| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Drospirenone perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Drospirenone_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.17402 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0831583 |
| RPL3 | ribosomal protein L3 | 0.0806731 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0767046 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0682177 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0557921 |
| ANKRD11 | ankyrin repeat domain 11 | 0.048043 |
| NONO | non-POU domain containing, octamer-binding | 0.0470559 |
| DSCAM | Down syndrome cell adhesion molecule | 0.046731 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.039613 |
| PLXNA1 | plexin A1 | 0.0392568 |
| ACTG1 | actin gamma 1 | 0.0387097 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0376808 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0363823 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0362532 |
| EGFR | epidermal growth factor receptor | 0.0356547 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0355499 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0353591 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0349725 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0348778 |
| TRERF1 | transcriptional regulating factor 1 | 0.0339722 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0337498 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0334506 |
| MORF4L2 | mortality factor 4 like 2 | 0.0309965 |
| RBM39 | RNA binding motif protein 39 | 0.0305939 |
| ANK2 | ankyrin 2, neuronal | 0.0301099 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.029577 |
| SESN2 | sestrin 2 | 0.0293947 |
| MINK1 | misshapen-like kinase 1 | 0.0292609 |
| PRDX2 | peroxiredoxin 2 | 0.029139 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0290371 |
| CEP250 | centrosomal protein 250kDa | 0.0289835 |
| NUP58 | nucleoporin 58 | 0.0288738 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0287878 |
| PER1 | period circadian clock 1 | 0.0283634 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0283563 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0282715 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0281244 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0280646 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0280092 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0278269 |
| VEGFA | vascular endothelial growth factor A | 0.027761 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.027748 |
| RNF145 | ring finger protein 145 | 0.027451 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0272138 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0270698 |
| MSI2 | musashi RNA-binding protein 2 | 0.0267758 |
| SON | SON DNA binding protein | 0.026539 |
| SETD5 | SET domain containing 5 | 0.0265122 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0264981 |
| PFN1 | profilin 1 | 0.0263373 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0262313 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0260349 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0258643 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0253798 |
| RPS19 | ribosomal protein S19 | 0.0252768 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0251869 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.025041 |
| TMEM41B | transmembrane protein 41B | 0.0248406 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0247799 |
| CABIN1 | calcineurin binding protein 1 | 0.0244927 |
| PDGFC | platelet derived growth factor C | 0.0244029 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0241456 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0241024 |
| CPNE1 | copine I | 0.0238001 |
| BRD2 | bromodomain containing 2 | 0.0233025 |
| PRELID3B | PRELI domain containing 3B | 0.0229785 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.022819 |
| GOLGA2 | golgin A2 | 0.0226312 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0225426 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0225195 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0223621 |
| CALR | calreticulin | 0.0223322 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0222252 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0219892 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0218927 |
| BRD4 | bromodomain containing 4 | 0.021832 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0217409 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0217166 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0215991 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.021511 |
| RPL35 | ribosomal protein L35 | 0.0214786 |
| YBX1 | Y box binding protein 1 | 0.0213872 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0213227 |
| GOLGA4 | golgin A4 | 0.0212828 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.0211764 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0210674 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0210038 |
| CCNL1 | cyclin L1 | 0.0209718 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.020956 |
| RPL13A | ribosomal protein L13a | 0.0208099 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.020745 |
| RPL35A | ribosomal protein L35a | 0.0206039 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0201858 |
| NCOA3 | nuclear receptor coactivator 3 | 0.020084 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0200756 |
| PYGB | phosphorylase, glycogen; brain | 0.0200243 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0199917 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0199722 |
| MT2A | metallothionein 2A | 0.0197543 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.409268 |
| AHNAK | AHNAK nucleoprotein | -0.182155 |
| BMP10 | bone morphogenetic protein 10 | -0.125282 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.102383 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0980861 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0962519 |
| CCND1 | cyclin D1 | -0.0892406 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0854869 |
| PTMA | prothymosin, alpha | -0.0831933 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0795149 |
| UBC | ubiquitin C | -0.0738457 |
| RPS27A | ribosomal protein S27a | -0.0702384 |
| ENO1 | enolase 1, (alpha) | -0.0696001 |
| RPS8 | ribosomal protein S8 | -0.0663402 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0632221 |
| PKM | pyruvate kinase, muscle | -0.0596311 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0563686 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0548982 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.05406 |
| MKI67 | marker of proliferation Ki-67 | -0.0534122 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0524458 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0523396 |
| DIAPH3 | diaphanous-related formin 3 | -0.0522149 |
| BMP2K | BMP2 inducible kinase | -0.0488205 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0471007 |
| RPS12 | ribosomal protein S12 | -0.0457189 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0442298 |
| VCL | vinculin | -0.0425456 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0394291 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0388101 |
| NAV2 | neuron navigator 2 | -0.0381049 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0365541 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0356288 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0335472 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0335374 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0326356 |
| S100A10 | S100 calcium binding protein A10 | -0.032624 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0323 |
| RPS23 | ribosomal protein S23 | -0.0315388 |
| GNAS | GNAS complex locus | -0.0315264 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.031486 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0310425 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0303694 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.030241 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0299478 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0296479 |
| RPL12 | ribosomal protein L12 | -0.0292807 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0289346 |
| RPS13 | ribosomal protein S13 | -0.0285557 |
| ZNF438 | zinc finger protein 438 | -0.0285131 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0283241 |
| RPL37A | ribosomal protein L37a | -0.0282175 |
| RPS6 | ribosomal protein S6 | -0.0280274 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0277382 |
| CCNI | cyclin I | -0.0277247 |
| RPS15 | ribosomal protein S15 | -0.0272371 |
| RPL26 | ribosomal protein L26 | -0.0272295 |
| MAP4 | microtubule-associated protein 4 | -0.0271056 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0270945 |
| RPLP1 | ribosomal protein, large, P1 | -0.0270294 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0268355 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0267499 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0263495 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0263075 |
| RPS2 | ribosomal protein S2 | -0.0261475 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0258774 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0258543 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.025199 |
| CENPF | centromere protein F, 350/400kDa | -0.0249804 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0249322 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0248421 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.024748 |
| DEK | DEK proto-oncogene | -0.0243647 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.024309 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0239857 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0239103 |
| SP100 | SP100 nuclear antigen | -0.0235618 |
| TUBA1B | tubulin, alpha 1b | -0.0234155 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0233894 |
| RHOA | ras homolog family member A | -0.0233686 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0229275 |
| XPO1 | exportin 1 | -0.0227778 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0225077 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0224517 |
| GPATCH8 | G patch domain containing 8 | -0.0223549 |
| RPL34 | ribosomal protein L34 | -0.0222826 |
| RPL31 | ribosomal protein L31 | -0.0222563 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0222145 |
| RPL5 | ribosomal protein L5 | -0.0221595 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0219637 |
| HJURP | Holliday junction recognition protein | -0.0213096 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0212048 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0211811 |
| POTEF | POTE ankyrin domain family, member F | -0.0209637 |
| PKN2 | protein kinase N2 | -0.0207401 |
| RPL30 | ribosomal protein L30 | -0.0206765 |
| ANKRD12 | ankyrin repeat domain 12 | -0.020587 |
| RPLP2 | ribosomal protein, large, P2 | -0.0202494 |
| RPS24 | ribosomal protein S24 | -0.0201754 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0199781 |
