| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxycycline (monohydrate) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Doxycycline (monohydrate)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF438 | zinc finger protein 438 | 0.0832103 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0828052 |
| NAV3 | neuron navigator 3 | 0.080414 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0702888 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0644599 |
| FLNB | filamin B, beta | 0.0600618 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0577286 |
| PTK2 | protein tyrosine kinase 2 | 0.0553901 |
| HDAC9 | histone deacetylase 9 | 0.0549665 |
| BNC2 | basonuclin 2 | 0.0524603 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.052321 |
| PARD3 | par-3 family cell polarity regulator | 0.0506805 |
| FRMD4A | FERM domain containing 4A | 0.0500529 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.049484 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0466553 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0460074 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0449897 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0439661 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0422537 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0417774 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0413418 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0395633 |
| FRMD6 | FERM domain containing 6 | 0.0391824 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0389856 |
| WDR43 | WD repeat domain 43 | 0.0385116 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0384102 |
| CALD1 | caldesmon 1 | 0.035784 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0357593 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 0.0353485 |
| RAD51B | RAD51 paralog B | 0.0348978 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0341793 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0340857 |
| SRPK2 | SRSF protein kinase 2 | 0.0334582 |
| HMGA2 | high mobility group AT-hook 2 | 0.0308954 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0303127 |
| ZNF292 | zinc finger protein 292 | 0.0295133 |
| FMNL2 | formin-like 2 | 0.0282914 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0281395 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0280279 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.02778 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0268991 |
| FHIT | fragile histidine triad | 0.026763 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0264812 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0263287 |
| LAMB3 | laminin, beta 3 | 0.0262103 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.025626 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0253977 |
| NAV2 | neuron navigator 2 | 0.0252677 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0247576 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0245008 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0237321 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0235775 |
| OLA1 | Obg-like ATPase 1 | 0.0231987 |
| USP3 | ubiquitin specific peptidase 3 | 0.0227527 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0227435 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.022657 |
| ATP13A3 | ATPase type 13A3 | 0.0226446 |
| EXOC4 | exocyst complex component 4 | 0.0222457 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0216496 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0214345 |
| TTR | transthyretin | 0.0211102 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.020649 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0204767 |
| MSI2 | musashi RNA-binding protein 2 | 0.0204725 |
| DENND1A | DENN/MADD domain containing 1A | 0.0202122 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0200144 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.019927 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.019632 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0195325 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0194807 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0194649 |
| RAB3IP | RAB3A interacting protein | 0.0193134 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.019289 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0189872 |
| MTMR3 | myotubularin related protein 3 | 0.0187468 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0186233 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0185467 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0184626 |
| MEF2A | myocyte enhancer factor 2A | 0.0184441 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0183028 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0181152 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0180805 |
| TRRAP | transformation/transcription domain-associated protein | 0.017974 |
| CAST | calpastatin | 0.0178081 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0175635 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0175426 |
| PDS5B | PDS5 cohesin associated factor B | 0.0175025 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0174896 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0174802 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0171078 |
| RASA2 | RAS p21 protein activator 2 | 0.0171067 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0171061 |
| ANK2 | ankyrin 2, neuronal | 0.0168461 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0168267 |
| DGKI | diacylglycerol kinase, iota | 0.0166515 |
| XPO1 | exportin 1 | 0.0166342 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0162087 |
| SBF2 | SET binding factor 2 | 0.0156035 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0155838 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0155305 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | -0.139051 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116193 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0671486 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0563048 |
| TXNRD1 | thioredoxin reductase 1 | -0.0420664 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0390173 |
| AHNAK | AHNAK nucleoprotein | -0.0384126 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0358979 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0348341 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0347828 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0306218 |
| UBC | ubiquitin C | -0.0303382 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0299014 |
| UPP1 | uridine phosphorylase 1 | -0.0289204 |
| RPS2 | ribosomal protein S2 | -0.0288387 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0287669 |
| RPL7A | ribosomal protein L7a | -0.0276145 |
| JMJD1C | jumonji domain containing 1C | -0.0274951 |
| CAPRIN2 | caprin family member 2 | -0.0269365 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0248918 |
| CD44 | CD44 molecule (Indian blood group) | -0.0246755 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0246432 |
| RPL11 | ribosomal protein L11 | -0.0244997 |
| STK4 | serine/threonine kinase 4 | -0.0238635 |
| RPL7 | ribosomal protein L7 | -0.0237537 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0236914 |
| RPL8 | ribosomal protein L8 | -0.0231721 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0231341 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0230024 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0228162 |
| RPS25 | ribosomal protein S25 | -0.0227691 |
| TUT7 | terminal uridylyl transferase 7 | -0.0226518 |
| SGMS2 | sphingomyelin synthase 2 | -0.0225694 |
| RPL38 | ribosomal protein L38 | -0.0225342 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.022037 |
| RPL12 | ribosomal protein L12 | -0.0219815 |
| USP34 | ubiquitin specific peptidase 34 | -0.0213813 |
| RPL19 | ribosomal protein L19 | -0.0209128 |
| CTTNBP2NL | CTTNBP2 N-terminal like | -0.0198676 |
| MKI67 | marker of proliferation Ki-67 | -0.0197801 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0197391 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0194434 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0191783 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0191495 |
| RPS18 | ribosomal protein S18 | -0.0189985 |
| G0S2 | G0/G1 switch 2 | -0.018917 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.018346 |
| ADAR | adenosine deaminase, RNA-specific | -0.0180644 |
| RPS13 | ribosomal protein S13 | -0.0180576 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0180505 |
| RPL26 | ribosomal protein L26 | -0.0180184 |
| RECQL | RecQ helicase-like | -0.0179543 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0179465 |
| MYO9B | myosin IXB | -0.017481 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.01706 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0170523 |
| BRD2 | bromodomain containing 2 | -0.0168527 |
| RPS8 | ribosomal protein S8 | -0.0168082 |
| S100A10 | S100 calcium binding protein A10 | -0.0166036 |
| RPLP2 | ribosomal protein, large, P2 | -0.0165959 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0165881 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.016553 |
| CALU | calumenin | -0.0165025 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0164816 |
| RTN4 | reticulon 4 | -0.0162882 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.016219 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.016129 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0159421 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.01578 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.015757 |
| RPS5 | ribosomal protein S5 | -0.0157042 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0156225 |
| RPL9 | ribosomal protein L9 | -0.0156073 |
| B2M | beta-2-microglobulin | -0.015382 |
| PKM | pyruvate kinase, muscle | -0.0153253 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | -0.0153167 |
| MYO9A | myosin IXA | -0.0152818 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0152492 |
| RNF24 | ring finger protein 24 | -0.0152124 |
| WASL | Wiskott-Aldrich syndrome-like | -0.0151666 |
| RPS6 | ribosomal protein S6 | -0.0151079 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0150737 |
| RPS15 | ribosomal protein S15 | -0.0149711 |
| WDR26 | WD repeat domain 26 | -0.0149377 |
| RPS23 | ribosomal protein S23 | -0.0148448 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0147867 |
| CLTC | clathrin, heavy chain (Hc) | -0.0146592 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0146441 |
| RPS27A | ribosomal protein S27a | -0.014644 |
| PRELID2 | PRELI domain containing 2 | -0.0143873 |
| FHL2 | four and a half LIM domains 2 | -0.0143841 |
| EMP1 | epithelial membrane protein 1 | -0.0142513 |
| MCL1 | myeloid cell leukemia 1 | -0.0142452 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0142272 |
| EXOC6B | exocyst complex component 6B | -0.0137649 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0137325 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0136657 |
| SYAP1 | synapse associated protein 1 | -0.0136644 |
| TPX2 | TPX2, microtubule-associated | -0.0136392 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0135848 |
