| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Drospirenone perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Drospirenone_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TNIP1 | TNFAIP3 interacting protein 1 | 0.131021 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.126337 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.105261 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.104935 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0977703 |
| FBN1 | fibrillin 1 | 0.0947076 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0917296 |
| PODXL | podocalyxin-like | 0.0766773 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0699938 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0698567 |
| APP | amyloid beta (A4) precursor protein | 0.069204 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0680372 |
| HLA-B | major histocompatibility complex, class I, B | 0.0664382 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0593501 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0581086 |
| SQSTM1 | sequestosome 1 | 0.0580078 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0577137 |
| OPTN | optineurin | 0.0568138 |
| DST | dystonin | 0.0552009 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0531138 |
| B2M | beta-2-microglobulin | 0.0529082 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0516051 |
| COL1A2 | collagen, type I, alpha 2 | 0.0496357 |
| PLEC | plectin | 0.0494916 |
| AUTS2 | autism susceptibility candidate 2 | 0.0468412 |
| FLNA | filamin A, alpha | 0.0468246 |
| C1D | C1D nuclear receptor corepressor | 0.0456339 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0454007 |
| SFTPA2 | surfactant protein A2 | 0.0449954 |
| VEGFA | vascular endothelial growth factor A | 0.0434957 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0412463 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.041042 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0400858 |
| OGA | O-GlcNAcase | 0.0388843 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0384271 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0377145 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0373502 |
| GPC6 | glypican 6 | 0.037113 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0366374 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0361982 |
| LOXL2 | lysyl oxidase-like 2 | 0.0360225 |
| ADAR | adenosine deaminase, RNA-specific | 0.0355908 |
| UBC | ubiquitin C | 0.0354419 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0352353 |
| BSG | basigin (Ok blood group) | 0.0342973 |
| FLNB | filamin B, beta | 0.0339709 |
| NAV2 | neuron navigator 2 | 0.0338335 |
| STC1 | stanniocalcin 1 | 0.0338101 |
| DBN1 | drebrin 1 | 0.0336752 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.033488 |
| NONO | non-POU domain containing, octamer-binding | 0.0330238 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0327344 |
| DSCAM | Down syndrome cell adhesion molecule | 0.032457 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0323756 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0320039 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0317958 |
| SEPTIN9 | septin 9 | 0.031769 |
| PRELID2 | PRELI domain containing 2 | 0.0314962 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0310736 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0308054 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0301903 |
| HLA-C | major histocompatibility complex, class I, C | 0.0296714 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0292166 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0288979 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0288278 |
| MINK1 | misshapen-like kinase 1 | 0.0288178 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0287246 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0286906 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.02854 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.027877 |
| DENND5A | DENN/MADD domain containing 5A | 0.0277117 |
| HDLBP | high density lipoprotein binding protein | 0.0276276 |
| SETD5 | SET domain containing 5 | 0.0275799 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0271371 |
| PLXNA3 | plexin A3 | 0.027092 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0269228 |
| CEP250 | centrosomal protein 250kDa | 0.0267577 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.026737 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0267334 |
| TMSB4X | thymosin beta 4, X-linked | 0.0264826 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0263392 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0260398 |
| PFKP | phosphofructokinase, platelet | 0.0259849 |
| ADM | adrenomedullin | 0.0258986 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0257459 |
| TMOD1 | tropomodulin 1 | 0.0256593 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.0254357 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0249316 |
| MSN | moesin | 0.0249022 |
| CALR | calreticulin | 0.0248526 |
| GOLGA2 | golgin A2 | 0.0245989 |
| SEPTIN2 | septin 2 | 0.0244891 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0242674 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0240884 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0240529 |
| ARRDC3 | arrestin domain containing 3 | 0.0239585 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0237811 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0237622 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0237332 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0237021 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.253266 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.157699 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.15441 |
| CDH13 | cadherin 13 | -0.130626 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0913903 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0856287 |
| FN1 | fibronectin 1 | -0.0853876 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0826538 |
| S100A10 | S100 calcium binding protein A10 | -0.0727194 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0648022 |
| SUCNR1 | succinate receptor 1 | -0.0571567 |
| CCND1 | cyclin D1 | -0.0553105 |
| PLAT | plasminogen activator, tissue | -0.0549766 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0461105 |
| MAP1B | microtubule-associated protein 1B | -0.0450481 |
| LOX | lysyl oxidase | -0.0442248 |
| EFNA5 | ephrin-A5 | -0.0438515 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0422377 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0399468 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0395454 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0387181 |
| POTEF | POTE ankyrin domain family, member F | -0.0383588 |
| LRRC17 | leucine rich repeat containing 17 | -0.0378056 |
| DCLK2 | doublecortin-like kinase 2 | -0.0374989 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0370167 |
| ASPH | aspartate beta-hydroxylase | -0.0367865 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0366123 |
| TPM4 | tropomyosin 4 | -0.0355575 |
| S100A6 | S100 calcium binding protein A6 | -0.0354943 |
| CSTB | cystatin B (stefin B) | -0.035394 |
| CD99 | CD99 molecule | -0.0344753 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0327783 |
| PRSS23 | protease, serine, 23 | -0.0324828 |
| MYADM | myeloid-associated differentiation marker | -0.032449 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0321093 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0320422 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0317887 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0309639 |
| EGFR | epidermal growth factor receptor | -0.0304314 |
| COL3A1 | collagen, type III, alpha 1 | -0.030217 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0300922 |
| SLC39A11 | solute carrier family 39, member 11 | -0.029884 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0291002 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0289023 |
| CENPF | centromere protein F, 350/400kDa | -0.0283477 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0280468 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0279868 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.027359 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0271514 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0270192 |
| LMNA | lamin A/C | -0.0267456 |
| FRMD4A | FERM domain containing 4A | -0.0265084 |
| SEPTIN7 | septin 7 | -0.0253012 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0250364 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0249139 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0248458 |
| IL7R | interleukin 7 receptor | -0.0244353 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0241304 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0231635 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0228575 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0226984 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.022484 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.022044 |
| KRT81 | keratin 81, type II | -0.0219587 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0218219 |
| GNAS | GNAS complex locus | -0.02179 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0212324 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0206461 |
| CEP170 | centrosomal protein 170kDa | -0.0206177 |
| FMN2 | formin 2 | -0.0206166 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0202419 |
| S100A4 | S100 calcium binding protein A4 | -0.0201063 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0198911 |
| RTN4 | reticulon 4 | -0.0198526 |
| CUX1 | cut-like homeobox 1 | -0.0196588 |
| DEK | DEK proto-oncogene | -0.0196539 |
| KIAA1549L | KIAA1549-like | -0.0196026 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0195613 |
| ZNF217 | zinc finger protein 217 | -0.0194103 |
| ACER3 | alkaline ceramidase 3 | -0.0193724 |
| CAVIN1 | caveolae associated protein 1 | -0.0192628 |
| HMGB1 | high mobility group box 1 | -0.0191774 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0191405 |
| SYTL3 | synaptotagmin-like 3 | -0.0191319 |
| AHNAK | AHNAK nucleoprotein | -0.0190731 |
| MEIS2 | Meis homeobox 2 | -0.0188012 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0187934 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0187685 |
| IKBIP | IKBKB interacting protein | -0.018565 |
| CANX | calnexin | -0.0184469 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0183513 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0182813 |
| CDK6 | cyclin-dependent kinase 6 | -0.0182223 |
| DIAPH3 | diaphanous-related formin 3 | -0.0181311 |
| PLXNA2 | plexin A2 | -0.0179155 |
| RPS24 | ribosomal protein S24 | -0.0177831 |
| RIGI | RNA sensor RIG-I | -0.0174744 |
| MTDH | metadherin | -0.0173568 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0172255 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0171161 |
