| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Drospirenone perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Drospirenone_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.18581 |
| DST | dystonin | 0.167111 |
| GDA | guanine deaminase | 0.157575 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.133575 |
| GRAMD1B | GRAM domain containing 1B | 0.125921 |
| PM20D1 | peptidase M20 domain containing 1 | 0.120767 |
| ASPH | aspartate beta-hydroxylase | 0.116323 |
| KYNU | kynureninase | 0.0957051 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0956256 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0929251 |
| TXNRD1 | thioredoxin reductase 1 | 0.0896403 |
| MYOF | myoferlin | 0.089587 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0874757 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.078828 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0774136 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0725616 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0668788 |
| TBXT | T-box transcription factor T | 0.0655945 |
| NRCAM | neuronal cell adhesion molecule | 0.0634605 |
| CENPF | centromere protein F, 350/400kDa | 0.0615604 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0607822 |
| NEK7 | NIMA-related kinase 7 | 0.0603826 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0603314 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0571522 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0563017 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0561411 |
| RPL3 | ribosomal protein L3 | 0.0560891 |
| CD109 | CD109 molecule | 0.0542618 |
| NONO | non-POU domain containing, octamer-binding | 0.052201 |
| CTSC | cathepsin C | 0.0520014 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0499846 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0480883 |
| MSN | moesin | 0.0468807 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0465791 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0461852 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0456892 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0455443 |
| PCBP2 | poly(rC) binding protein 2 | 0.0449202 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0445626 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0444957 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0441398 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0437847 |
| EFNA5 | ephrin-A5 | 0.0431205 |
| MFF | mitochondrial fission factor | 0.0430549 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0421479 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0420937 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0410832 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0409467 |
| MCL1 | myeloid cell leukemia 1 | 0.040577 |
| LAMA1 | laminin, alpha 1 | 0.0399403 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0397976 |
| PTEN | phosphatase and tensin homolog | 0.0394242 |
| FLNB | filamin B, beta | 0.0382674 |
| MKI67 | marker of proliferation Ki-67 | 0.0381646 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0380564 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0365504 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0362049 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0361821 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.036114 |
| TMSB10 | thymosin beta 10 | 0.0350728 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0345573 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0342495 |
| LOC112694756 | uncharaterized LOC112694756 | 0.034205 |
| YBX3 | Y box binding protein 3 | 0.0337716 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0335021 |
| RLIM | ring finger protein, LIM domain interacting | 0.0334883 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0330637 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0324919 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0324165 |
| ENAH | enabled homolog (Drosophila) | 0.031752 |
| POTEF | POTE ankyrin domain family, member F | 0.0297474 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0295406 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0295213 |
| COL5A2 | collagen, type V, alpha 2 | 0.0285987 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0281159 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0276909 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0275052 |
| VCL | vinculin | 0.0272673 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0271871 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0270615 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0269511 |
| RPL23 | ribosomal protein L23 | 0.0267651 |
| RTN4 | reticulon 4 | 0.0265735 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0262426 |
| CUL4A | cullin 4A | 0.0261418 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0257281 |
| CEP72 | centrosomal protein 72kDa | 0.0256885 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0256355 |
| CSRP1 | cysteine and glycine-rich protein 1 | 0.0254687 |
| EPHA4 | EPH receptor A4 | 0.0252539 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0252092 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0251148 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.02471 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0242301 |
| MORF4L2 | mortality factor 4 like 2 | 0.0241431 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0241028 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0240999 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0238615 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0236863 |
| PDE10A | phosphodiesterase 10A | 0.0235982 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.24432 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.21669 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.109585 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0995328 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0954843 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0888409 |
| CDH13 | cadherin 13 | -0.0868259 |
| VIM | vimentin | -0.081629 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0807466 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0637012 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.061806 |
| LSAMP | limbic system-associated membrane protein | -0.0511979 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0494187 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0438737 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0414867 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0407716 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.039773 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.03783 |
| NCKAP5 | NCK-associated protein 5 | -0.0359982 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0358835 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0338257 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0331352 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0331213 |
| PCDH9 | protocadherin 9 | -0.0330867 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0320585 |
| RANBP17 | RAN binding protein 17 | -0.0316066 |
| RPLP1 | ribosomal protein, large, P1 | -0.0312316 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0308448 |
| TENM3 | teneurin transmembrane protein 3 | -0.0307453 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0306125 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0306067 |
| SLC16A6 | solute carrier family 16, member 6 | -0.0303664 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0302172 |
| AUTS2 | autism susceptibility candidate 2 | -0.0300968 |
| CANX | calnexin | -0.0293129 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0291871 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.028976 |
| TENM2 | teneurin transmembrane protein 2 | -0.0278279 |
| STC1 | stanniocalcin 1 | -0.0277995 |
| IER3 | immediate early response 3 | -0.0274699 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0271247 |
| RAD51B | RAD51 paralog B | -0.0269329 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0268003 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0263703 |
| DENND1A | DENN/MADD domain containing 1A | -0.0257024 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0253037 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0253011 |
| RPS8 | ribosomal protein S8 | -0.0252342 |
| MAP7 | microtubule-associated protein 7 | -0.0247616 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0246938 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0246907 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0245163 |
| CUX1 | cut-like homeobox 1 | -0.0240635 |
| RAI14 | retinoic acid induced 14 | -0.0238971 |
| UNC5D | unc-5 homolog D (C. elegans) | -0.0235393 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0234875 |
| RPL31 | ribosomal protein L31 | -0.0228711 |
| CHL1 | cell adhesion molecule L1-like | -0.022774 |
| PRELID2 | PRELI domain containing 2 | -0.0226333 |
| SVIL | supervillin | -0.0224807 |
| SQSTM1 | sequestosome 1 | -0.0220385 |
| HMGA2 | high mobility group AT-hook 2 | -0.0215835 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0214808 |
| RPS27A | ribosomal protein S27a | -0.0212847 |
| NBEAL1 | neurobeachin-like 1 | -0.0212322 |
| RPL26 | ribosomal protein L26 | -0.0212287 |
| RPL38 | ribosomal protein L38 | -0.0208084 |
| FNIP1 | folliculin interacting protein 1 | -0.0207572 |
| PCDH15 | protocadherin-related 15 | -0.0200616 |
| CD44 | CD44 molecule (Indian blood group) | -0.0200284 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0199623 |
| RPS29 | ribosomal protein S29 | -0.0198039 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.019387 |
| CCDC68 | coiled-coil domain containing 68 | -0.0193442 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0192306 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0190872 |
| XYLT1 | xylosyltransferase I | -0.01903 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0189877 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0188432 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.018731 |
| RPS24 | ribosomal protein S24 | -0.0185349 |
| RORA | RAR-related orphan receptor A | -0.0179475 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0179129 |
| AEBP2 | AE binding protein 2 | -0.0176123 |
| RHOB | ras homolog family member B | -0.0175747 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0175213 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0173319 |
| CLMP | CXADR-like membrane protein | -0.0172323 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0169393 |
| DTNA | dystrobrevin, alpha | -0.0168346 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0168256 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0167964 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0164119 |
| CADM2 | cell adhesion molecule 2 | -0.0163425 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.016227 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0160725 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0160122 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0159814 |
| RPS6 | ribosomal protein S6 | -0.0159674 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0159093 |
