| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Drospirenone perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Drospirenone_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0865002 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0831382 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.078466 |
| FAM20C | family with sequence similarity 20, member C | 0.0728753 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0682905 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0621172 |
| SMAD3 | SMAD family member 3 | 0.0613726 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0585308 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0558874 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0528969 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0503646 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0495684 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.044588 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0432655 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0425856 |
| PFKP | phosphofructokinase, platelet | 0.0415675 |
| VEGFA | vascular endothelial growth factor A | 0.0409634 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0393353 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0387361 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0383936 |
| CEP250 | centrosomal protein 250kDa | 0.0383897 |
| RPL3 | ribosomal protein L3 | 0.0371576 |
| OGA | O-GlcNAcase | 0.0370237 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0353961 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0328014 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.032582 |
| APP | amyloid beta (A4) precursor protein | 0.0324243 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0315693 |
| CTDSP2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 | 0.0312463 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0308814 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0305984 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0299 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0298814 |
| RBM39 | RNA binding motif protein 39 | 0.029832 |
| TGM2 | transglutaminase 2 | 0.029821 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0297522 |
| RUNX2 | runt-related transcription factor 2 | 0.0296124 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0295184 |
| YBX3 | Y box binding protein 3 | 0.0292003 |
| AOPEP | aminopeptidase O (putative) | 0.0290991 |
| NTN4 | netrin 4 | 0.0290406 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0288713 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0285074 |
| KSR1 | kinase suppressor of ras 1 | 0.0283297 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0281911 |
| MLPH | melanophilin | 0.0275876 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0272325 |
| CABIN1 | calcineurin binding protein 1 | 0.0270652 |
| JUN | jun proto-oncogene | 0.0263722 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0263119 |
| CPNE1 | copine I | 0.0263102 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0257273 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0256952 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0251027 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0249513 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0249361 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0248397 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0245638 |
| EZR | ezrin | 0.0245459 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0245228 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0243579 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0241526 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0240095 |
| INTS1 | integrator complex subunit 1 | 0.0238477 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0235423 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.023411 |
| IL1R1 | interleukin 1 receptor, type I | 0.0232963 |
| COPA | coatomer protein complex, subunit alpha | 0.0232761 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0231919 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0230507 |
| NONO | non-POU domain containing, octamer-binding | 0.0227975 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0222645 |
| YBX1 | Y box binding protein 1 | 0.0220595 |
| FAM13A | family with sequence similarity 13, member A | 0.0219614 |
| FOXO3 | forkhead box O3 | 0.021845 |
| HYOU1 | hypoxia up-regulated 1 | 0.0217538 |
| TNNC1 | troponin C type 1 (slow) | 0.0213261 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0212042 |
| GOLGA3 | golgin A3 | 0.0210982 |
| GOLGA2 | golgin A2 | 0.0210701 |
| ADM | adrenomedullin | 0.020772 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0205749 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0204958 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0204156 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0203976 |
| MINK1 | misshapen-like kinase 1 | 0.0200643 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0200483 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0199036 |
| HLA-C | major histocompatibility complex, class I, C | 0.0198253 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0197634 |
| OPTN | optineurin | 0.0196429 |
| HLA-B | major histocompatibility complex, class I, B | 0.0196273 |
| ZNF516 | zinc finger protein 516 | 0.0195831 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0194964 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.0193075 |
| ACTN4 | actinin, alpha 4 | 0.0192687 |
| COL12A1 | collagen, type XII, alpha 1 | 0.0192492 |
| DUSP16 | dual specificity phosphatase 16 | 0.0191928 |
| SDC4 | syndecan 4 | 0.0191299 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0190053 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.303164 |
| VIM | vimentin | -0.188952 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.134966 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.13482 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.113221 |
| CDH13 | cadherin 13 | -0.103045 |
| FN1 | fibronectin 1 | -0.0987366 |
| EFNA5 | ephrin-A5 | -0.097495 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0910013 |
| LOX | lysyl oxidase | -0.0901667 |
| USP34 | ubiquitin specific peptidase 34 | -0.0887924 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0883099 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0741706 |
| CDCP1 | CUB domain containing protein 1 | -0.073672 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0710321 |
| NRG1 | neuregulin 1 | -0.0670627 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.065956 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0645395 |
| STC1 | stanniocalcin 1 | -0.062032 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0609487 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0609132 |
| MTSS1 | metastasis suppressor 1 | -0.0581392 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0579399 |
| HMGA2 | high mobility group AT-hook 2 | -0.0578853 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.057682 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.057478 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0511027 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0485686 |
| CD44 | CD44 molecule (Indian blood group) | -0.0483496 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0473256 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0448678 |
| HMGA1 | high mobility group AT-hook 1 | -0.0447944 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0431558 |
| RPS8 | ribosomal protein S8 | -0.042951 |
| ENO1 | enolase 1, (alpha) | -0.0414845 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0413201 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0407206 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0406645 |
| SYT1 | synaptotagmin I | -0.0403023 |
| MEF2A | myocyte enhancer factor 2A | -0.0401205 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0401107 |
| EHBP1 | EH domain binding protein 1 | -0.0393938 |
| RPS12 | ribosomal protein S12 | -0.0388912 |
| JMJD1C | jumonji domain containing 1C | -0.0380172 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0377942 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0372195 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0372167 |
| RPS2 | ribosomal protein S2 | -0.0371553 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0369789 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0366954 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0358175 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0353685 |
| RPS6 | ribosomal protein S6 | -0.0353348 |
| PKM | pyruvate kinase, muscle | -0.035031 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.034894 |
| RPL37A | ribosomal protein L37a | -0.034249 |
| ASPH | aspartate beta-hydroxylase | -0.033903 |
| NRP1 | neuropilin 1 | -0.0337688 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0337653 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0336263 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.033246 |
| RPLP1 | ribosomal protein, large, P1 | -0.0331396 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0330182 |
| PTK2 | protein tyrosine kinase 2 | -0.0328728 |
| ATF7 | activating transcription factor 7 | -0.0327992 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0327306 |
| POTEF | POTE ankyrin domain family, member F | -0.032711 |
| DTNA | dystrobrevin, alpha | -0.03264 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0325238 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0323311 |
| RAD51B | RAD51 paralog B | -0.0316608 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0310605 |
| DIAPH2 | diaphanous-related formin 2 | -0.0301001 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.02976 |
| MAP4 | microtubule-associated protein 4 | -0.0294746 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0290905 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0289882 |
| IL1B | interleukin 1, beta | -0.028891 |
| NAV3 | neuron navigator 3 | -0.0286701 |
| RPL31 | ribosomal protein L31 | -0.0285257 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.028515 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0283782 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0282874 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0279416 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.027919 |
| OXR1 | oxidation resistance 1 | -0.0277665 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0277346 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0272669 |
| FBN1 | fibrillin 1 | -0.0271748 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0271578 |
| GPHN | gephyrin | -0.0270457 |
| CA12 | carbonic anhydrase XII | -0.0269857 |
| RPS29 | ribosomal protein S29 | -0.0269092 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0269081 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0267936 |
| RPL34 | ribosomal protein L34 | -0.026455 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0264411 |
| NHSL1 | NHS-like 1 | -0.0261698 |
| GOLGA4 | golgin A4 | -0.0260169 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.025978 |
