| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Drospirenone perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Drospirenone_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.149779 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.112422 |
| VEGFA | vascular endothelial growth factor A | 0.0861324 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0832178 |
| VCL | vinculin | 0.0812462 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0690116 |
| ACTG1 | actin gamma 1 | 0.0689392 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0626306 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0615996 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0564831 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0558936 |
| NONO | non-POU domain containing, octamer-binding | 0.0531525 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0517907 |
| RPL3 | ribosomal protein L3 | 0.0459537 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0455455 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0451213 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0438078 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0437578 |
| CRH | corticotropin releasing hormone | 0.0428361 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0406446 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0402031 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0396867 |
| PTMA | prothymosin, alpha | 0.0388634 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0385763 |
| RPL19 | ribosomal protein L19 | 0.0364592 |
| TPM1 | tropomyosin 1 (alpha) | 0.0363607 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0361718 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0359615 |
| VGF | VGF nerve growth factor inducible | 0.035851 |
| RPL23 | ribosomal protein L23 | 0.0354793 |
| TLE4 | transducin-like enhancer of split 4 | 0.0350928 |
| LMNA | lamin A/C | 0.0341686 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0340943 |
| SEPTIN9 | septin 9 | 0.0339357 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0338316 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0335823 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0334688 |
| DST | dystonin | 0.033448 |
| EGR1 | early growth response 1 | 0.0328277 |
| AMOTL1 | angiomotin like 1 | 0.032668 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0317222 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0313112 |
| RPL4 | ribosomal protein L4 | 0.0312035 |
| RARA | retinoic acid receptor, alpha | 0.030811 |
| ACTN1 | actinin, alpha 1 | 0.0304377 |
| APP | amyloid beta (A4) precursor protein | 0.0303115 |
| B2M | beta-2-microglobulin | 0.0296284 |
| RPL37A | ribosomal protein L37a | 0.0293908 |
| LPIN1 | lipin 1 | 0.0288216 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0287268 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0285586 |
| SET | SET nuclear proto-oncogene | 0.0283906 |
| FAM107B | family with sequence similarity 107, member B | 0.027201 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0267377 |
| CEP250 | centrosomal protein 250kDa | 0.0264866 |
| FNBP1 | formin binding protein 1 | 0.0259961 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0259527 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0255169 |
| PGK1 | phosphoglycerate kinase 1 | 0.0253534 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.0252472 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0251769 |
| PLEC | plectin | 0.0251617 |
| RPL7 | ribosomal protein L7 | 0.0249946 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0247791 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0246034 |
| TBX2 | T-box 2 | 0.0245485 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 | 0.0245479 |
| FAM13A | family with sequence similarity 13, member A | 0.0244498 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0241251 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0240901 |
| TRIB2 | tribbles pseudokinase 2 | 0.0239747 |
| FUS | FUS RNA binding protein | 0.0234533 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0233926 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0233779 |
| HLA-C | major histocompatibility complex, class I, C | 0.0232631 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0232115 |
| SCRN1 | secernin 1 | 0.0230125 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.022901 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0228916 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0227976 |
| FLNA | filamin A, alpha | 0.0227945 |
| RNF213 | ring finger protein 213 | 0.0227918 |
| DBN1 | drebrin 1 | 0.0227248 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | 0.0221487 |
| STK38L | serine/threonine kinase 38 like | 0.0221415 |
| RPL35A | ribosomal protein L35a | 0.0221199 |
| PFKP | phosphofructokinase, platelet | 0.0220572 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0220373 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0219491 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0219269 |
| RACK1 | receptor for activated C kinase 1 | 0.0218596 |
| RPS27 | ribosomal protein S27 | 0.0218492 |
| DUSP10 | dual specificity phosphatase 10 | 0.0218438 |
| NDRG1 | N-myc downstream regulated 1 | 0.0217056 |
| ADAR | adenosine deaminase, RNA-specific | 0.021496 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0214421 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0214146 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0211258 |
| MEF2D | myocyte enhancer factor 2D | 0.0210689 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0210541 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.18842 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.174347 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.159766 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.074305 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0648559 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0637112 |
| MEIS2 | Meis homeobox 2 | -0.0636058 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.063335 |
| LSAMP | limbic system-associated membrane protein | -0.062569 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0625249 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0599226 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0588887 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0547795 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0543772 |
| COL3A1 | collagen, type III, alpha 1 | -0.0470855 |
| ZNF804A | zinc finger protein 804A | -0.0465714 |
| ZNF292 | zinc finger protein 292 | -0.0464325 |
| SYT1 | synaptotagmin I | -0.0427505 |
| JMJD1C | jumonji domain containing 1C | -0.0405634 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0377996 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.037712 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.03756 |
| GPC5 | glypican 5 | -0.0374163 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0373559 |
| USP34 | ubiquitin specific peptidase 34 | -0.0363941 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.035539 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.035417 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0350839 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0344082 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0341269 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0339042 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0325622 |
| CADM2 | cell adhesion molecule 2 | -0.0324996 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0323263 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0318906 |
| PCDH9 | protocadherin 9 | -0.0316899 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0316761 |
| NBEA | neurobeachin | -0.0313475 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0308326 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0305424 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0304838 |
| CCND1 | cyclin D1 | -0.0300444 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0299993 |
| GOLGA4 | golgin A4 | -0.0299664 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.029296 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0292192 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0292152 |
| NEK7 | NIMA-related kinase 7 | -0.029191 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0288181 |
| VIM | vimentin | -0.0284694 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0284645 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0281817 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0281771 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0280439 |
| ATRNL1 | attractin-like 1 | -0.0276429 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0273955 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0271398 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.027109 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0270672 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0268102 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0265331 |
| KLHL13 | kelch-like family member 13 | -0.0265122 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0264004 |
| FHIT | fragile histidine triad | -0.0260045 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0257008 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.025609 |
| SBF2 | SET binding factor 2 | -0.0255714 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0255325 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0255256 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0252905 |
| PTK2 | protein tyrosine kinase 2 | -0.025024 |
| IER3 | immediate early response 3 | -0.0247369 |
| TBC1D19 | TBC1 domain family, member 19 | -0.0245327 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0243608 |
| MAP4 | microtubule-associated protein 4 | -0.024082 |
| USP3 | ubiquitin specific peptidase 3 | -0.023687 |
| GNAS | GNAS complex locus | -0.0235277 |
| YME1L1 | YME1-like 1 ATPase | -0.0231975 |
| DSTN | destrin (actin depolymerizing factor) | -0.0231638 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0227941 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0226939 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0225307 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0224677 |
| CEP95 | centrosomal protein 95kDa | -0.0224494 |
| RAI14 | retinoic acid induced 14 | -0.0223441 |
| ZFR | zinc finger RNA binding protein | -0.0222995 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0221048 |
| PRR11 | proline rich 11 | -0.0219037 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0216842 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0216683 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0213587 |
| CDC27 | cell division cycle 27 | -0.0213438 |
| HIP1 | huntingtin interacting protein 1 | -0.0212874 |
| FRMD4A | FERM domain containing 4A | -0.0211305 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0210808 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0206318 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | -0.0205671 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0205208 |
| MTDH | metadherin | -0.0201494 |
| ERBIN | erbb2 interacting protein | -0.0200871 |
