| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Drospirenone perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Drospirenone_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.125152 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0703645 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0701268 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0662667 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0660414 |
| PCBP2 | poly(rC) binding protein 2 | 0.0635541 |
| RPL3 | ribosomal protein L3 | 0.0605473 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0604706 |
| NONO | non-POU domain containing, octamer-binding | 0.0566807 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0553589 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0488234 |
| CPNE1 | copine I | 0.0449189 |
| YBX3 | Y box binding protein 3 | 0.0439283 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0422761 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0373267 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0372235 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0370222 |
| TPM3 | tropomyosin 3 | 0.0369875 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0361237 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0360169 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0359485 |
| YBX1 | Y box binding protein 1 | 0.0351976 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0347281 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0341562 |
| DST | dystonin | 0.0338523 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.033653 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0336269 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0331463 |
| CCN2 | cellular communication network factor 2 | 0.0322761 |
| RRM2 | ribonucleotide reductase M2 | 0.0321407 |
| CEP250 | centrosomal protein 250kDa | 0.0317407 |
| SET | SET nuclear proto-oncogene | 0.0306441 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0305054 |
| YAP1 | Yes-associated protein 1 | 0.0302891 |
| DBN1 | drebrin 1 | 0.0302703 |
| PLEC | plectin | 0.0287167 |
| HDGF | hepatoma-derived growth factor | 0.0285445 |
| PFN1 | profilin 1 | 0.0276011 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0275088 |
| TMSB10 | thymosin beta 10 | 0.0274379 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0270802 |
| TPI1 | triosephosphate isomerase 1 | 0.0266695 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0264069 |
| CPOX | coproporphyrinogen oxidase | 0.0263849 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0261722 |
| BRD2 | bromodomain containing 2 | 0.0256627 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0251512 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.025111 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0250726 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.0250698 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0248578 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0248135 |
| YEATS2 | YEATS domain containing 2 | 0.0245826 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0242971 |
| INCENP | inner centromere protein antigens 135/155kDa | 0.0242738 |
| CEP192 | centrosomal protein 192kDa | 0.02426 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0238064 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0235999 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0232376 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0230914 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0229621 |
| PDCD6 | programmed cell death 6 | 0.0227756 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.022627 |
| SON | SON DNA binding protein | 0.022613 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0225841 |
| CENPF | centromere protein F, 350/400kDa | 0.0224699 |
| GSE1 | Gse1 coiled-coil protein | 0.0223898 |
| PCM1 | pericentriolar material 1 | 0.0223743 |
| CMIP | c-Maf inducing protein | 0.0223514 |
| EGR1 | early growth response 1 | 0.0222617 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0222567 |
| SFTPA2 | surfactant protein A2 | 0.0220147 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0218521 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0217726 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.02148 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0213171 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0212034 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0210779 |
| SEPTIN2 | septin 2 | 0.0209991 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.020994 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0206254 |
| MSN | moesin | 0.0205832 |
| ACLY | ATP citrate lyase | 0.0205241 |
| DIDO1 | death inducer-obliterator 1 | 0.0202925 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0201961 |
| ADAR | adenosine deaminase, RNA-specific | 0.0199543 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0199124 |
| RPL23 | ribosomal protein L23 | 0.0198594 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0198469 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0198261 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0197285 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0197125 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0195745 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0194889 |
| MSH6 | mutS homolog 6 | 0.0194696 |
| PNN | pinin, desmosome associated protein | 0.0193198 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0192878 |
| BRD4 | bromodomain containing 4 | 0.0192281 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0189131 |
| HLA-A | major histocompatibility complex, class I, A | 0.0188678 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.268352 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.222132 |
| VIM | vimentin | -0.107934 |
| MMP12 | matrix metallopeptidase 12 | -0.102182 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0819993 |
| PCDH7 | protocadherin 7 | -0.0814051 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0689382 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0684682 |
| NLGN1 | neuroligin 1 | -0.0684062 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0623107 |
| ZNF804A | zinc finger protein 804A | -0.059467 |
| CLDN1 | claudin 1 | -0.056589 |
| EHBP1 | EH domain binding protein 1 | -0.0559326 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.053492 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0528403 |
| BCHE | butyrylcholinesterase | -0.0517089 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0515504 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0513498 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0502942 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0502304 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0480796 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0476177 |
| HMGA2 | high mobility group AT-hook 2 | -0.0466125 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0449258 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0443773 |
| JMJD1C | jumonji domain containing 1C | -0.0443415 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0439729 |
| CCND1 | cyclin D1 | -0.0435131 |
| RASAL2 | RAS protein activator like 2 | -0.0432233 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0424504 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0413379 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0411742 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0390862 |
| MTAP | methylthioadenosine phosphorylase | -0.0375952 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0375192 |
| TMEM123 | transmembrane protein 123 | -0.0374494 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.034671 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0345203 |
| KLF6 | Kruppel-like factor 6 | -0.0339498 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0334526 |
| AHNAK | AHNAK nucleoprotein | -0.0333542 |
| MGAT4C | MGAT4 family, member C | -0.0329659 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.0324879 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0312992 |
| VMP1 | vacuole membrane protein 1 | -0.0304989 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.030395 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0298653 |
| CANX | calnexin | -0.0284404 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0284123 |
| CDK17 | cyclin-dependent kinase 17 | -0.0283144 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0282915 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0278873 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0277865 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.027723 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0275882 |
| NABP1 | nucleic acid binding protein 1 | -0.0275628 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0265654 |
| GPHN | gephyrin | -0.0263997 |
| GNAS | GNAS complex locus | -0.0261396 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0261094 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0258527 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0253353 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0251592 |
| RPS8 | ribosomal protein S8 | -0.0244281 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0243739 |
| SYT1 | synaptotagmin I | -0.0243055 |
| RPL26 | ribosomal protein L26 | -0.0242524 |
| MAP4 | microtubule-associated protein 4 | -0.0242036 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0241071 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0238551 |
| NF1 | neurofibromin 1 | -0.0237746 |
| RPS2 | ribosomal protein S2 | -0.0237505 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0234988 |
| RPS27A | ribosomal protein S27a | -0.0233633 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0233211 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0230792 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0225996 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0224215 |
| ZNF217 | zinc finger protein 217 | -0.0222663 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0222633 |
| EDN1 | endothelin 1 | -0.022196 |
| RPS24 | ribosomal protein S24 | -0.0216694 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0215035 |
| ERBIN | erbb2 interacting protein | -0.0212912 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0212453 |
| MYPN | myopalladin | -0.0209968 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0209213 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0207329 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0207322 |
| HMGB1 | high mobility group box 1 | -0.0206235 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0206016 |
| BPTF | bromodomain PHD finger transcription factor | -0.0204683 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0204355 |
| LMO7 | LIM domain 7 | -0.0204271 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0202216 |
| IPO7 | importin 7 | -0.0201138 |
| RPL34 | ribosomal protein L34 | -0.0199771 |
| SBF2 | SET binding factor 2 | -0.0198944 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0194248 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0191867 |
