| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Drospirenone perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Drospirenone_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.0937167 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.081408 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0780656 |
| NTM | neurotrimin | 0.071192 |
| NONO | non-POU domain containing, octamer-binding | 0.0632509 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0568234 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.055115 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0540178 |
| RPL3 | ribosomal protein L3 | 0.0534463 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0481615 |
| MYO10 | myosin X | 0.0475854 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0450178 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0392349 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.038674 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0367601 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0354667 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.034341 |
| PHIP | pleckstrin homology domain interacting protein | 0.0339336 |
| CALR | calreticulin | 0.033453 |
| DLX2 | distal-less homeobox 2 | 0.033081 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0329966 |
| CPNE1 | copine I | 0.0327779 |
| RHEB | Ras homolog enriched in brain | 0.0324233 |
| GSE1 | Gse1 coiled-coil protein | 0.0314267 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0314112 |
| PDGFC | platelet derived growth factor C | 0.0313815 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0298418 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0296714 |
| USP22 | ubiquitin specific peptidase 22 | 0.0290834 |
| GPC4 | glypican 4 | 0.0285085 |
| PGK1 | phosphoglycerate kinase 1 | 0.028508 |
| YAP1 | Yes-associated protein 1 | 0.0284492 |
| TMSB4X | thymosin beta 4, X-linked | 0.0277686 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0274822 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0271073 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0270376 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0269418 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0265332 |
| YBX1 | Y box binding protein 1 | 0.0264392 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0260355 |
| ITGAV | integrin, alpha V | 0.0258783 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0257748 |
| FOXG1 | forkhead box G1 | 0.0257468 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0256348 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.025241 |
| PLS3 | plastin 3 | 0.0251664 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0250759 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0248652 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0243629 |
| MAP7D1 | MAP7 domain containing 1 | 0.0242563 |
| H1-2 | H1.2 linker histone, cluster member | 0.0241409 |
| FUS | FUS RNA binding protein | 0.0240827 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.023797 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0235926 |
| VEGFA | vascular endothelial growth factor A | 0.0234459 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.023407 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0233711 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0232827 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0230624 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0229723 |
| PUM1 | pumilio RNA-binding family member 1 | 0.022911 |
| PLEC | plectin | 0.022704 |
| RPLP0 | ribosomal protein, large, P0 | 0.0223448 |
| CEP250 | centrosomal protein 250kDa | 0.0223275 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.0222774 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0219243 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0219128 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.021486 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0213148 |
| PARD3 | par-3 family cell polarity regulator | 0.0212625 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0211255 |
| PAIP1 | poly(A) binding protein interacting protein 1 | 0.0209411 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0207932 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0207698 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0206871 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0206785 |
| HDAC9 | histone deacetylase 9 | 0.0205649 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0204973 |
| NCKAP1 | NCK-associated protein 1 | 0.0200991 |
| HYOU1 | hypoxia up-regulated 1 | 0.0200965 |
| LEMD3 | LEM domain containing 3 | 0.0200663 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0198752 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0198648 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0197169 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0196889 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0196675 |
| TCP1 | t-complex 1 | 0.0195498 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0193823 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0193405 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0193114 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.0191831 |
| RLIM | ring finger protein, LIM domain interacting | 0.0191707 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.0191521 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0189248 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0189238 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0188732 |
| SON | SON DNA binding protein | 0.0187078 |
| TIMELESS | timeless circadian clock | 0.0186661 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0185748 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0184527 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.170087 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.153131 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.117079 |
| VIM | vimentin | -0.110578 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.10048 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0969527 |
| GPC3 | glypican 3 | -0.0951567 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0854938 |
| PEG10 | paternally expressed 10 | -0.0854836 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0731388 |
| MAP4 | microtubule-associated protein 4 | -0.072975 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.07033 |
| SYT1 | synaptotagmin I | -0.0670654 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0647826 |
| NOP58 | NOP58 ribonucleoprotein | -0.0638145 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.061472 |
| GNAS | GNAS complex locus | -0.0603514 |
| FBXO11 | F-box protein 11 | -0.0531313 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0525075 |
| THBS1 | thrombospondin 1 | -0.0515538 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0513954 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0505143 |
| MKI67 | marker of proliferation Ki-67 | -0.0497894 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0493255 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.048199 |
| EMP1 | epithelial membrane protein 1 | -0.048183 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0473692 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0471893 |
| JMJD1C | jumonji domain containing 1C | -0.0468363 |
| HMGB1 | high mobility group box 1 | -0.0468183 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0463126 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0452693 |
| SRP54 | signal recognition particle 54kDa | -0.0445742 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0442942 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0441395 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | -0.0427512 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.041816 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0415092 |
| NRG1 | neuregulin 1 | -0.040939 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0405977 |
| SNX6 | sorting nexin 6 | -0.0402837 |
| NEBL | nebulette | -0.0398435 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0392576 |
| TENM2 | teneurin transmembrane protein 2 | -0.0392424 |
| BPTF | bromodomain PHD finger transcription factor | -0.0392353 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0389934 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.038885 |
| CPA6 | carboxypeptidase A6 | -0.0388673 |
| CENPF | centromere protein F, 350/400kDa | -0.0383263 |
| CENPE | centromere protein E, 312kDa | -0.0381366 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.037544 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0375418 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0371086 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0370531 |
| CADM2 | cell adhesion molecule 2 | -0.0369698 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0362226 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0361445 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0358875 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0352589 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0348446 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0347297 |
| LRRC4C | leucine rich repeat containing 4C | -0.0346307 |
| RPS16 | ribosomal protein S16 | -0.0346273 |
| VMP1 | vacuole membrane protein 1 | -0.0345443 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0345213 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0345069 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0343192 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0341405 |
| PSPC1 | paraspeckle component 1 | -0.0335062 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0334571 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0334236 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0333766 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0332142 |
| PCDH7 | protocadherin 7 | -0.0329513 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0329288 |
| FNDC3B | fibronectin type III domain containing 3B | -0.032511 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0315505 |
| MATR3 | matrin 3 | -0.0313427 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0311949 |
| TPX2 | TPX2, microtubule-associated | -0.030763 |
| SGO2 | shugoshin 2 | -0.0305506 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0303645 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0302914 |
| MPG | N-methylpurine-DNA glycosylase | -0.0297046 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0296884 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0296307 |
| AHNAK | AHNAK nucleoprotein | -0.0293574 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.029334 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0293024 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0291648 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | -0.0290573 |
| DIPK1A | divergent protein kinase domain 1A | -0.0289382 |
| ANK2 | ankyrin 2, neuronal | -0.028831 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0288052 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.028796 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0285909 |
| TCF12 | transcription factor 12 | -0.0285878 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0285066 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0283558 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0283322 |
