| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Drospirenone perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Drospirenone_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.231417 |
| KRT8 | keratin 8, type II | 0.228093 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.151984 |
| KRT18 | keratin 18, type I | 0.141274 |
| VEGFA | vascular endothelial growth factor A | 0.126454 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.109969 |
| FAT1 | FAT atypical cadherin 1 | 0.109833 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.107908 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0885402 |
| RPL3 | ribosomal protein L3 | 0.0839381 |
| TNS4 | tensin 4 | 0.0809541 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0707264 |
| ITGA6 | integrin, alpha 6 | 0.0701461 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0683172 |
| TMSB10 | thymosin beta 10 | 0.0679617 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0659489 |
| ABHD2 | abhydrolase domain containing 2 | 0.0649607 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0629801 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0608922 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0566154 |
| DSPP | dentin sialophosphoprotein | 0.0529091 |
| TMSB4X | thymosin beta 4, X-linked | 0.0528472 |
| PLEC | plectin | 0.0526463 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.051479 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.049429 |
| FLNB | filamin B, beta | 0.049069 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0480899 |
| ACTN4 | actinin, alpha 4 | 0.0479152 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0477894 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0474503 |
| MINK1 | misshapen-like kinase 1 | 0.0473297 |
| NONO | non-POU domain containing, octamer-binding | 0.0464251 |
| ANXA11 | annexin A11 | 0.0460625 |
| EZR | ezrin | 0.0455912 |
| MLEC | malectin | 0.045026 |
| LMO7 | LIM domain 7 | 0.044809 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0433397 |
| RNF43 | ring finger protein 43 | 0.0414885 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0404414 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0402072 |
| CD9 | CD9 molecule | 0.0398464 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0393149 |
| CTBP2 | C-terminal binding protein 2 | 0.0380844 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0373359 |
| YBX1 | Y box binding protein 1 | 0.0370738 |
| RPL23 | ribosomal protein L23 | 0.0366015 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0364279 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0361485 |
| ASPH | aspartate beta-hydroxylase | 0.0361023 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0355552 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0353316 |
| MYO5B | myosin VB | 0.0348202 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0343979 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.03416 |
| DNM2 | dynamin 2 | 0.0335718 |
| HRNR | hornerin | 0.0332259 |
| EPHA2 | EPH receptor A2 | 0.0330154 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0327918 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0311974 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0309295 |
| AREG | amphiregulin | 0.0308456 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0302978 |
| CADPS | Ca++-dependent secretion activator | 0.0301589 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0301029 |
| INSIG1 | insulin induced gene 1 | 0.029914 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0292084 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0291386 |
| CALR | calreticulin | 0.0291155 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0290997 |
| GPA33 | glycoprotein A33 (transmembrane) | 0.0287939 |
| GAK | cyclin G associated kinase | 0.0281186 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0281065 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0278691 |
| RPL11 | ribosomal protein L11 | 0.0271538 |
| ACTG1 | actin gamma 1 | 0.0269859 |
| PCBP2 | poly(rC) binding protein 2 | 0.0269186 |
| CPNE1 | copine I | 0.0268235 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0265231 |
| ITGB4 | integrin, beta 4 | 0.0264893 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0263181 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0262581 |
| SON | SON DNA binding protein | 0.0261468 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0256057 |
| MXD1 | MAX dimerization protein 1 | 0.0255759 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0251821 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0251449 |
| TPM3 | tropomyosin 3 | 0.0248852 |
| LMNA | lamin A/C | 0.0248436 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0246374 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0245861 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0244009 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0243919 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0240257 |
| GUK1 | guanylate kinase 1 | 0.0238975 |
| PNN | pinin, desmosome associated protein | 0.0236785 |
| HDAC4 | histone deacetylase 4 | 0.0236481 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.0236473 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0235934 |
| MLPH | melanophilin | 0.0233524 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0232247 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.220904 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.192544 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0921706 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0914731 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0891088 |
| NPSR1 | neuropeptide S receptor 1 | -0.0646321 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0624738 |
| GOLGA4 | golgin A4 | -0.040364 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0382799 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0358694 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0355958 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0339156 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0325419 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0313065 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0296468 |
| AGR2 | anterior gradient 2 | -0.0289008 |
| JMJD1C | jumonji domain containing 1C | -0.0287028 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0283192 |
| RPS2 | ribosomal protein S2 | -0.0279477 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0277929 |
| RPS24 | ribosomal protein S24 | -0.0276758 |
| EREG | epiregulin | -0.0273207 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0264889 |
| CCND1 | cyclin D1 | -0.0259348 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0254721 |
| MAP4 | microtubule-associated protein 4 | -0.0252209 |
| H1-0 | H1.0 linker histone | -0.0247082 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0246591 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0245278 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.024427 |
| HMGB1 | high mobility group box 1 | -0.0244128 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0241168 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0233763 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0232254 |
| CANX | calnexin | -0.0230682 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0230441 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0229386 |
| COG5 | component of oligomeric golgi complex 5 | -0.0223259 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0221091 |
| SBF2 | SET binding factor 2 | -0.022107 |
| ZNF33A | zinc finger protein 33A | -0.0216344 |
| SEC24D | SEC24 family member D | -0.0214465 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0214137 |
| DEK | DEK proto-oncogene | -0.0210196 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0209824 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0209439 |
| CD2AP | CD2-associated protein | -0.0206947 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0206067 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0205588 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0205504 |
| IER3 | immediate early response 3 | -0.0204799 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0202262 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0201388 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0199196 |
| SRP72 | signal recognition particle 72kDa | -0.0198233 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0197013 |
| RPS8 | ribosomal protein S8 | -0.0193264 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0190492 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0189446 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0185448 |
| POF1B | premature ovarian failure, 1B | -0.018516 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0184089 |
| ZNF292 | zinc finger protein 292 | -0.0183714 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0182064 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0181969 |
| MTDH | metadherin | -0.0181506 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0178568 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0175194 |
| CCNI | cyclin I | -0.0174878 |
| GNAS | GNAS complex locus | -0.0171993 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0171724 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0171681 |
| WASF2 | WAS protein family, member 2 | -0.017105 |
| TMEM123 | transmembrane protein 123 | -0.0168174 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0168074 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0167829 |
| NF1 | neurofibromin 1 | -0.0166511 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0165521 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0164928 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0163934 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0163024 |
| RTN3 | reticulon 3 | -0.016283 |
| USP3 | ubiquitin specific peptidase 3 | -0.0162605 |
| TCF12 | transcription factor 12 | -0.0160959 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.016085 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0158997 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0158599 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0158494 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0157404 |
| TMEM263 | transmembrane protein 263 | -0.0156683 |
| USP53 | ubiquitin specific peptidase 53 | -0.0156285 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0156183 |
| RPL14 | ribosomal protein L14 | -0.015607 |
| AHNAK | AHNAK nucleoprotein | -0.0155077 |
| PRSS3 | protease, serine, 3 | -0.0155076 |
| FHIT | fragile histidine triad | -0.0155063 |
| NFIA | nuclear factor I/A | -0.0153868 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.015371 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0153598 |
| FRMD5 | FERM domain containing 5 | -0.0152803 |
