| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Drospirenone perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Drospirenone_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.151455 |
| TMSB4X | thymosin beta 4, X-linked | 0.15004 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0878929 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0867909 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0865733 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0840891 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0834422 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0820093 |
| APP | amyloid beta (A4) precursor protein | 0.0797291 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0736998 |
| ACTG1 | actin gamma 1 | 0.0735185 |
| TXNRD1 | thioredoxin reductase 1 | 0.0686385 |
| NONO | non-POU domain containing, octamer-binding | 0.0652478 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0638095 |
| CENPF | centromere protein F, 350/400kDa | 0.0625767 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0531726 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0528293 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0522948 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.05048 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.048209 |
| AHNAK | AHNAK nucleoprotein | 0.0478408 |
| RPL3 | ribosomal protein L3 | 0.0467366 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0455422 |
| PODXL | podocalyxin-like | 0.0453893 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.044531 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0444857 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0443424 |
| RAI1 | retinoic acid induced 1 | 0.044166 |
| CAPRIN2 | caprin family member 2 | 0.0440953 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0439727 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0436045 |
| PLEC | plectin | 0.0426074 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0423528 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0416573 |
| PGK1 | phosphoglycerate kinase 1 | 0.0410875 |
| SET | SET nuclear proto-oncogene | 0.0404928 |
| YBX3 | Y box binding protein 3 | 0.0400862 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0398895 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0395911 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0394876 |
| SMAD3 | SMAD family member 3 | 0.0386377 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0382826 |
| HDLBP | high density lipoprotein binding protein | 0.0381005 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0380095 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0379732 |
| MKI67 | marker of proliferation Ki-67 | 0.0371315 |
| YBX1 | Y box binding protein 1 | 0.0365927 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0360086 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0359914 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0355869 |
| OGA | O-GlcNAcase | 0.0355668 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0355322 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0353674 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0353514 |
| TOP1 | topoisomerase (DNA) I | 0.0352274 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0341773 |
| CMIP | c-Maf inducing protein | 0.0341429 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0340391 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0337999 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0337149 |
| FLNB | filamin B, beta | 0.0337127 |
| SON | SON DNA binding protein | 0.033487 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.033447 |
| ACTN1 | actinin, alpha 1 | 0.0332023 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0331624 |
| PUM1 | pumilio RNA-binding family member 1 | 0.032521 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0325086 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0324029 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0323025 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0322227 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0318131 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0313133 |
| SPAG9 | sperm associated antigen 9 | 0.0308445 |
| LDHA | lactate dehydrogenase A | 0.030749 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0305164 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0299618 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0298976 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0298347 |
| PLK2 | polo-like kinase 2 | 0.0296049 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0294944 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.029327 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0291135 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0290014 |
| CEP250 | centrosomal protein 250kDa | 0.0289808 |
| MOK | MOK protein kinase | 0.0289419 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0288379 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0288306 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0287912 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0284957 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0283417 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0281407 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0281231 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0273569 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0272525 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0271223 |
| DENND5A | DENN/MADD domain containing 5A | 0.027027 |
| STAG2 | stromal antigen 2 | 0.0270235 |
| JUN | jun proto-oncogene | 0.026889 |
| RGS4 | regulator of G-protein signaling 4 | 0.0268856 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0267352 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.383842 |
| TP63 | tumor protein p63 | -0.106274 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0969972 |
| VIM | vimentin | -0.0950687 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0755121 |
| CADM2 | cell adhesion molecule 2 | -0.0644865 |
| HMGA1 | high mobility group AT-hook 1 | -0.063133 |
| EFNA5 | ephrin-A5 | -0.0620961 |
| CD44 | CD44 molecule (Indian blood group) | -0.06154 |
| POTEF | POTE ankyrin domain family, member F | -0.0569618 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0555605 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0553435 |
| RPS6 | ribosomal protein S6 | -0.053395 |
| RPS8 | ribosomal protein S8 | -0.0498941 |
| RPS12 | ribosomal protein S12 | -0.0489665 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.047793 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0470085 |
| MT2A | metallothionein 2A | -0.0468971 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0431943 |
| RPS23 | ribosomal protein S23 | -0.042316 |
| RPL37A | ribosomal protein L37a | -0.0422656 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0409069 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0408636 |
| HLA-B | major histocompatibility complex, class I, B | -0.0400395 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0381777 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.037599 |
| RPL31 | ribosomal protein L31 | -0.0374026 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0350965 |
| FTL | ferritin, light polypeptide | -0.0348073 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0347286 |
| RPS29 | ribosomal protein S29 | -0.0344559 |
| RPL35A | ribosomal protein L35a | -0.0337629 |
| EPHA4 | EPH receptor A4 | -0.0329839 |
| TNS3 | tensin 3 | -0.0326624 |
| RPLP2 | ribosomal protein, large, P2 | -0.0319919 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0305334 |
| HLA-A | major histocompatibility complex, class I, A | -0.0304348 |
| RPL12 | ribosomal protein L12 | -0.0299609 |
| RPLP1 | ribosomal protein, large, P1 | -0.0289122 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0286346 |
| PRELID2 | PRELI domain containing 2 | -0.0279807 |
| RPL36 | ribosomal protein L36 | -0.0277186 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0273404 |
| RPS10 | ribosomal protein S10 | -0.027299 |
| RPS25 | ribosomal protein S25 | -0.0266397 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.026466 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0259421 |
| SRGN | serglycin | -0.0258349 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.025441 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0251137 |
| RPL9 | ribosomal protein L9 | -0.0250782 |
| RPL28 | ribosomal protein L28 | -0.0250188 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.024973 |
| SP100 | SP100 nuclear antigen | -0.0247322 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0246926 |
| RPS15 | ribosomal protein S15 | -0.0245694 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0244245 |
| EHBP1 | EH domain binding protein 1 | -0.024409 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0240514 |
| PDE10A | phosphodiesterase 10A | -0.0240299 |
| RPS2 | ribosomal protein S2 | -0.0238836 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0238093 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0237847 |
| RPS13 | ribosomal protein S13 | -0.0234681 |
| RPS19 | ribosomal protein S19 | -0.0232992 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0229282 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0224667 |
| TXNIP | thioredoxin interacting protein | -0.0224638 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0217665 |
| PLIN2 | perilipin 2 | -0.0216489 |
| B2M | beta-2-microglobulin | -0.0216356 |
| RPL27 | ribosomal protein L27 | -0.0213057 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0212389 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0208994 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.020745 |
| MEF2A | myocyte enhancer factor 2A | -0.0206486 |
| RPS11 | ribosomal protein S11 | -0.020466 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.020235 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0199712 |
| ECE1 | endothelin converting enzyme 1 | -0.0197361 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.019632 |
| GOLGA4 | golgin A4 | -0.0195679 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0193166 |
| TAPBP | TAP binding protein (tapasin) | -0.0192887 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0190475 |
| MT1E | metallothionein 1E | -0.0188906 |
| GNAS | GNAS complex locus | -0.0188711 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0184608 |
| RPL34 | ribosomal protein L34 | -0.018326 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0181364 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0180931 |
| RPL26 | ribosomal protein L26 | -0.018036 |
| RPL36A | ribosomal protein L36a | -0.0180051 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0179948 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0177069 |
| RPL38 | ribosomal protein L38 | -0.0175988 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0174094 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0172078 |
| RPS27A | ribosomal protein S27a | -0.0171154 |
| RPS17 | ribosomal protein S17 | -0.0171038 |
