| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxycycline (monohydrate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxycycline (monohydrate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.115941 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0782279 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0666974 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0621147 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0491937 |
| PARD3 | par-3 family cell polarity regulator | 0.0418883 |
| ANXA2 | annexin A2 | 0.0418777 |
| TFG | TRK-fused gene | 0.0412504 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0406278 |
| TMSB10 | thymosin beta 10 | 0.0399578 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0393977 |
| CRY1 | cryptochrome circadian clock 1 | 0.0388704 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.038793 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0382623 |
| RNF145 | ring finger protein 145 | 0.0382475 |
| SPAG9 | sperm associated antigen 9 | 0.0375588 |
| CAPRIN2 | caprin family member 2 | 0.0374003 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0368851 |
| RHEB | Ras homolog enriched in brain | 0.0323161 |
| FMNL2 | formin-like 2 | 0.0313995 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.031379 |
| USP3 | ubiquitin specific peptidase 3 | 0.0304403 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0301904 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0300467 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0291832 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0282402 |
| CUL5 | cullin 5 | 0.0277317 |
| SDC4 | syndecan 4 | 0.0267671 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0266962 |
| COG5 | component of oligomeric golgi complex 5 | 0.0266089 |
| ZNF292 | zinc finger protein 292 | 0.0262684 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0261655 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0260964 |
| VIM | vimentin | 0.0258253 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0258169 |
| HBP1 | HMG-box transcription factor 1 | 0.0256996 |
| GPR107 | G protein-coupled receptor 107 | 0.0256123 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0254814 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0254243 |
| RNF111 | ring finger protein 111 | 0.0253986 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0246059 |
| MORF4L1 | mortality factor 4 like 1 | 0.0242566 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0241935 |
| UBE2Q2 | ubiquitin-conjugating enzyme E2Q family member 2 | 0.0240384 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0238663 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0238503 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0238204 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0237757 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0234595 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0232418 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0230649 |
| IER3 | immediate early response 3 | 0.0230636 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0230508 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0227327 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.022723 |
| XPO1 | exportin 1 | 0.0226212 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0222994 |
| SKIL | SKI-like proto-oncogene | 0.0222198 |
| ARRDC3 | arrestin domain containing 3 | 0.0220851 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.022056 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0220394 |
| PDCD10 | programmed cell death 10 | 0.0220223 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0219991 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0216983 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0215803 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0210533 |
| MAP1B | microtubule-associated protein 1B | 0.0210446 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0210144 |
| PDS5B | PDS5 cohesin associated factor B | 0.020808 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0207503 |
| RBM39 | RNA binding motif protein 39 | 0.0207412 |
| NUP58 | nucleoporin 58 | 0.0207333 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0206544 |
| TTK | TTK protein kinase | 0.0206429 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0205911 |
| ECT2 | epithelial cell transforming 2 | 0.0205007 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0202864 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0200342 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0200246 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0197626 |
| OLA1 | Obg-like ATPase 1 | 0.0197594 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0197146 |
| HMGA2 | high mobility group AT-hook 2 | 0.0197105 |
| WDR43 | WD repeat domain 43 | 0.0196917 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0194569 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.019411 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0193529 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0193068 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0191404 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 0.0190654 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | 0.0190327 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0188826 |
| NUP54 | nucleoporin 54kDa | 0.018882 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.018821 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0187926 |
| SEC24A | SEC24 family member A | 0.0187681 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0187213 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0186827 |
| CORO1C | coronin, actin binding protein, 1C | 0.0186788 |
| PKM | pyruvate kinase, muscle | 0.0186554 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.378144 |
| SMYD3 | SET and MYND domain containing 3 | -0.0777572 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0647486 |
| GOLGA4 | golgin A4 | -0.0635675 |
| YBX3 | Y box binding protein 3 | -0.063075 |
| ATM | ATM serine/threonine kinase | -0.0599783 |
| TPX2 | TPX2, microtubule-associated | -0.0534579 |
| CD44 | CD44 molecule (Indian blood group) | -0.0528098 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0518262 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0505771 |
| CPNE1 | copine I | -0.05039 |
| CENPF | centromere protein F, 350/400kDa | -0.0503296 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0490547 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0479847 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0456194 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0427176 |
| ANKRD12 | ankyrin repeat domain 12 | -0.04245 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0420091 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0419413 |
| PHF20 | PHD finger protein 20 | -0.0416897 |
| GOLGB1 | golgin B1 | -0.0413181 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0411876 |
| NF1 | neurofibromin 1 | -0.0411597 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0403342 |
| FNIP1 | folliculin interacting protein 1 | -0.0393634 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0393057 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.038135 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0376209 |
| RRBP1 | ribosome binding protein 1 | -0.0375296 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0353832 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0343189 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0341898 |
| TPR | translocated promoter region, nuclear basket protein | -0.0327292 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.031982 |
| CEP57 | centrosomal protein 57kDa | -0.031891 |
| ANO6 | anoctamin 6 | -0.0315616 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0309991 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0309396 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0307711 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0306253 |
| ERBIN | erbb2 interacting protein | -0.0301825 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0300743 |
| CENPE | centromere protein E, 312kDa | -0.0291722 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0284477 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0281964 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0279517 |
| OSMR | oncostatin M receptor | -0.0273814 |
| OSBPL6 | oxysterol binding protein-like 6 | -0.0273393 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0273242 |
| SNX14 | sorting nexin 14 | -0.0264732 |
| DEK | DEK proto-oncogene | -0.0264705 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0264389 |
| ANLN | anillin, actin binding protein | -0.0264355 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0263883 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0263264 |
| NBEAL1 | neurobeachin-like 1 | -0.0263046 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0261409 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0259658 |
| TMEM245 | transmembrane protein 245 | -0.0257674 |
| DST | dystonin | -0.0256966 |
| RPL36 | ribosomal protein L36 | -0.0253257 |
| CDCP1 | CUB domain containing protein 1 | -0.0251133 |
| AURKA | aurora kinase A | -0.0249343 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0247745 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0246498 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.024515 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0244282 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0243112 |
| CEP350 | centrosomal protein 350kDa | -0.0242359 |
| KIF4A | kinesin family member 4A | -0.0240913 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0237334 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0237104 |
| AK1 | adenylate kinase 1 | -0.0236988 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0236634 |
| RPL26 | ribosomal protein L26 | -0.0236602 |
| EFL1 | elongation factor like GTPase 1 | -0.023614 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0234813 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0233966 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0233482 |
| CENPP | centromere protein P | -0.0231237 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0230292 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0229509 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0228996 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0228993 |
| RPL38 | ribosomal protein L38 | -0.0227904 |
| SQSTM1 | sequestosome 1 | -0.0225955 |
| METTL15 | methyltransferase like 15 | -0.0225744 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0225204 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0224391 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0222648 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0222392 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0222352 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0222344 |
| KIF20B | kinesin family member 20B | -0.0221955 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -0.0219133 |
| INVS | inversin | -0.0218454 |
| KIF2A | kinesin heavy chain member 2A | -0.0217586 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0216979 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0215845 |
| TMEM167A | transmembrane protein 167A | -0.0215 |
