| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Drospirenone perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Drospirenone_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.130732 |
| VEGFA | vascular endothelial growth factor A | 0.0855874 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0680322 |
| YBX3 | Y box binding protein 3 | 0.0634042 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0622637 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0611882 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0605867 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0586544 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0539455 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0493724 |
| SMAD3 | SMAD family member 3 | 0.0489907 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0474635 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0456773 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0440047 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0439557 |
| SFTPA2 | surfactant protein A2 | 0.0439539 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0422629 |
| FLNA | filamin A, alpha | 0.0412225 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0402906 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0390705 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0385644 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0380196 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0372214 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0371268 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0366857 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0356069 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0355584 |
| AHR | aryl hydrocarbon receptor | 0.0351745 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.034897 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0346345 |
| KSR1 | kinase suppressor of ras 1 | 0.0346009 |
| PLEC | plectin | 0.0345307 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0341103 |
| PELO | pelota homolog (Drosophila) | 0.0336282 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0331163 |
| DST | dystonin | 0.0322579 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0311275 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0308845 |
| YBX1 | Y box binding protein 1 | 0.0308504 |
| RPL3 | ribosomal protein L3 | 0.0304887 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0285807 |
| NONO | non-POU domain containing, octamer-binding | 0.0283886 |
| RNF145 | ring finger protein 145 | 0.0280516 |
| AFDN | afadin, adherens junction formation factor | 0.0274391 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0271633 |
| SEPTIN9 | septin 9 | 0.0264137 |
| PCBP2 | poly(rC) binding protein 2 | 0.0258754 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0251027 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0250778 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0249442 |
| RUNX2 | runt-related transcription factor 2 | 0.0247289 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0247097 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.0246869 |
| COPA | coatomer protein complex, subunit alpha | 0.0246388 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0242825 |
| PER1 | period circadian clock 1 | 0.0241528 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0240532 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0239317 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0239107 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0238932 |
| FOSL2 | FOS-like antigen 2 | 0.0236808 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0236796 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0235458 |
| GOLGA3 | golgin A3 | 0.023491 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0233385 |
| TGM2 | transglutaminase 2 | 0.0231414 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0229196 |
| OGA | O-GlcNAcase | 0.022902 |
| FAT1 | FAT atypical cadherin 1 | 0.0227981 |
| NUP58 | nucleoporin 58 | 0.0227732 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0227007 |
| ETNK1 | ethanolamine kinase 1 | 0.0226389 |
| RLIM | ring finger protein, LIM domain interacting | 0.022636 |
| MSN | moesin | 0.0223913 |
| MEF2D | myocyte enhancer factor 2D | 0.0219497 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0217405 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0215791 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.0214767 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0214197 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0213607 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0212997 |
| INTS1 | integrator complex subunit 1 | 0.021225 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0212129 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0211178 |
| CAB39 | calcium binding protein 39 | 0.0209604 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0208728 |
| HLA-C | major histocompatibility complex, class I, C | 0.0208196 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0208124 |
| ACTN4 | actinin, alpha 4 | 0.0207778 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0207636 |
| CREBRF | CREB3 regulatory factor | 0.0207472 |
| LMNA | lamin A/C | 0.0207281 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.020399 |
| SON | SON DNA binding protein | 0.0203538 |
| MLPH | melanophilin | 0.0201628 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0200947 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.0200046 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0199302 |
| CD109 | CD109 molecule | 0.0198862 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0198454 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.433262 |
| FN1 | fibronectin 1 | -0.176299 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.171676 |
| NRG1 | neuregulin 1 | -0.167363 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.12101 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.120305 |
| HMGA2 | high mobility group AT-hook 2 | -0.116313 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.113381 |
| ITGA1 | integrin, alpha 1 | -0.104507 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0858939 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0774582 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0693296 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0649308 |
| RAI14 | retinoic acid induced 14 | -0.0538049 |
| CANX | calnexin | -0.0528931 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0483732 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0450871 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0436023 |
| S100A10 | S100 calcium binding protein A10 | -0.0426626 |
| PTMA | prothymosin, alpha | -0.0422874 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0412475 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0397558 |
| S100A6 | S100 calcium binding protein A6 | -0.039365 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0393443 |
| IER3 | immediate early response 3 | -0.0382867 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0375651 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0359821 |
| SYT1 | synaptotagmin I | -0.0359647 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0356676 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.034705 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0319285 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.031495 |
| GNAS | GNAS complex locus | -0.031233 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0300253 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0295916 |
| TXNIP | thioredoxin interacting protein | -0.029372 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0293534 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0292735 |
| ENO1 | enolase 1, (alpha) | -0.0288415 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0285149 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0284566 |
| TMEM263 | transmembrane protein 263 | -0.0283641 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0283498 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0277468 |
| MTDH | metadherin | -0.0275323 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0272803 |
| TMEM165 | transmembrane protein 165 | -0.0270643 |
| ACTG1 | actin gamma 1 | -0.0269833 |
| HMGA1 | high mobility group AT-hook 1 | -0.0264381 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0263265 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0258884 |
| TMEM156 | transmembrane protein 156 | -0.0257176 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0253002 |
| VIM | vimentin | -0.0243814 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0242849 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0241166 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0239667 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.023393 |
| MAP1B | microtubule-associated protein 1B | -0.0232312 |
| FTL | ferritin, light polypeptide | -0.0231629 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.023085 |
| KLHL5 | kelch-like family member 5 | -0.0230027 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0227276 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0226631 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0225192 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0224668 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0224175 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0223534 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0220079 |
| EREG | epiregulin | -0.0219709 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0216824 |
| PLIN2 | perilipin 2 | -0.0214153 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0212714 |
| EFNA5 | ephrin-A5 | -0.0212154 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0211412 |
| RPL34 | ribosomal protein L34 | -0.0210984 |
| CCND1 | cyclin D1 | -0.0210592 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0207892 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0205697 |
| RPS8 | ribosomal protein S8 | -0.0204024 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0203637 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0202503 |
| SFRP1 | secreted frizzled-related protein 1 | -0.019841 |
| RPS15 | ribosomal protein S15 | -0.0197816 |
| UBC | ubiquitin C | -0.019771 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0194863 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0192441 |
| CDK13 | cyclin-dependent kinase 13 | -0.0190427 |
| DENND5B | DENN/MADD domain containing 5B | -0.018693 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0186677 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0186207 |
| MAP4 | microtubule-associated protein 4 | -0.0184462 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0183747 |
| RPS29 | ribosomal protein S29 | -0.0179954 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0179345 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0179077 |
| DUSP6 | dual specificity phosphatase 6 | -0.0178461 |
| RTN4 | reticulon 4 | -0.0176727 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0173966 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0173649 |
