Dry Eye Syndromes Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0013238
Similar Terms
Downloads & Tools

Genes

155 genes associated with the disease Dry Eye Syndromes in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ACAT1 acetyl-CoA acetyltransferase 1
ACE angiotensin I converting enzyme
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADIPOQ adiponectin, C1Q and collagen domain containing
AIRE autoimmune regulator
ALB albumin
AQP5 aquaporin 5
AR androgen receptor
ATG5 autophagy related 5
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BHLHA15 basic helix-loop-helix family, member a15
BPIFA2 BPI fold containing family A, member 2
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
CA6 carbonic anhydrase VI
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCL21 chemokine (C-C motif) ligand 21
CCL3 chemokine (C-C motif) ligand 3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR7 chemokine (C-C motif) receptor 7
CD207 CD207 molecule, langerin
CD47 CD47 molecule
CES1 carboxylesterase 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHIA chitinase, acidic
CLU clusterin
CNTN3 contactin 3 (plasmacytoma associated)
CP ceruloplasmin (ferroxidase)
CREBZF CREB/ATF bZIP transcription factor
CRISP2 cysteine-rich secretory protein 2
CRP C-reactive protein, pentraxin-related
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTSS cathepsin S
DEFB4A defensin, beta 4A
DEFB4B defensin, beta 4B
DNASE1 deoxyribonuclease I
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ELOVL1 ELOVL fatty acid elongase 1
ELOVL4 ELOVL fatty acid elongase 4
ESR1 estrogen receptor 1
FAM109A family with sequence similarity 109, member A
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GSTP1 glutathione S-transferase pi 1
HAMP hepcidin antimicrobial peptide
HCFC1 host cell factor C1
HLA-C major histocompatibility complex, class I, C
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HPGDS hematopoietic prostaglandin D synthase
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HTN1 histatin 1
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL13 interleukin 13
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL33 interleukin 33
IL5 interleukin 5
IL6 interleukin 6
INS insulin
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAG1 jagged 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
LCAT lecithin-cholesterol acyltransferase
LEAP2 liver expressed antimicrobial peptide 2
LGALS3 lectin, galactoside-binding, soluble, 3
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MMP9 matrix metallopeptidase 9
MPI mannose phosphate isomerase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC1 mucin 1, cell surface associated
MUC16 mucin 16, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC7 mucin 7, secreted
MYD88 myeloid differentiation primary response 88
MZB1 marginal zone B and B1 cell-specific protein
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NLRP3 NLR family, pyrin domain containing 3
NLRP6 NLR family, pyrin domain containing 6
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NSD2 nuclear receptor binding SET domain protein 2
OSM oncostatin M
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAX6 paired box 6
PLTP phospholipid transfer protein
POMC proopiomelanocortin
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRG4 proteoglycan 4
PRR4 proline rich 4 (lacrimal)
PRSS55 protease, serine, 55
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGN regucalcin
RMDN1 regulator of microtubule dynamics 1
RMDN2 regulator of microtubule dynamics 2
RMDN3 regulator of microtubule dynamics 3
RO60 Ro60, Y RNA binding protein
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
SCRN1 secernin 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SFTPD surfactant protein D
SOAT1 sterol O-acyltransferase 1
SOD1 superoxide dismutase 1, soluble
SPDEF SAM pointed domain containing ETS transcription factor
SPRR1B small proline-rich protein 1B
SPRR2A small proline-rich protein 2A
SPZ1 spermatogenic leucine zipper 1
SQSTM1 sequestosome 1
SSB Sjogren syndrome antigen B (autoantigen La)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SYBU syntabulin (syntaxin-interacting)
TAC1 tachykinin, precursor 1
TBCE tubulin folding cofactor E
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGM1 transglutaminase 1
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR10 toll-like receptor 10
TLR4 toll-like receptor 4
TLR8 toll-like receptor 8
TMSB4X thymosin beta 4, X-linked
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TNF tumor necrosis factor
TRIM21 tripartite motif containing 21
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VAMP8 vesicle-associated membrane protein 8
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor