| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxycycline (monohydrate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxycycline (monohydrate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RCOR1 | REST corepressor 1 | 0.0569947 |
| MYO5B | myosin VB | 0.0447887 |
| ANKRD10 | ankyrin repeat domain 10 | 0.043689 |
| HMGA2 | high mobility group AT-hook 2 | 0.0407518 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0405234 |
| WDR43 | WD repeat domain 43 | 0.0352474 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0350442 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0345235 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0336078 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0321175 |
| FERMT1 | fermitin family member 1 | 0.0318325 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.031009 |
| RAB10 | RAB10, member RAS oncogene family | 0.0301175 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0291265 |
| TXNRD1 | thioredoxin reductase 1 | 0.0289973 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0288809 |
| DIAPH1 | diaphanous-related formin 1 | 0.0288043 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | 0.028791 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0284374 |
| SEPTIN9 | septin 9 | 0.0279332 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0274075 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0271555 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0269861 |
| FLOT1 | flotillin 1 | 0.0269086 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0262591 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0260866 |
| LAMA4 | laminin, alpha 4 | 0.0259536 |
| RREB1 | ras responsive element binding protein 1 | 0.0259093 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0258181 |
| TFRC | transferrin receptor | 0.0252904 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0248167 |
| SMAD3 | SMAD family member 3 | 0.0242865 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0235896 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0231649 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0219512 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.021941 |
| SMYD3 | SET and MYND domain containing 3 | 0.0218635 |
| WAC | WW domain containing adaptor with coiled-coil | 0.021708 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0216888 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0211236 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0206614 |
| SPAG9 | sperm associated antigen 9 | 0.0206097 |
| NCKAP1 | NCK-associated protein 1 | 0.0198402 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0196276 |
| LAMB3 | laminin, beta 3 | 0.0195888 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0193077 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0192993 |
| IPO7 | importin 7 | 0.0189834 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0187608 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0187552 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0186787 |
| DSPP | dentin sialophosphoprotein | 0.0185098 |
| MTAP | methylthioadenosine phosphorylase | 0.0183146 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0182941 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0180182 |
| GPC5 | glypican 5 | 0.0178847 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.0174273 |
| TNS3 | tensin 3 | 0.0172896 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0171605 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0169186 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0169165 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0168829 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0168822 |
| FMNL2 | formin-like 2 | 0.0163723 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0161454 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0161446 |
| SIK3 | SIK family kinase 3 | 0.0160864 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0160845 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.015998 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0158794 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0157927 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0157416 |
| RHEB | Ras homolog enriched in brain | 0.0157365 |
| AGO2 | argonaute RISC catalytic component 2 | 0.015732 |
| FHIT | fragile histidine triad | 0.0157182 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0156379 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0155909 |
| KLC1 | kinesin light chain 1 | 0.0155503 |
| RTN4 | reticulon 4 | 0.015544 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.0154171 |
| DENND1A | DENN/MADD domain containing 1A | 0.015279 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0151504 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0151281 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0151061 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0149008 |
| XYLT1 | xylosyltransferase I | 0.0144318 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0144147 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0143342 |
| DSC3 | desmocollin 3 | 0.0143207 |
| CCNY | cyclin Y | 0.0142628 |
| RAB21 | RAB21, member RAS oncogene family | 0.0142048 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0140543 |
| RLF | rearranged L-myc fusion | 0.0139284 |
| RNF43 | ring finger protein 43 | 0.0139064 |
| SLK | STE20-like kinase | 0.0138364 |
| EXT1 | exostosin glycosyltransferase 1 | 0.013688 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.013679 |
| TRAF3 | TNF receptor-associated factor 3 | 0.013411 |
| BMP2K | BMP2 inducible kinase | 0.0133422 |
| MEF2A | myocyte enhancer factor 2A | 0.0131905 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.188461 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.127338 |
| ANXA1 | annexin A1 | -0.104894 |
| AREG | amphiregulin | -0.0998748 |
| PTMA | prothymosin, alpha | -0.0994441 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0892664 |
| TMSB10 | thymosin beta 10 | -0.0793846 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0746063 |
| RPS6 | ribosomal protein S6 | -0.0709863 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0704693 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0547648 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0544183 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0541296 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0500502 |
| RPLP1 | ribosomal protein, large, P1 | -0.049336 |
| RPS8 | ribosomal protein S8 | -0.0488386 |
| TXNIP | thioredoxin interacting protein | -0.0476058 |
| RPL12 | ribosomal protein L12 | -0.0466588 |
| RPS19 | ribosomal protein S19 | -0.0442605 |
| EGFR | epidermal growth factor receptor | -0.0437539 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0411182 |
| MT2A | metallothionein 2A | -0.0399723 |
| RPS3 | ribosomal protein S3 | -0.0394074 |
| RPLP0 | ribosomal protein, large, P0 | -0.0390753 |
| RPL11 | ribosomal protein L11 | -0.0367637 |
| S100A10 | S100 calcium binding protein A10 | -0.036724 |
| OXR1 | oxidation resistance 1 | -0.0364918 |
| EZR | ezrin | -0.0357472 |
| RPS4X | ribosomal protein S4, X-linked | -0.0357054 |
| RPL34 | ribosomal protein L34 | -0.0353538 |
| RPL23 | ribosomal protein L23 | -0.034493 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0344282 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0342631 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0334977 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0334446 |
| LDHA | lactate dehydrogenase A | -0.033249 |
| GDF15 | growth differentiation factor 15 | -0.0323912 |
| RPL19 | ribosomal protein L19 | -0.0321044 |
| RPL5 | ribosomal protein L5 | -0.031424 |
| RPL8 | ribosomal protein L8 | -0.0313601 |
| RPS12 | ribosomal protein S12 | -0.0311939 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0311168 |
| RACK1 | receptor for activated C kinase 1 | -0.0306457 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0297044 |
| RPL18 | ribosomal protein L18 | -0.0296697 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0293466 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0288955 |
| UBC | ubiquitin C | -0.0284789 |
| RPL7 | ribosomal protein L7 | -0.0281078 |
| RPS25 | ribosomal protein S25 | -0.0278918 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0275961 |
| RPL35A | ribosomal protein L35a | -0.0274475 |
| PERP | PERP, TP53 apoptosis effector | -0.0272747 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0267623 |
| HLA-B | major histocompatibility complex, class I, B | -0.0266156 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.026538 |
| RPS16 | ribosomal protein S16 | -0.026502 |
| RPS13 | ribosomal protein S13 | -0.0262339 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0261701 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0256776 |
| RPLP2 | ribosomal protein, large, P2 | -0.0254644 |
| RPL36 | ribosomal protein L36 | -0.0252457 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0245882 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0243771 |
| FTL | ferritin, light polypeptide | -0.0240879 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0237192 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0236787 |
| SERINC5 | serine incorporator 5 | -0.0235837 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0234558 |
| RPL28 | ribosomal protein L28 | -0.0234279 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0224397 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0223801 |
| RPS29 | ribosomal protein S29 | -0.022291 |
| FOSL1 | FOS-like antigen 1 | -0.0221955 |
| RPL9 | ribosomal protein L9 | -0.0218557 |
| RPL32 | ribosomal protein L32 | -0.0216565 |
| RPS15 | ribosomal protein S15 | -0.0216098 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0215193 |
| CENPF | centromere protein F, 350/400kDa | -0.0214861 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0214743 |
| GOLGA4 | golgin A4 | -0.0213139 |
| RPL31 | ribosomal protein L31 | -0.0213098 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0212722 |
| RPS5 | ribosomal protein S5 | -0.0211272 |
| MT1X | metallothionein 1X | -0.0206813 |
| NEMF | nuclear export mediator factor | -0.0206696 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 | -0.0202021 |
| RPS23 | ribosomal protein S23 | -0.020055 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0200481 |
| TMEM87A | transmembrane protein 87A | -0.0199542 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0197684 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.0197139 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0196095 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0194714 |
| RPL36A | ribosomal protein L36a | -0.0189695 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0184608 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0182802 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0178721 |
| TUBB | tubulin, beta class I | -0.0178541 |
| CCNI | cyclin I | -0.0177982 |
