Doxycycline Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description Tetracycline in which the 5beta-hydrogen is replaced by a hydroxy group, while the 6alpha-hydroxy group is replaced by hydrogen. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis. (Chemical Entities of Biological Interest Ontology, CHEBI_50845)
External Link http://ctdbase.org/detail.go?type=chem&acc=D004318
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Genes

24 genes/proteins interacting with the chemical Doxycycline from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHR aryl hydrocarbon receptor
ATF2 activating transcription factor 2
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CXCL8 chemokine (C-X-C motif) ligand 8
GSTP1 glutathione S-transferase pi 1
IL1B interleukin 1, beta
MAPK14 mitogen-activated protein kinase 14
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
NOS2 nitric oxide synthase 2, inducible
S1PR1 sphingosine-1-phosphate receptor 1
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SOD1 superoxide dismutase 1, soluble
TARDBP TAR DNA binding protein
TNF tumor necrosis factor