| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Drospirenone perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Drospirenone_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | 0.0860973 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0639937 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0607959 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0574712 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.053381 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0533701 |
| APP | amyloid beta (A4) precursor protein | 0.0509216 |
| RPL3 | ribosomal protein L3 | 0.0497298 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0490615 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0489918 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0453187 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0432636 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0430815 |
| CMIP | c-Maf inducing protein | 0.0414659 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0412522 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0388193 |
| HLA-B | major histocompatibility complex, class I, B | 0.0374705 |
| CAVIN1 | caveolae associated protein 1 | 0.0356136 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0353812 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0353504 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0347393 |
| PLEC | plectin | 0.0341959 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0341908 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0338135 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0337752 |
| PYGL | phosphorylase, glycogen, liver | 0.0334314 |
| ACTN1 | actinin, alpha 1 | 0.0326094 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0323324 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0297439 |
| YBX3 | Y box binding protein 3 | 0.0297203 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0296024 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0294958 |
| FLNB | filamin B, beta | 0.0294806 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0293875 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0282939 |
| FMNL2 | formin-like 2 | 0.0273741 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0268996 |
| HLA-C | major histocompatibility complex, class I, C | 0.02683 |
| SFTPA2 | surfactant protein A2 | 0.026694 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.026671 |
| HLA-A | major histocompatibility complex, class I, A | 0.0254615 |
| RPL35A | ribosomal protein L35a | 0.0249914 |
| DST | dystonin | 0.0248906 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0246817 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0244445 |
| MT2A | metallothionein 2A | 0.024374 |
| NDRG1 | N-myc downstream regulated 1 | 0.0242668 |
| RPL13A | ribosomal protein L13a | 0.0242034 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0238924 |
| EGFR | epidermal growth factor receptor | 0.0234719 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0233994 |
| CYTH1 | cytohesin 1 | 0.0232544 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0228433 |
| HYOU1 | hypoxia up-regulated 1 | 0.0228316 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0227721 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0227028 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 | 0.0224153 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.022346 |
| CABIN1 | calcineurin binding protein 1 | 0.0222688 |
| RPL41 | ribosomal protein L41 | 0.0222606 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0221096 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0220491 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0220387 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0214473 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0213359 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0212577 |
| BRD2 | bromodomain containing 2 | 0.0210423 |
| CPNE1 | copine I | 0.0207764 |
| CALR | calreticulin | 0.0207529 |
| PTK2 | protein tyrosine kinase 2 | 0.0206981 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0206916 |
| FLNA | filamin A, alpha | 0.0204634 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0203154 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0202172 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0201345 |
| RPL11 | ribosomal protein L11 | 0.0197294 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0194531 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0193715 |
| SPAG5 | sperm associated antigen 5 | 0.0192042 |
| SF1 | splicing factor 1 | 0.0191944 |
| USP36 | ubiquitin specific peptidase 36 | 0.0191301 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0190799 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0189819 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0189722 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0188588 |
| LDHA | lactate dehydrogenase A | 0.0188583 |
| CTBP2 | C-terminal binding protein 2 | 0.0188489 |
| NONO | non-POU domain containing, octamer-binding | 0.0188271 |
| ZFHX3 | zinc finger homeobox 3 | 0.018706 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0186534 |
| PARD3 | par-3 family cell polarity regulator | 0.0186463 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0185622 |
| JUN | jun proto-oncogene | 0.0183523 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0183165 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0179543 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0179213 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0178643 |
| MED15 | mediator complex subunit 15 | 0.0176701 |
| TMSB4X | thymosin beta 4, X-linked | 0.0176634 |
| MORF4L2 | mortality factor 4 like 2 | 0.0176203 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.224804 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.159394 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.113096 |
| VIM | vimentin | -0.0888873 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0844164 |
| TXNRD1 | thioredoxin reductase 1 | -0.0826062 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0809857 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0738683 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0647814 |
| RPS27A | ribosomal protein S27a | -0.0628439 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0612077 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0602526 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0596985 |
| POTEF | POTE ankyrin domain family, member F | -0.0575418 |
| UBC | ubiquitin C | -0.0541225 |
| FGB | fibrinogen beta chain | -0.0437959 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0364657 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0349771 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0347687 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0327446 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0327165 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0322791 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0311169 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0301882 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0300681 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0299348 |
| ENO1 | enolase 1, (alpha) | -0.0296583 |
| JMJD1C | jumonji domain containing 1C | -0.0289953 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0281628 |
| RTN4 | reticulon 4 | -0.0266072 |
| RBM25 | RNA binding motif protein 25 | -0.026462 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0263026 |
| RPS12 | ribosomal protein S12 | -0.025443 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0247174 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0244001 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.023521 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0233575 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0233171 |
| VMP1 | vacuole membrane protein 1 | -0.0229979 |
| ASPH | aspartate beta-hydroxylase | -0.0224801 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.022032 |
| NTN4 | netrin 4 | -0.0212152 |
| RPS2 | ribosomal protein S2 | -0.0209643 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0209021 |
| CENPE | centromere protein E, 312kDa | -0.0207588 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0205261 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0202673 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0200562 |
| OSMR | oncostatin M receptor | -0.0199479 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0195967 |
| RPS23 | ribosomal protein S23 | -0.0192383 |
| HMGB1 | high mobility group box 1 | -0.0189996 |
| IER3 | immediate early response 3 | -0.0189476 |
| RPS5 | ribosomal protein S5 | -0.0187946 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0186659 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0185954 |
| YME1L1 | YME1-like 1 ATPase | -0.0184384 |
| TNPO1 | transportin 1 | -0.0184381 |
| RPS15 | ribosomal protein S15 | -0.0182178 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0180678 |
| CBX3 | chromobox homolog 3 | -0.0180503 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0179874 |
| BMP5 | bone morphogenetic protein 5 | -0.0179126 |
| CENPF | centromere protein F, 350/400kDa | -0.0179058 |
| PFN1 | profilin 1 | -0.0178699 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0175598 |
| MKI67 | marker of proliferation Ki-67 | -0.0175576 |
| SRGN | serglycin | -0.0175119 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0175061 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0174232 |
| DENND4A | DENN/MADD domain containing 4A | -0.0173974 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0173885 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0173335 |
| HMGA1 | high mobility group AT-hook 1 | -0.0172172 |
| KYNU | kynureninase | -0.0170375 |
| KLF6 | Kruppel-like factor 6 | -0.0169506 |
| DEK | DEK proto-oncogene | -0.016617 |
| RFWD3 | ring finger and WD repeat domain 3 | -0.0164186 |
| WWOX | WW domain containing oxidoreductase | -0.0163816 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0162997 |
| TMEM131 | transmembrane protein 131 | -0.0162787 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0160853 |
| PAPOLA | poly(A) polymerase alpha | -0.0160577 |
| PTMA | prothymosin, alpha | -0.0159955 |
| PCBP2 | poly(rC) binding protein 2 | -0.0158864 |
| RPL23A | ribosomal protein L23a | -0.0157941 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.015738 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0157174 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0156906 |
| ZNF207 | zinc finger protein 207 | -0.0156011 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0156006 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0155164 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0155073 |
| NOP58 | NOP58 ribonucleoprotein | -0.0153462 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | -0.0153398 |
| IPO7 | importin 7 | -0.0151592 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0150825 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.01506 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | -0.0150458 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0148969 |
