | 0.0724605 |
| ACTG1 | actin gamma 1 | 0.0717901 |
| SMAD3 | SMAD family member 3 | 0.0715875 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0678531 |
| RPL37A | ribosomal protein L37a | 0.0666179 |
| INTS6 | integrator complex subunit 6 | 0.0661842 |
| RPL31 | ribosomal protein L31 | 0.0631122 |
| LMO7 | LIM domain 7 | 0.0624665 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0529887 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0506154 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0489438 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0484663 |
| MYO6 | myosin VI | 0.0451401 |
| RPL35A | ribosomal protein L35a | 0.0439907 |
| PDLIM5 | PDZ and LIM domain 5 | 0.043819 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.043683 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0435875 |
| LAMB3 | laminin, beta 3 | 0.0431025 |
| TJP1 | tight junction protein 1 | 0.0424541 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0402876 |
| RPS29 | ribosomal protein S29 | 0.0402354 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.039984 |
| RPS27A | ribosomal protein S27a | 0.03904 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0374749 |
| RCOR1 | REST corepressor 1 | 0.0374092 |
| RPL37 | ribosomal protein L37 | 0.0371409 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0364116 |
| RPS23 | ribosomal protein S23 | 0.0362004 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0361184 |
| AFDN | afadin, adherens junction formation factor | 0.0354936 |
| KRT8 | keratin 8, type II | 0.0354002 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.035333 |
| RPS10 | ribosomal protein S10 | 0.0351911 |
| KRT17 | keratin 17, type I | 0.0348988 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0344159 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0341914 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0339545 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0337744 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0329473 |
| LAMC2 | laminin, gamma 2 | 0.0326014 |
| MYO5B | myosin VB | 0.0325815 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0325381 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0324156 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0323527 |
| SPAG9 | sperm associated antigen 9 | 0.0322577 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0321774 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0315871 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0313363 |
| BRD2 | bromodomain containing 2 | 0.0312484 |
| RPS17 | ribosomal protein S17 | 0.0307948 |
| FMNL2 | formin-like 2 | 0.0307265 |
| HDAC9 | histone deacetylase 9 | 0.0306639 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0306233 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0305127 |
| RPL13A | ribosomal protein L13a | 0.0304174 |
| ACTN4 | actinin, alpha 4 | 0.0303405 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0301319 |
| RPS12 | ribosomal protein S12 | 0.0300342 |
| ERBIN | erbb2 interacting protein | 0.0294559 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.029255 |
| RPS8 | ribosomal protein S8 | 0.0290626 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0290205 |
| PARD3 | par-3 family cell polarity regulator | 0.0287799 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0285174 |
| RYK | receptor-like tyrosine kinase | 0.0285102 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0282582 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | 0.0278432 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0276412 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0276147 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.027184 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0270569 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0269908 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0266892 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0263915 |
| GPHN | gephyrin | 0.02623 |
| RPS6 | ribosomal protein S6 | 0.0261745 |
| USP12 | ubiquitin specific peptidase 12 | 0.026155 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0261375 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0261311 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0260024 |
| RPS13 | ribosomal protein S13 | 0.0258202 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0249517 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0248291 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0248243 |
| TRAF3 | TNF receptor-associated factor 3 | 0.0247568 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0247241 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0247217 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0247101 |
| KYNU | kynureninase | 0.024619 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.024574 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0245603 |
| FRMD6 | FERM domain containing 6 | 0.0245541 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0243711 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0243698 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0242627 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0239079 |
| ATP13A3 | ATPase type 13A3 | 0.0239049 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0236184 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.349034 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.153127 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.141557 |
| KRT19 | keratin 19, type I | -0.118127 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0964293 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.090999 |
| TXNIP | thioredoxin interacting protein | -0.0876822 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0658007 |
| MT2A | metallothionein 2A | -0.0630603 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0624717 |
| EZR | ezrin | -0.0624121 |
| NDRG1 | N-myc downstream regulated 1 | -0.0612115 |
| MKI67 | marker of proliferation Ki-67 | -0.0574047 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0566218 |
| FOSL1 | FOS-like antigen 1 | -0.056369 |
| TMSB4X | thymosin beta 4, X-linked | -0.056237 |
| EMP1 | epithelial membrane protein 1 | -0.055415 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0539447 |
| LDHA | lactate dehydrogenase A | -0.0538987 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0538018 |
| TMSB10 | thymosin beta 10 | -0.0535665 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0532878 |
| CDCP1 | CUB domain containing protein 1 | -0.0523707 |
| DSG2 | desmoglein 2 | -0.0518772 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0514777 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0488034 |
| TPI1 | triosephosphate isomerase 1 | -0.0487589 |
| CENPF | centromere protein F, 350/400kDa | -0.0485996 |
| PGK1 | phosphoglycerate kinase 1 | -0.0481193 |
| S100A6 | S100 calcium binding protein A6 | -0.0473933 |
| TMEM123 | transmembrane protein 123 | -0.0465249 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0444386 |
| EGR1 | early growth response 1 | -0.0439907 |
| AHNAK | AHNAK nucleoprotein | -0.0434409 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0429531 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0425725 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0417862 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0415589 |
| ANLN | anillin, actin binding protein | -0.0402703 |
| YBX3 | Y box binding protein 3 | -0.0401719 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.039798 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.038598 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0377139 |
| B2M | beta-2-microglobulin | -0.0372677 |
| LAMA4 | laminin, alpha 4 | -0.0371767 |
| H1-0 | H1.0 linker histone | -0.0371434 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0362164 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0360728 |
| MT1X | metallothionein 1X | -0.035686 |
| CBX3 | chromobox homolog 3 | -0.0353846 |
| CANX | calnexin | -0.0341754 |
| HMGA1 | high mobility group AT-hook 1 | -0.0336311 |
| VIM | vimentin | -0.0334935 |
| IRS2 | insulin receptor substrate 2 | -0.0322731 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0313687 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0303964 |
| ANXA2 | annexin A2 | -0.0299314 |
| RPLP1 | ribosomal protein, large, P1 | -0.0295838 |
| ANXA1 | annexin A1 | -0.0294567 |
| CLMN | calmin (calponin-like, transmembrane) | -0.0291607 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0284942 |
| ENO1 | enolase 1, (alpha) | -0.0280027 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0279224 |
| HMGB2 | high mobility group box 2 | -0.0278239 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0273142 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0268257 |
| S100A9 | S100 calcium binding protein A9 | -0.0267378 |
| EPCAM | epithelial cell adhesion molecule | -0.0266673 |
| RPL18 | ribosomal protein L18 | -0.0259237 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0257901 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0253729 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0253062 |
| KRT18 | keratin 18, type I | -0.0252204 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0251058 |
| S100A10 | S100 calcium binding protein A10 | -0.0245705 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0242159 |
| RRBP1 | ribosome binding protein 1 | -0.0237842 |
| EHF | ets homologous factor | -0.0237804 |
| ITGA6 | integrin, alpha 6 | -0.0237529 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0234831 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0234649 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0233963 |
| PKM | pyruvate kinase, muscle | -0.023386 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.023376 |
| STK17B | serine/threonine kinase 17b | -0.0232091 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0230066 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0222248 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.021985 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0219083 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0216969 |
| CCNI | cyclin I | -0.0216701 |
| H3-3B | H3.3 histone B | -0.0216053 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0214573 |
| NRP1 | neuropilin 1 | -0.0212157 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.020686 |
| CALU | calumenin | -0.0202122 |
| PLAT | plasminogen activator, tissue | -0.0200722 |
| DIAPH3 | diaphanous-related formin 3 | -0.020046 |
| NFIB | nuclear factor I/B | -0.0199815 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0199531 |
