Dupuytren Contracture Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An abnormality of the hand resulting from contracture of the palmar fascia with a fixed flexion deformity of the metacarpophalangeal (MCP) joints and the proximal interphalangeal (PIP) joints. (Human Phenotype Ontology, HP_0005679)
External Link https://www.disgenet.org/browser/0/1/0/C0013312
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Genes

31 genes associated with the disease Dupuytren Contracture in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACTB actin, beta
ATL1 atlastin GTPase 1
BOP1 block of proliferation 1
CEP295NL CEP295 N-terminal like
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DDR2 discoidin domain receptor tyrosine kinase 2
DES desmin
DUXA double homeobox A
EBF2 early B-cell factor 2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF3E eukaryotic translation initiation factor 3, subunit E
EPDR1 ependymin related 1
FGF2 fibroblast growth factor 2 (basic)
FN1 fibronectin 1
GAPDH glyceraldehyde-3-phosphate dehydrogenase
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
ITGA11 integrin, alpha 11
KIF5A kinesin family member 5A
MMP14 matrix metallopeptidase 14 (membrane-inserted)
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
RAB31 RAB31, member RAS oncogene family
SFRP4 secreted frizzled-related protein 4
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TIMP2 TIMP metallopeptidase inhibitor 2
TP53 tumor protein p53
WNT2 wingless-type MMTV integration site family member 2
ZC3H12D zinc finger CCCH-type containing 12D