Dysgerminoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A germ cell cancer that derives_from cells that give rise to egg cells. (Human Disease Ontology, DOID_4441)
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Genes

126 genes co-occuring with the disease Dysgerminoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
AFP alpha-fetoprotein 2.797
TSPY1 testis specific protein, Y-linked 1 2.794
SALL4 spalt-like transcription factor 4 2.727
SRY sex determining region Y 2.68
ALPP alkaline phosphatase, placental 2.599
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.589
POU5F1 POU class 5 homeobox 1 2.372
FOXL2 forkhead box L2 2.365
DMRT1 doublesex and mab-3 related transcription factor 1 2.218
AMH anti-Mullerian hormone 2.216
WT1 Wilms tumor 1 2.186
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 2.145
CALB2 calbindin 2 2.088
GPC3 glypican 3 2.068
NR0B1 nuclear receptor subfamily 0, group B, member 1 1.995
KITLG KIT ligand 1.978
DHH desert hedgehog 1.947
RNF139 ring finger protein 139 1.942
NR5A1 nuclear receptor subfamily 5, group A, member 1 1.938
SOX9 SRY (sex determining region Y)-box 9 1.89
PTHLH parathyroid hormone-like hormone 1.829
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.826
NANOG Nanog homeobox 1.797
PDPN podoplanin 1.737
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 1.721
KRT7 keratin 7, type II 1.695
WNT4 wingless-type MMTV integration site family, member 4 1.688
ENO2 enolase 2 (gamma, neuronal) 1.664
CD99 CD99 molecule 1.654
SOX2 SRY (sex determining region Y)-box 2 1.651
ZFY zinc finger protein, Y-linked 1.646
BRCA1 breast cancer 1, early onset 1.628
CD99L2 CD99 molecule-like 2 1.596
TP53 tumor protein p53 1.595
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 1.591
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.536
NANOS3 nanos homolog 3 (Drosophila) 1.53
BRCA2 breast cancer 2, early onset 1.504
DICER1 dicer 1, ribonuclease type III 1.504
PRL prolactin 1.497
PRDM14 PR domain containing 14 1.492
LIN28A lin-28 homolog A (C. elegans) 1.488
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.483
YBX2 Y box binding protein 2 1.481
KRAS Kirsten rat sarcoma viral oncogene homolog 1.48
SYP synaptophysin 1.461
PTH parathyroid hormone 1.435
MME membrane metallo-endopeptidase 1.434
LEFTY1 left-right determination factor 1 1.393
INSM1 insulinoma-associated 1 1.392
ARID1A AT rich interactive domain 1A (SWI-like) 1.389
PAX8 paired box 8 1.385
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.379
TSPYL1 TSPY-like 1 1.377
NUTM1 NUT midline carcinoma, family member 1 1.361
TCF4 transcription factor 4 1.361
GATA4 GATA binding protein 4 1.346
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 1.339
SPRY4 sprouty homolog 4 (Drosophila) 1.339
KRT20 keratin 20, type I 1.328
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.317
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 1.314
DAZ4 deleted in azoospermia 4 1.314
PTEN phosphatase and tensin homolog 1.311
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.305
AR androgen receptor 1.298
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.295
DAZ1 deleted in azoospermia 1 1.272
DPPA3 developmental pluripotency associated 3 1.269
ATF7IP activating transcription factor 7 interacting protein 1.261
INSL3 insulin-like 3 (Leydig cell) 1.255
CD34 CD34 molecule 1.249
CBX2 chromobox homolog 2 1.246
ESR1 estrogen receptor 1 1.231
PGR progesterone receptor 1.229
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.229
LEFTY2 left-right determination factor 2 1.219
PTPRC protein tyrosine phosphatase, receptor type, C 1.213
CD274 CD274 molecule 1.202
BAK1 BCL2-antagonist/killer 1 1.2
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.199
PLBD1 phospholipase B domain containing 1 1.197
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.194
GATA6 GATA binding protein 6 1.193
NCAM1 neural cell adhesion molecule 1 1.19
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 1.186
POMC proopiomelanocortin 1.176
PAGE1 P antigen family, member 1 (prostate associated) 1.171
CSH2 chorionic somatomammotropin hormone 2 1.162
UTF1 undifferentiated embryonic cell transcription factor 1 1.161
TATDN1 TatD DNase domain containing 1 1.154
CDX2 caudal type homeobox 2 1.15
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.143
ZNF708 zinc finger protein 708 1.143
TCL1A T-cell leukemia/lymphoma 1A 1.141
RSPO1 R-spondin 1 1.138
DAZL deleted in azoospermia-like 1.126
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 1.125
LNPEP leucyl/cystinyl aminopeptidase 1.117
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 1.115
DAZ2 deleted in azoospermia 2 1.114
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.114
SSX2 synovial sarcoma, X breakpoint 2 1.107
SSX2B synovial sarcoma, X breakpoint 2B 1.103
GFAP glial fibrillary acidic protein 1.102
ZFPM2 zinc finger protein, FOG family member 2 1.095
TCL1B T-cell leukemia/lymphoma 1B 1.088
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.087
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 1.087
GDF9 growth differentiation factor 9 1.086
PROP1 PROP paired-like homeobox 1 1.085
POM121 POM121 transmembrane nucleoporin 1.071
ERBB2 erb-b2 receptor tyrosine kinase 2 1.069
ADAP1 ArfGAP with dual PH domains 1 1.069
DMRT2 doublesex and mab-3 related transcription factor 2 1.067
PROM1 prominin 1 1.054
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.045
NF1 neurofibromin 1 1.042
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 1.039
PRDM1 PR domain containing 1, with ZNF domain 1.027
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.024
TGFB1 transforming growth factor, beta 1 1.015
FIGLA folliculogenesis specific basic helix-loop-helix 1.015
DEFB129 defensin, beta 129 1.006
EPCAM epithelial cell adhesion molecule 1.005
TUBGCP2 tubulin, gamma complex associated protein 2 1.002