| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Drospirenone perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Drospirenone_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.174725 |
| FLNB | filamin B, beta | 0.149669 |
| PLEC | plectin | 0.143219 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.126402 |
| PODXL | podocalyxin-like | 0.108935 |
| KRT17 | keratin 17, type I | 0.095644 |
| TMSB4X | thymosin beta 4, X-linked | 0.0790206 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0714632 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0706833 |
| KRT6A | keratin 6A, type II | 0.0683421 |
| EFHD2 | EF-hand domain family, member D2 | 0.0652352 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0651478 |
| FLNA | filamin A, alpha | 0.0629321 |
| MSN | moesin | 0.0609466 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0553816 |
| NCOR2 | nuclear receptor corepressor 2 | 0.054017 |
| OGA | O-GlcNAcase | 0.0530314 |
| KRT14 | keratin 14, type I | 0.0508174 |
| RPL3 | ribosomal protein L3 | 0.050244 |
| CPNE1 | copine I | 0.0485064 |
| LMNA | lamin A/C | 0.0475999 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0461915 |
| NONO | non-POU domain containing, octamer-binding | 0.0461869 |
| BLCAP | bladder cancer associated protein | 0.0459724 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0434768 |
| CEP250 | centrosomal protein 250kDa | 0.0422738 |
| APP | amyloid beta (A4) precursor protein | 0.0421616 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0418212 |
| EZR | ezrin | 0.041207 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0411632 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0410073 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0394365 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0382565 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.037471 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0370689 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0360654 |
| LAMA5 | laminin, alpha 5 | 0.0359169 |
| PGK1 | phosphoglycerate kinase 1 | 0.035778 |
| YBX3 | Y box binding protein 3 | 0.0351108 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0347348 |
| BCL2L1 | BCL2-like 1 | 0.0342377 |
| ANXA1 | annexin A1 | 0.0328629 |
| MED15 | mediator complex subunit 15 | 0.0326259 |
| HLA-C | major histocompatibility complex, class I, C | 0.0324814 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0324012 |
| TGM2 | transglutaminase 2 | 0.0321862 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0321568 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0319575 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0317064 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0316596 |
| DIDO1 | death inducer-obliterator 1 | 0.0311026 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0310572 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0307338 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0298911 |
| SDC4 | syndecan 4 | 0.0291745 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0282592 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0281231 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0280276 |
| DSCAM | Down syndrome cell adhesion molecule | 0.027552 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0275393 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.026949 |
| SMAD3 | SMAD family member 3 | 0.0267756 |
| EMP1 | epithelial membrane protein 1 | 0.0266235 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0266096 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0265425 |
| RASA3 | RAS p21 protein activator 3 | 0.0264493 |
| PRELID3B | PRELI domain containing 3B | 0.0260746 |
| RLIM | ring finger protein, LIM domain interacting | 0.0258898 |
| GUK1 | guanylate kinase 1 | 0.0258816 |
| MYOF | myoferlin | 0.0256968 |
| SQLE | squalene epoxidase | 0.0254361 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0253579 |
| RBM39 | RNA binding motif protein 39 | 0.0251053 |
| PTMA | prothymosin, alpha | 0.024936 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.024873 |
| SERINC3 | serine incorporator 3 | 0.02471 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0246415 |
| KRT8 | keratin 8, type II | 0.0245444 |
| APOL2 | apolipoprotein L, 2 | 0.0244421 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0237462 |
| SPAG9 | sperm associated antigen 9 | 0.02372 |
| YBX1 | Y box binding protein 1 | 0.0236465 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0234495 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0233587 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0224011 |
| AFAP1 | actin filament associated protein 1 | 0.0221463 |
| MT1X | metallothionein 1X | 0.0221223 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0220778 |
| MYO10 | myosin X | 0.0218274 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0217097 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0216831 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0215805 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0214675 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0214512 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.0213594 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0213432 |
| MORF4L2 | mortality factor 4 like 2 | 0.021267 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0211372 |
| CLTB | clathrin, light chain B | 0.0211351 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0210497 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.237455 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.195742 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.182425 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.076785 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0741084 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0683054 |
| MTSS1 | metastasis suppressor 1 | -0.0671742 |
| RPS8 | ribosomal protein S8 | -0.0663339 |
| MT2A | metallothionein 2A | -0.066205 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0661948 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0655224 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0640065 |
| RPS6 | ribosomal protein S6 | -0.0620087 |
| CD44 | CD44 molecule (Indian blood group) | -0.0613874 |
| POTEF | POTE ankyrin domain family, member F | -0.0585475 |
| S100A10 | S100 calcium binding protein A10 | -0.0542546 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0514906 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0488471 |
| RPLP2 | ribosomal protein, large, P2 | -0.0471871 |
| GNAS | GNAS complex locus | -0.0464092 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0447681 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0420964 |
| RPS13 | ribosomal protein S13 | -0.0418884 |
| RPS23 | ribosomal protein S23 | -0.0414323 |
| CDK6 | cyclin-dependent kinase 6 | -0.041312 |
| OSMR | oncostatin M receptor | -0.0399086 |
| ENO1 | enolase 1, (alpha) | -0.0392493 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0392102 |
| HMGA2 | high mobility group AT-hook 2 | -0.0389589 |
| RAI14 | retinoic acid induced 14 | -0.0380175 |
| PALLD | palladin, cytoskeletal associated protein | -0.0374399 |
| RPS19 | ribosomal protein S19 | -0.0371132 |
| RPS12 | ribosomal protein S12 | -0.0367811 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0367588 |
| PRSS23 | protease, serine, 23 | -0.0359602 |
| B2M | beta-2-microglobulin | -0.0358645 |
| RPS25 | ribosomal protein S25 | -0.0358207 |
| RASAL2 | RAS protein activator like 2 | -0.0356902 |
| RPS15 | ribosomal protein S15 | -0.0350298 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0344951 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0342108 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0340247 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0336316 |
| RPL8 | ribosomal protein L8 | -0.033018 |
| RPLP1 | ribosomal protein, large, P1 | -0.0324737 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0321293 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0320886 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0319593 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0314265 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0307871 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0307324 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0306716 |
| RPL12 | ribosomal protein L12 | -0.0305598 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.030297 |
| RPL30 | ribosomal protein L30 | -0.0302675 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0299705 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0299501 |
| RPL32 | ribosomal protein L32 | -0.0295787 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0288997 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0281298 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0279762 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0279659 |
| CLU | clusterin | -0.0279377 |
| RPS29 | ribosomal protein S29 | -0.0278342 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0277428 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0273074 |
| RPL34 | ribosomal protein L34 | -0.0269324 |
| JMJD1C | jumonji domain containing 1C | -0.0267785 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0267158 |
| EFNA5 | ephrin-A5 | -0.0266383 |
| HMGA1 | high mobility group AT-hook 1 | -0.0265786 |
| CDCP1 | CUB domain containing protein 1 | -0.0263619 |
| HM13 | histocompatibility (minor) 13 | -0.0261991 |
| RAD51B | RAD51 paralog B | -0.0261738 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0260759 |
| RPS24 | ribosomal protein S24 | -0.0257641 |
| RPL37A | ribosomal protein L37a | -0.0257183 |
| STC1 | stanniocalcin 1 | -0.0253627 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0251211 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0249695 |
| RPL5 | ribosomal protein L5 | -0.024852 |
| S100A9 | S100 calcium binding protein A9 | -0.0247315 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.024384 |
| EGFR | epidermal growth factor receptor | -0.0241812 |
| LMO7 | LIM domain 7 | -0.0240859 |
| MTAP | methylthioadenosine phosphorylase | -0.0238917 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0237446 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0236633 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.023608 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0235723 |
| DOK5 | docking protein 5 | -0.0234377 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0233984 |
| RPS21 | ribosomal protein S21 | -0.0230263 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0229304 |
| FOXP1 | forkhead box P1 | -0.0228028 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0224826 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0224096 |
| FTL | ferritin, light polypeptide | -0.0224073 |
| RPS11 | ribosomal protein S11 | -0.0222612 |
| RPL9 | ribosomal protein L9 | -0.0221799 |
