| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxycycline (monohydrate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxycycline (monohydrate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TENT5A | terminal nucleotidyltransferase 5A | 0.0675243 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0657268 |
| NDRG1 | N-myc downstream regulated 1 | 0.0611084 |
| TENM2 | teneurin transmembrane protein 2 | 0.0606602 |
| RUNX1 | runt-related transcription factor 1 | 0.059592 |
| CDH13 | cadherin 13 | 0.0529027 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0522232 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.052181 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0500401 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0486538 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0469485 |
| RPL7 | ribosomal protein L7 | 0.0457753 |
| PDE10A | phosphodiesterase 10A | 0.0455363 |
| FMNL2 | formin-like 2 | 0.0447283 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.044482 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0435526 |
| EFNA5 | ephrin-A5 | 0.0432371 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0429907 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0427997 |
| PRELID2 | PRELI domain containing 2 | 0.042194 |
| TENM1 | teneurin transmembrane protein 1 | 0.0417567 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.0412624 |
| NAV1 | neuron navigator 1 | 0.0409577 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.040796 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0403695 |
| POTEF | POTE ankyrin domain family, member F | 0.0398403 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0397056 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0395737 |
| NRXN3 | neurexin 3 | 0.0392009 |
| FHIT | fragile histidine triad | 0.0378172 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0378064 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0377788 |
| LAMB3 | laminin, beta 3 | 0.0374377 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0367621 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0362704 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0362187 |
| NRG1 | neuregulin 1 | 0.0357381 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0353204 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0352465 |
| BMERB1 | bMERB domain containing 1 | 0.0350145 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0347927 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0347745 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0346983 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0338972 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.033606 |
| SLMAP | sarcolemma associated protein | 0.0333884 |
| XPO1 | exportin 1 | 0.0328277 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0327955 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0327625 |
| SEC24A | SEC24 family member A | 0.0326938 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0326862 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0325417 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0323721 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0322783 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | 0.0318694 |
| WDR59 | WD repeat domain 59 | 0.0318659 |
| FNIP1 | folliculin interacting protein 1 | 0.0318012 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0317854 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0313436 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0312297 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0308493 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0307588 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0306396 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase | 0.0305283 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0304354 |
| MSI2 | musashi RNA-binding protein 2 | 0.0300747 |
| TENM3 | teneurin transmembrane protein 3 | 0.0299248 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0297251 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0295459 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.029186 |
| OGA | O-GlcNAcase | 0.028884 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0288619 |
| RIN2 | Ras and Rab interactor 2 | 0.0286934 |
| RPS2 | ribosomal protein S2 | 0.02868 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0286534 |
| MAPK6 | mitogen-activated protein kinase 6 | 0.0286378 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.028343 |
| CMIP | c-Maf inducing protein | 0.0283294 |
| RAP1A | RAP1A, member of RAS oncogene family | 0.028274 |
| RPL34 | ribosomal protein L34 | 0.0282613 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0282092 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0281539 |
| PYGL | phosphorylase, glycogen, liver | 0.028081 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0280734 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0280454 |
| MORF4L1 | mortality factor 4 like 1 | 0.0279327 |
| VEGFA | vascular endothelial growth factor A | 0.0277311 |
| ASTN2 | astrotactin 2 | 0.0276478 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0276044 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.027599 |
| GOLGA4 | golgin A4 | 0.0275314 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0272115 |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing | 0.0272104 |
| YBX1 | Y box binding protein 1 | 0.0269204 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0268322 |
| RORA | RAR-related orphan receptor A | 0.0267967 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0267341 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.026614 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.026494 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0264218 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.242482 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.191298 |
| COL6A3 | collagen, type VI, alpha 3 | -0.123542 |
| COL1A1 | collagen, type I, alpha 1 | -0.121211 |
| COL1A2 | collagen, type I, alpha 2 | -0.115931 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.101252 |
| AHNAK | AHNAK nucleoprotein | -0.0938273 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0909397 |
| UBC | ubiquitin C | -0.0901671 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0841653 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.082143 |
| GRB10 | growth factor receptor-bound protein 10 | -0.079607 |
| TMSB10 | thymosin beta 10 | -0.0774256 |
| LOX | lysyl oxidase | -0.0766361 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0764959 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0762077 |
| SPAG9 | sperm associated antigen 9 | -0.0758594 |
| SDC4 | syndecan 4 | -0.0742144 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0719253 |
| FN1 | fibronectin 1 | -0.0608796 |
| LOXL2 | lysyl oxidase-like 2 | -0.0599669 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0578953 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0572871 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0572618 |
| CALU | calumenin | -0.0567489 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0555587 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0543749 |
| ANXA5 | annexin A5 | -0.0537567 |
| SRPK2 | SRSF protein kinase 2 | -0.0536268 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0513214 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0509714 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0505581 |
| MEF2A | myocyte enhancer factor 2A | -0.050258 |
| ENO1 | enolase 1, (alpha) | -0.0497655 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0491698 |
| CDK6 | cyclin-dependent kinase 6 | -0.0472083 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0468221 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0457556 |
| HLA-B | major histocompatibility complex, class I, B | -0.0454708 |
| MT2A | metallothionein 2A | -0.0453253 |
| EGFR | epidermal growth factor receptor | -0.0441379 |
| THOC2 | THO complex 2 | -0.0435028 |
| COL6A2 | collagen, type VI, alpha 2 | -0.043039 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0423447 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.042236 |
| AFAP1 | actin filament associated protein 1 | -0.0419706 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0418427 |
| HIP1 | huntingtin interacting protein 1 | -0.0416787 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0411081 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0404271 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0400939 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0392749 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0392745 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0392744 |
| RTN4 | reticulon 4 | -0.0388375 |
| CD109 | CD109 molecule | -0.0384238 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0380197 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.037521 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0373614 |
| FAM20C | family with sequence similarity 20, member C | -0.0361104 |
| CALR | calreticulin | -0.0356946 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0355786 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0355627 |
| GANAB | glucosidase, alpha; neutral AB | -0.0346629 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0346588 |
| CUL4B | cullin 4B | -0.0343745 |
| RIGI | RNA sensor RIG-I | -0.0342489 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0341182 |
| CD44 | CD44 molecule (Indian blood group) | -0.034055 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0339531 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0338606 |
| CCNI | cyclin I | -0.0338277 |
| TXNIP | thioredoxin interacting protein | -0.0337525 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0336708 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0336616 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0332445 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0332047 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0330336 |
| PGK1 | phosphoglycerate kinase 1 | -0.0321927 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.031664 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0316321 |
| HDLBP | high density lipoprotein binding protein | -0.0316254 |
| H3-3B | H3.3 histone B | -0.0314845 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -0.0314786 |
| RRBP1 | ribosome binding protein 1 | -0.0305879 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0304902 |
| VIM | vimentin | -0.0303653 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0303219 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.030128 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0299481 |
| TPM4 | tropomyosin 4 | -0.0297758 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0295168 |
| SERINC3 | serine incorporator 3 | -0.0291837 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0291535 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0290083 |
| USP47 | ubiquitin specific peptidase 47 | -0.0285751 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0279775 |
| IL6 | interleukin 6 | -0.0279268 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.027867 |
| RLF | rearranged L-myc fusion | -0.0278582 |
