| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Drospirenone perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Drospirenone_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.355258 |
| COL6A3 | collagen, type VI, alpha 3 | 0.235599 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.190454 |
| VEGFA | vascular endothelial growth factor A | 0.186783 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.130087 |
| NONO | non-POU domain containing, octamer-binding | 0.124299 |
| HLA-B | major histocompatibility complex, class I, B | 0.123873 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.109791 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.10112 |
| MSN | moesin | 0.0921808 |
| SFTPA2 | surfactant protein A2 | 0.0882757 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0855755 |
| HLA-A | major histocompatibility complex, class I, A | 0.0846751 |
| DST | dystonin | 0.0755557 |
| CEP250 | centrosomal protein 250kDa | 0.0641717 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0625461 |
| ADM | adrenomedullin | 0.0614529 |
| MLPH | melanophilin | 0.060311 |
| SMAD3 | SMAD family member 3 | 0.0600102 |
| RPL3 | ribosomal protein L3 | 0.0592623 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0582271 |
| FRMD4A | FERM domain containing 4A | 0.0579965 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0578347 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0573494 |
| LOC112694756 | uncharaterized LOC112694756 | 0.056868 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0552536 |
| TMSB4X | thymosin beta 4, X-linked | 0.0545108 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0533315 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0502987 |
| FLNA | filamin A, alpha | 0.0501953 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0501362 |
| TNS3 | tensin 3 | 0.0481061 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0478441 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0461099 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0447031 |
| OPTN | optineurin | 0.0441286 |
| MYOF | myoferlin | 0.0438063 |
| FTL | ferritin, light polypeptide | 0.0434054 |
| HLA-C | major histocompatibility complex, class I, C | 0.0410056 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.04035 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0402832 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0377204 |
| COL5A1 | collagen, type V, alpha 1 | 0.0372471 |
| ACTG1 | actin gamma 1 | 0.0369633 |
| APP | amyloid beta (A4) precursor protein | 0.0355849 |
| HDAC9 | histone deacetylase 9 | 0.0353804 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.033706 |
| B2M | beta-2-microglobulin | 0.0333508 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0333416 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0332912 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0331197 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0330869 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0330293 |
| ACTN1 | actinin, alpha 1 | 0.0327383 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0320693 |
| YBX1 | Y box binding protein 1 | 0.0318925 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0315489 |
| PCBP2 | poly(rC) binding protein 2 | 0.0313786 |
| CALR | calreticulin | 0.0308101 |
| PFKP | phosphofructokinase, platelet | 0.0306093 |
| RNF213 | ring finger protein 213 | 0.0304348 |
| RPS6 | ribosomal protein S6 | 0.0298252 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0296825 |
| RPL23 | ribosomal protein L23 | 0.0294104 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0292592 |
| FLNB | filamin B, beta | 0.0291443 |
| BRD2 | bromodomain containing 2 | 0.0285886 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0283555 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0283475 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.027728 |
| YBX3 | Y box binding protein 3 | 0.0277261 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0268386 |
| KYNU | kynureninase | 0.0266795 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0265985 |
| CPNE1 | copine I | 0.0265978 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0264771 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0262975 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0262287 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.026041 |
| STC2 | stanniocalcin 2 | 0.0260325 |
| SEPTIN9 | septin 9 | 0.0259436 |
| TMSB10 | thymosin beta 10 | 0.0259252 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0258981 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0257907 |
| PLEC | plectin | 0.0257011 |
| SET | SET nuclear proto-oncogene | 0.0256444 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0253391 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0249331 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0248803 |
| RND3 | Rho family GTPase 3 | 0.024402 |
| FMNL2 | formin-like 2 | 0.0243994 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0241763 |
| RPS4X | ribosomal protein S4, X-linked | 0.0236758 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0236474 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0235632 |
| TGM2 | transglutaminase 2 | 0.0233144 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0231951 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0231732 |
| NDRG1 | N-myc downstream regulated 1 | 0.0231251 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0230612 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.258866 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0722608 |
| CD44 | CD44 molecule (Indian blood group) | -0.0680104 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0667923 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0593983 |
| FN1 | fibronectin 1 | -0.058366 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0574807 |
| IER3 | immediate early response 3 | -0.0570176 |
| VIM | vimentin | -0.0527876 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0493795 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0482216 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.045232 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0436055 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0434505 |
| JMJD1C | jumonji domain containing 1C | -0.0421657 |
| MAP4 | microtubule-associated protein 4 | -0.0402872 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.040081 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0394874 |
| RPS24 | ribosomal protein S24 | -0.0394776 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0394508 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0393542 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0377309 |
| RTN4 | reticulon 4 | -0.0375514 |
| KLF6 | Kruppel-like factor 6 | -0.036367 |
| DEK | DEK proto-oncogene | -0.0353627 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0337358 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0335702 |
| COL1A1 | collagen, type I, alpha 1 | -0.0335352 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0332475 |
| CDCP1 | CUB domain containing protein 1 | -0.0327717 |
| GNAS | GNAS complex locus | -0.032283 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0303445 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0292537 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0292334 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0284648 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0282961 |
| CD2AP | CD2-associated protein | -0.0282409 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0280164 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0279879 |
| TMEM263 | transmembrane protein 263 | -0.0276594 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0267132 |
| SRGN | serglycin | -0.0266 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0265872 |
| CENPF | centromere protein F, 350/400kDa | -0.0265848 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.025668 |
| ANXA2 | annexin A2 | -0.0254122 |
| SP100 | SP100 nuclear antigen | -0.025075 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0248852 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0248852 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0247753 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0244999 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0241219 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0240742 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0233529 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.023033 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0228442 |
| FRMD5 | FERM domain containing 5 | -0.0228147 |
| ARF4 | ADP-ribosylation factor 4 | -0.0226202 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0221789 |
| MKI67 | marker of proliferation Ki-67 | -0.0217287 |
| PTK2 | protein tyrosine kinase 2 | -0.0216865 |
| THBS1 | thrombospondin 1 | -0.0215107 |
| KIF4A | kinesin family member 4A | -0.0210389 |
| NF1 | neurofibromin 1 | -0.0210317 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0207125 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0206507 |
| PRR11 | proline rich 11 | -0.020643 |
| RPS2 | ribosomal protein S2 | -0.0206294 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0203993 |
| SBF2 | SET binding factor 2 | -0.0200575 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0199575 |
| RRBP1 | ribosome binding protein 1 | -0.0198452 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0197206 |
| RPL26 | ribosomal protein L26 | -0.0196846 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0195244 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0195069 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0194779 |
| TXNIP | thioredoxin interacting protein | -0.0192855 |
| ANLN | anillin, actin binding protein | -0.019257 |
| ZNF292 | zinc finger protein 292 | -0.0190261 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0188223 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0187684 |
| RBM39 | RNA binding motif protein 39 | -0.0187344 |
| ENO1 | enolase 1, (alpha) | -0.018649 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0185687 |
| OSMR | oncostatin M receptor | -0.0183348 |
| XAF1 | XIAP associated factor 1 | -0.018332 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | -0.0181953 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0181245 |
| TAPBP | TAP binding protein (tapasin) | -0.0181242 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0181058 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.018037 |
| RPS12 | ribosomal protein S12 | -0.017977 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0178915 |
| CANX | calnexin | -0.0178338 |
| CDC27 | cell division cycle 27 | -0.0177482 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0177357 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0177083 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0176278 |
| PRELID2 | PRELI domain containing 2 | -0.0174307 |
