Dystonia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D004421
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Genes

220 genes/proteins associated with the disease Dystonia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 2.88009
TOR1A torsin family 1, member A (torsin A) 2.88009
TH tyrosine hydroxylase 2.88009
THAP1 THAP domain containing, apoptosis associated protein 1 2.88009
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.88009
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 2.88009
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 2.88009
ACTB actin, beta 2.88009
SERAC1 serine active site containing 1 2.88009
SCP2 sterol carrier protein 2 2.88009
GCH1 GTP cyclohydrolase 1 2.88009
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 2.88009
CIZ1 CDKN1A interacting zinc finger protein 1 2.88009
DRD2 dopamine receptor D2 2.52114
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.47951
PRL prolactin 2.43312
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.4218
DRD1 dopamine receptor D1 2.41374
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.40342
BDNF brain-derived neurotrophic factor 2.3285
FOS FBJ murine osteosarcoma viral oncogene homolog 2.30109
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 2.23502
CAT catalase 2.13238
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.082
SOD1 superoxide dismutase 1, soluble 2.0644
MAPK1 mitogen-activated protein kinase 1 2.03368
MAPK3 mitogen-activated protein kinase 3 2.00996
DRD3 dopamine receptor D3 2.00343
EGR1 early growth response 1 2.00165
PENK proenkephalin 1.99567
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.99351
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.9912
CRH corticotropin releasing hormone 1.972
TNF tumor necrosis factor 1.96774
NUPR1 nuclear protein, transcriptional regulator, 1 1.94311
BAX BCL2-associated X protein 1.94046
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.92265
NPY neuropeptide Y 1.89504
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.89488
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.88159
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.87875
BCL2 B-cell CLL/lymphoma 2 1.87194
CALCA calcitonin-related polypeptide alpha 1.86271
APP amyloid beta (A4) precursor protein 1.8608
JUN jun proto-oncogene 1.86062
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.84675
CREB1 cAMP responsive element binding protein 1 1.84605
NOS2 nitric oxide synthase 2, inducible 1.80887
MAOB monoamine oxidase B 1.79981
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.79904
TAC1 tachykinin, precursor 1 1.78987
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.78759
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.78587
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.77335
OPRM1 opioid receptor, mu 1 1.755
ARC activity-regulated cytoskeleton-associated protein 1.71111
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.69426
CES2 carboxylesterase 2 1.66382
ACHE acetylcholinesterase (Yt blood group) 1.65842
MAPK8 mitogen-activated protein kinase 8 1.64573
POMC proopiomelanocortin 1.64371
HRH1 histamine receptor H1 1.62893
GSK3B glycogen synthase kinase 3 beta 1.62669
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.60244
IL6 interleukin 6 1.59497
MAOA monoamine oxidase A 1.59125
DUSP1 dual specificity phosphatase 1 1.58889
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.58584
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.58561
CNR1 cannabinoid receptor 1 (brain) 1.58444
INS insulin 1.57806
NGF nerve growth factor (beta polypeptide) 1.56337
RGS2 regulator of G-protein signaling 2 1.56117
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.55206
JUNB jun B proto-oncogene 1.55182
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.54986
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 1.54645
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 1.54523
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.5311
BCHE butyrylcholinesterase 1.5284
GFAP glial fibrillary acidic protein 1.5254
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.5065
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.50574
INHBE inhibin, beta E 1.49864
HOMER1 homer scaffolding protein 1 1.49304
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.49174
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.48454
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.4753
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.45564
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.45299
CCND1 cyclin D1 1.44845
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.44409
SOD2 superoxide dismutase 2, mitochondrial 1.44084
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 1.43212
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.43076
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.42183
TAGLN transgelin 1.41586
C10ORF10 chromosome 10 open reading frame 10 1.41451
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.41451
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.40953
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.40008
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.39451
VEGFA vascular endothelial growth factor A 1.38863
PDYN prodynorphin 1.38469
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.37761
FAS Fas cell surface death receptor 1.37303
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.37132
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.35184
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.35155
SREBF1 sterol regulatory element binding transcription factor 1 1.35127
FNDC4 fibronectin type III domain containing 4 1.34664
CDK5 cyclin-dependent kinase 5 1.34606
FABP1 fatty acid binding protein 1, liver 1.34547
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.34401
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.34053
GRIK2 glutamate receptor, ionotropic, kainate 2 1.3311
TP53 tumor protein p53 1.32221
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.30758
GSTP1 glutathione S-transferase pi 1 1.30117
CES1 carboxylesterase 1 1.29966
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.29843
GDNF glial cell derived neurotrophic factor 1.29103
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.29011
GJA1 gap junction protein, alpha 1, 43kDa 1.27255
FGF2 fibroblast growth factor 2 (basic) 1.267
RELN reelin 1.26267
IFNG interferon, gamma 1.25525
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.24528
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.24401
IL1B interleukin 1, beta 1.2437
CREM cAMP responsive element modulator 1.23775
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.23712
BCL2L1 BCL2-like 1 1.23712
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.22566
COMT catechol-O-methyltransferase 1.22274
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.22274
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.21599
RGS4 regulator of G-protein signaling 4 1.20978
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.20978
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.2046
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.19477
NTS neurotensin 1.19477
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.19246
NGFR nerve growth factor receptor 1.1908
AVP arginine vasopressin 1.18751
GRM1 glutamate receptor, metabotropic 1 1.1862
HMOX1 heme oxygenase 1 1.18489
RGS9 regulator of G-protein signaling 9 1.18293
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.18126
TUBA4A tubulin, alpha 4a 1.18126
EFNA2 ephrin-A2 1.18026
MPO myeloperoxidase 1.18026
ATF3 activating transcription factor 3 1.17959
FOSL2 FOS-like antigen 2 1.17662
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 1.17596
SNAP25 synaptosomal-associated protein, 25kDa 1.17202
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.16833
DDIT3 DNA-damage-inducible transcript 3 1.16733
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.15022
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.14885
PLP1 proteolipid protein 1 1.14885
EGFR epidermal growth factor receptor 1.14575
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.13997
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.13586
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.13177
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.13041
SREBF2 sterol regulatory element binding transcription factor 2 1.12737
GH1 growth hormone 1 1.12737
CXCL8 chemokine (C-X-C motif) ligand 8 1.12703
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 1.12426
SC5D sterol-C5-desaturase 1.12323
CXCL2 chemokine (C-X-C motif) ligand 2 1.12185
ADORA2A adenosine A2a receptor 1.12082
TRH thyrotropin-releasing hormone 1.11501
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 1.11255
OPRD1 opioid receptor, delta 1 1.10317
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.10282
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.10104
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.09963
MAP2K1 mitogen-activated protein kinase kinase 1 1.09892
GADD45A growth arrest and DNA-damage-inducible, alpha 1.09716
PER1 period circadian clock 1 1.09506
EFNB3 ephrin-B3 1.09226
GSK3A glycogen synthase kinase 3 alpha 1.09011
PRLR prolactin receptor 1.08797
HPN hepsin 1.08478
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.08407
MAPK14 mitogen-activated protein kinase 14 1.08161
CTSL cathepsin L 1.07947
INHA inhibin, alpha 1.07947
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.07696
ELK1 ELK1, member of ETS oncogene family 1.07625
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.07411
ANXA4 annexin A4 1.07269
EGR2 early growth response 2 1.06881
PARP1 poly (ADP-ribose) polymerase 1 1.06844
PVALB parvalbumin 1.05936
IL10 interleukin 10 1.059
JUND jun D proto-oncogene 1.05793
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 1.05461
GRIK5 glutamate receptor, ionotropic, kainate 5 1.05274
GSTM1 glutathione S-transferase mu 1 1.05237
STAR steroidogenic acute regulatory protein 1.04501
DRD4 dopamine receptor D4 1.04465
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.04427
PRKCD protein kinase C, delta 1.04201
MAP1B microtubule-associated protein 1B 1.03976
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.03789
CCKBR cholecystokinin B receptor 1.0353
NCAN neurocan 1.03159
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.03122
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 1.03046
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.02858
GAP43 growth associated protein 43 1.02746
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled 1.0241
LHB luteinizing hormone beta polypeptide 1.02299
TGFA transforming growth factor, alpha 1.02151
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 1.02151
GRM5 glutamate receptor, metabotropic 5 1.02151
DUSP6 dual specificity phosphatase 6 1.0189