| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Drospirenone perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Drospirenone_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.111804 |
| CEP250 | centrosomal protein 250kDa | 0.107747 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0944505 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0828478 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.081854 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0757525 |
| YBX3 | Y box binding protein 3 | 0.0721037 |
| CPNE1 | copine I | 0.0683773 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.061397 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0570137 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0549918 |
| NONO | non-POU domain containing, octamer-binding | 0.0526635 |
| SMAD3 | SMAD family member 3 | 0.0522854 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0517811 |
| MSN | moesin | 0.0502305 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0498856 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0498032 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0496191 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0468834 |
| SET | SET nuclear proto-oncogene | 0.0465198 |
| CENPF | centromere protein F, 350/400kDa | 0.0464129 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0454087 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0446981 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0424095 |
| SEPTIN2 | septin 2 | 0.0421287 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0421262 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0416259 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0413515 |
| PRELID2 | PRELI domain containing 2 | 0.0377298 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0376734 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0372553 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0352541 |
| RNF145 | ring finger protein 145 | 0.035032 |
| MKI67 | marker of proliferation Ki-67 | 0.0347862 |
| ACTG1 | actin gamma 1 | 0.0342617 |
| SDC4 | syndecan 4 | 0.03254 |
| PLEC | plectin | 0.0314356 |
| SON | SON DNA binding protein | 0.0311817 |
| HLA-B | major histocompatibility complex, class I, B | 0.031004 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0308802 |
| ERGIC3 | ERGIC and golgi 3 | 0.0308758 |
| RPL3 | ribosomal protein L3 | 0.0308102 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0307555 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0302268 |
| DSCAM | Down syndrome cell adhesion molecule | 0.029641 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0290463 |
| CAPRIN2 | caprin family member 2 | 0.0288793 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0286686 |
| PKM | pyruvate kinase, muscle | 0.0284267 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0283477 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0281841 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0277476 |
| GOLIM4 | golgi integral membrane protein 4 | 0.0276892 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0275519 |
| MINK1 | misshapen-like kinase 1 | 0.027494 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0273816 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0269326 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0266975 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0266724 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0265683 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0262943 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0262253 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0260953 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0259791 |
| YAP1 | Yes-associated protein 1 | 0.0259727 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.025545 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0253517 |
| GOLGA2 | golgin A2 | 0.0252869 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0251216 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.024665 |
| NUP58 | nucleoporin 58 | 0.0246109 |
| SSH1 | slingshot protein phosphatase 1 | 0.0244871 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.024381 |
| APP | amyloid beta (A4) precursor protein | 0.0241732 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0239592 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0239343 |
| USP22 | ubiquitin specific peptidase 22 | 0.0239114 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0237344 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0236588 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0235472 |
| PCBP2 | poly(rC) binding protein 2 | 0.0233846 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0228942 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0228363 |
| CAVIN1 | caveolae associated protein 1 | 0.0227728 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.0227124 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0227001 |
| BSG | basigin (Ok blood group) | 0.0225133 |
| ACTN1 | actinin, alpha 1 | 0.022454 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0221632 |
| STAG3 | stromal antigen 3 | 0.0221572 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0219212 |
| CALR | calreticulin | 0.021745 |
| CTTN | cortactin | 0.0215877 |
| TPM3 | tropomyosin 3 | 0.0215865 |
| SFTPA2 | surfactant protein A2 | 0.0215192 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.0214811 |
| CALU | calumenin | 0.0214015 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0213957 |
| SNX14 | sorting nexin 14 | 0.0213423 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.021128 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.43578 |
| HMGA2 | high mobility group AT-hook 2 | -0.0595769 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0567767 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0564673 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0554785 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0554351 |
| VIM | vimentin | -0.0537581 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0529321 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0467487 |
| INTS6 | integrator complex subunit 6 | -0.0461513 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0451003 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0448313 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0439953 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.043496 |
| ATM | ATM serine/threonine kinase | -0.0403587 |
| FMN1 | formin 1 | -0.0387882 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0386891 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0375231 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0370443 |
| GNAS | GNAS complex locus | -0.0367172 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0363241 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0335985 |
| TCF12 | transcription factor 12 | -0.0328992 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0328563 |
| TMSB10 | thymosin beta 10 | -0.0327944 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0327398 |
| PRSS23 | protease, serine, 23 | -0.0324745 |
| RAI14 | retinoic acid induced 14 | -0.0324409 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0323148 |
| PRKCA | protein kinase C, alpha | -0.0315353 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0315184 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.031517 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0305173 |
| EXOC4 | exocyst complex component 4 | -0.0283283 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0282597 |
| RIGI | RNA sensor RIG-I | -0.0281676 |
| ENO1 | enolase 1, (alpha) | -0.0280828 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.027727 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0271197 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0269145 |
| BBX | bobby sox homolog (Drosophila) | -0.0266772 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0263845 |
| PCNX4 | pecanex 4 | -0.0263715 |
| NALCN | sodium leak channel, non selective | -0.0263347 |
| DENND5B | DENN/MADD domain containing 5B | -0.0262657 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0262539 |
| ETV6 | ets variant 6 | -0.0261883 |
| IER3 | immediate early response 3 | -0.0261409 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0259452 |
| DST | dystonin | -0.0258677 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0258244 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0256464 |
| DEK | DEK proto-oncogene | -0.0254937 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0254823 |
| NAV3 | neuron navigator 3 | -0.025383 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0253089 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0252793 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0252525 |
| HDAC9 | histone deacetylase 9 | -0.0251218 |
| GPC6 | glypican 6 | -0.0250833 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0250491 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0250304 |
| VCL | vinculin | -0.02495 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0248454 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0247593 |
| IGF2 | insulin-like growth factor 2 | -0.0244394 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0244119 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0241686 |
| SBF2 | SET binding factor 2 | -0.0240162 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0240134 |
| BPTF | bromodomain PHD finger transcription factor | -0.0239337 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0238701 |
| GPATCH2L | G patch domain containing 2-like | -0.0238281 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0238129 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0233684 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0229086 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0228422 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0228384 |
| AK1 | adenylate kinase 1 | -0.0226913 |
| CCND1 | cyclin D1 | -0.0225392 |
| WWOX | WW domain containing oxidoreductase | -0.022503 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.022311 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.02229 |
| TBCA | tubulin folding cofactor A | -0.0220964 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0218214 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0217069 |
| MYO9A | myosin IXA | -0.0215811 |
| NKTR | natural killer cell triggering receptor | -0.0215447 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0214943 |
| ATG7 | autophagy related 7 | -0.0212302 |
| NUP153 | nucleoporin 153kDa | -0.0212074 |
| ARL8B | ADP-ribosylation factor-like 8B | -0.0211109 |
| EGR1 | early growth response 1 | -0.021042 |
| PTK2 | protein tyrosine kinase 2 | -0.0209774 |
| HMGB1 | high mobility group box 1 | -0.0208316 |
| NPR2 | natriuretic peptide receptor 2 | -0.0208263 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0208014 |
| FOXO3 | forkhead box O3 | -0.0207361 |
| USP34 | ubiquitin specific peptidase 34 | -0.0206708 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0206532 |
