| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Drospirenone perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Drospirenone_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOC112694756 | uncharaterized LOC112694756 | 0.112894 |
| TMSB10 | thymosin beta 10 | 0.106641 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0814316 |
| PLEC | plectin | 0.0759607 |
| GRAMD1B | GRAM domain containing 1B | 0.0711857 |
| MT2A | metallothionein 2A | 0.0630663 |
| KRT18 | keratin 18, type I | 0.0630049 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0607878 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0542152 |
| LAMA4 | laminin, alpha 4 | 0.051354 |
| SEC61G | Sec61 gamma subunit | 0.0495569 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0479658 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0458456 |
| RPL35A | ribosomal protein L35a | 0.0438606 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0429316 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0395331 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0374837 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0354902 |
| SMAD3 | SMAD family member 3 | 0.0345128 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0340543 |
| HSPA8 | heat shock 70kDa protein 8 | 0.033725 |
| RPL3 | ribosomal protein L3 | 0.0333089 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0331343 |
| KRT8 | keratin 8, type II | 0.033091 |
| LAMC2 | laminin, gamma 2 | 0.0329861 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0324402 |
| MT1X | metallothionein 1X | 0.0322732 |
| HYOU1 | hypoxia up-regulated 1 | 0.0321446 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0315482 |
| VCL | vinculin | 0.0312316 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0308816 |
| GUK1 | guanylate kinase 1 | 0.030844 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0295184 |
| RPL11 | ribosomal protein L11 | 0.0292745 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0290888 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0290643 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.028946 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0287643 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0285094 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0281423 |
| AREG | amphiregulin | 0.028072 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0280675 |
| RPLP1 | ribosomal protein, large, P1 | 0.0267882 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0259485 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0259369 |
| ACTG1 | actin gamma 1 | 0.0256246 |
| PGK1 | phosphoglycerate kinase 1 | 0.0255828 |
| RHOV | ras homolog family member V | 0.0252751 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0252093 |
| YBX3 | Y box binding protein 3 | 0.0244365 |
| FTL | ferritin, light polypeptide | 0.0243876 |
| PDE8A | phosphodiesterase 8A | 0.0241882 |
| RPS19 | ribosomal protein S19 | 0.0241061 |
| NONO | non-POU domain containing, octamer-binding | 0.0238957 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0236353 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0227327 |
| RPL37 | ribosomal protein L37 | 0.022475 |
| PYGL | phosphorylase, glycogen, liver | 0.0223769 |
| OSTC | oligosaccharyltransferase complex subunit (non-catalytic) | 0.0223762 |
| RPS27 | ribosomal protein S27 | 0.0223575 |
| B2M | beta-2-microglobulin | 0.0222021 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0220685 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0219511 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0218603 |
| HLA-B | major histocompatibility complex, class I, B | 0.0216326 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0215567 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0214144 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.021169 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0211231 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0209254 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0206773 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0204841 |
| SMTN | smoothelin | 0.020479 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0195189 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0194918 |
| SEPTIN10 | septin 10 | 0.0194623 |
| RNF213 | ring finger protein 213 | 0.0192996 |
| RPS6 | ribosomal protein S6 | 0.0192669 |
| MAP7 | microtubule-associated protein 7 | 0.0188273 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0187771 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0187554 |
| ACTN1 | actinin, alpha 1 | 0.0182784 |
| CST3 | cystatin C | 0.0181827 |
| EGR1 | early growth response 1 | 0.018145 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0180651 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0180272 |
| BMP6 | bone morphogenetic protein 6 | 0.0178505 |
| SQOR | sulfide quinone oxidoreductase | 0.0178108 |
| MSN | moesin | 0.0177206 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0176852 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0176545 |
| RPS14 | ribosomal protein S14 | 0.0175215 |
| SLTM | SAFB-like, transcription modulator | 0.0175066 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0174318 |
| STC1 | stanniocalcin 1 | 0.0173429 |
| PFKP | phosphofructokinase, platelet | 0.01712 |
| WDR1 | WD repeat domain 1 | 0.0170198 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0169852 |
| TJP1 | tight junction protein 1 | 0.0166349 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0165592 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.353134 |
| EGFR | epidermal growth factor receptor | -0.283455 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.204239 |
| TXNRD1 | thioredoxin reductase 1 | -0.18798 |
| UBC | ubiquitin C | -0.0787916 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0687162 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0616098 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0559069 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0544631 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0530826 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0522476 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0499755 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0485704 |
| CANX | calnexin | -0.0480114 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0477091 |
| TMEM165 | transmembrane protein 165 | -0.0473452 |
| USP34 | ubiquitin specific peptidase 34 | -0.0471277 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0455707 |
| WASF2 | WAS protein family, member 2 | -0.0436754 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0422362 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0418141 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.041253 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0412497 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0379568 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0367856 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0361989 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0356236 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.035364 |
| ASPH | aspartate beta-hydroxylase | -0.0350976 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0343536 |
| PAPOLA | poly(A) polymerase alpha | -0.0342893 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0341733 |
| GOLGB1 | golgin B1 | -0.0331382 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0326913 |
| ZNF638 | zinc finger protein 638 | -0.0326102 |
| NDRG1 | N-myc downstream regulated 1 | -0.0316287 |
| AHNAK | AHNAK nucleoprotein | -0.0310438 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.030615 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0300995 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.029836 |
| CCNI | cyclin I | -0.0296946 |
| PKM | pyruvate kinase, muscle | -0.0291763 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0289295 |
| PCBP2 | poly(rC) binding protein 2 | -0.0288241 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0279235 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0278611 |
| SUCO | SUN domain containing ossification factor | -0.0277016 |
| JMJD1C | jumonji domain containing 1C | -0.0275704 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0271337 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0270899 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0270717 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0269175 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0259 |
| USP53 | ubiquitin specific peptidase 53 | -0.0258917 |
| SRP54 | signal recognition particle 54kDa | -0.0253884 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0252005 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0251991 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0251498 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0251228 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0246989 |
| LMO7 | LIM domain 7 | -0.0246312 |
| PARD3 | par-3 family cell polarity regulator | -0.0242545 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0239739 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0237325 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0234697 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.023447 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0233037 |
| MGAT4C | MGAT4 family, member C | -0.0232905 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0232901 |
| ARCN1 | archain 1 | -0.0232782 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0231916 |
| CDCP1 | CUB domain containing protein 1 | -0.0231462 |
| SEC24D | SEC24 family member D | -0.0230212 |
| HMGA1 | high mobility group AT-hook 1 | -0.0217882 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0217463 |
| CAV2 | caveolin 2 | -0.0216716 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0212274 |
| COG5 | component of oligomeric golgi complex 5 | -0.0211137 |
| TAOK1 | TAO kinase 1 | -0.0210411 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0208169 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0206445 |
| SRP72 | signal recognition particle 72kDa | -0.0205626 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0205279 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0204423 |
| FLNB | filamin B, beta | -0.020324 |
| TMF1 | TATA element modulatory factor 1 | -0.0202692 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0201051 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0199851 |
| RPS27A | ribosomal protein S27a | -0.0199658 |
| PERP | PERP, TP53 apoptosis effector | -0.0197803 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0196962 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0196734 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0196277 |
| RSF1 | remodeling and spacing factor 1 | -0.0196273 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0196062 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0195731 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0193232 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0192738 |
| GOLGA4 | golgin A4 | -0.0192648 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0192289 |
