Dysuria Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Painful or difficult urination. (Human Phenotype Ontology, HP_0100518)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D053159
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Genes

326 genes/proteins associated with the disease Dysuria from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.55206
GFRA1 GDNF family receptor alpha 1 1.53603
H2AFX H2A histone family, member X 1.50852
VCAM1 vascular cell adhesion molecule 1 1.50273
BUB3 BUB3 mitotic checkpoint protein 1.5012
GAMT guanidinoacetate N-methyltransferase 1.50095
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.49635
MCL1 myeloid cell leukemia 1 1.49508
THBS1 thrombospondin 1 1.48505
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.48145
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.47012
PRC1 protein regulator of cytokinesis 1 1.46515
ERBB2 erb-b2 receptor tyrosine kinase 2 1.44544
MGMT O-6-methylguanine-DNA methyltransferase 1.44139
UNG uracil-DNA glycosylase 1.41174
E2F3 E2F transcription factor 3 1.4026
G0S2 G0/G1 switch 2 1.39952
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.3793
TAGLN transgelin 1.37817
CTSL cathepsin L 1.37446
CCL2 chemokine (C-C motif) ligand 2 1.37132
MELK maternal embryonic leucine zipper kinase 1.36735
CXCL8 chemokine (C-X-C motif) ligand 8 1.36677
BTG3 BTG family, member 3 1.3639
PRNP prion protein 1.3639
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.3639
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.36247
TUBB tubulin, beta class I 1.35763
EGR1 early growth response 1 1.35676
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.35618
FAS Fas cell surface death receptor 1.35531
KIAA1467 KIAA1467 1.35502
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.35271
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.35012
HLA-G major histocompatibility complex, class I, G 1.34635
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.34547
S100P S100 calcium binding protein P 1.34547
GEM GTP binding protein overexpressed in skeletal muscle 1.34547
EPO erythropoietin 1.34343
TGFB1 transforming growth factor, beta 1 1.34343
RFC3 replication factor C (activator 1) 3, 38kDa 1.33672
RRM2 ribonucleotide reductase M2 1.32756
IL6 interleukin 6 1.32251
TP53 tumor protein p53 1.32074
NOS3 nitric oxide synthase 3 (endothelial cell) 1.31927
CDK2 cyclin-dependent kinase 2 1.31867
IL1RN interleukin 1 receptor antagonist 1.31837
BRCA1 breast cancer 1, early onset 1.31686
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.31208
LBP lipopolysaccharide binding protein 1.30941
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.30758
TYMP thymidine phosphorylase 1.30696
F3 coagulation factor III (thromboplastin, tissue factor) 1.30512
PARP1 poly (ADP-ribose) polymerase 1 1.30329
HMMR hyaluronan-mediated motility receptor (RHAMM) 1.29905
CHEK1 checkpoint kinase 1 1.29781
THNSL2 threonine synthase-like 2 (S. cerevisiae) 1.2941
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.29164
SRI sorcin 1.28889
ZNF552 zinc finger protein 552 1.28641
MMP3 matrix metallopeptidase 3 1.28549
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.28456
KIF3A kinesin family member 3A 1.28425
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.28241
IGFBP4 insulin-like growth factor binding protein 4 1.2821
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.27875
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.27751
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.27193
BIRC5 baculoviral IAP repeat containing 5 1.27193
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.26978
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 1.26978
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.26794
GSTP1 glutathione S-transferase pi 1 1.26794
TNF tumor necrosis factor 1.26732
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.26236
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.25369
CDC25B cell division cycle 25B 1.25183
GSTT1 glutathione S-transferase theta 1 1.24905
CD151 CD151 molecule (Raph blood group) 1.24843
RB1 retinoblastoma 1 1.24433
PKP2 plakophilin 2 1.24433
BECN1 beclin 1, autophagy related 1.2437
IL1B interleukin 1, beta 1.24275
HSPA8 heat shock 70kDa protein 8 1.24087
CTGF connective tissue growth factor 1.23962
GSTM1 glutathione S-transferase mu 1 1.23837
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.23616
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.23584
NRP1 neuropilin 1 1.23392
DLC1 DLC1 Rho GTPase activating protein 1.23265
MCM6 minichromosome maintenance complex component 6 1.23201
AURKA aurora kinase A 1.23011
CA12 carbonic anhydrase XII 1.22884
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.22884
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.22884
BIN1 bridging integrator 1 1.22853
NQO1 NAD(P)H dehydrogenase, quinone 1 1.22599
PPARG peroxisome proliferator-activated receptor gamma 1.22566
PPIB peptidylprolyl isomerase B (cyclophilin B) 1.22501
INHBA inhibin, beta A 1.22469
MAPK3 mitogen-activated protein kinase 3 1.22339
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.21631
BMP4 bone morphogenetic protein 4 1.21534
MAPK1 mitogen-activated protein kinase 1 1.21501
COL4A2 collagen, type IV, alpha 2 1.21402
ODC1 ornithine decarboxylase 1 1.21206
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.21043
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.21043
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.21011
UPK3A uroplakin 3A 1.20946
CD8A CD8a molecule 1.20394
HMOX1 heme oxygenase 1 1.20361
BDH1 3-hydroxybutyrate dehydrogenase, type 1 1.20361
NKAIN1 Na+/K+ transporting ATPase interacting 1 1.20064
DDIT3 DNA-damage-inducible transcript 3 1.20031
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.20031
PHYH phytanoyl-CoA 2-hydroxylase 1.19999
POR P450 (cytochrome) oxidoreductase 1.19868
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 1.19704
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.19312
SCUBE2 signal peptide, CUB domain, EGF-like 2 1.19213
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.19146
BAX BCL2-associated X protein 1.19113
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 1.19047
PLSCR1 phospholipid scramblase 1 1.19047
STMN1 stathmin 1 1.18981
EGFR epidermal growth factor receptor 1.18751
ACKR3 atypical chemokine receptor 3 1.18718
APAF1 apoptotic peptidase activating factor 1 1.18652
BBC3 BCL2 binding component 3 1.18489
SOD2 superoxide dismutase 2, mitochondrial 1.18456
TOB1 transducer of ERBB2, 1 1.18424
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.18359
LMCD1 LIM and cysteine-rich domains 1 1.18126
PROCR protein C receptor, endothelial 1.18093
TXNRD1 thioredoxin reductase 1 1.17893
TERT telomerase reverse transcriptase 1.1786
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.17399
CFLAR CASP8 and FADD-like apoptosis regulator 1.17235
MLH1 mutL homolog 1 1.17202
IRS1 insulin receptor substrate 1 1.17101
C1QA complement component 1, q subcomponent, A chain 1.16933
PSAP prosaposin 1.169
CCND3 cyclin D3 1.16799
TFPI2 tissue factor pathway inhibitor 2 1.16633
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.165
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.16335
INSIG1 insulin induced gene 1 1.16203
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.16137
IL15RA interleukin 15 receptor, alpha 1.16137
ALAS2 5'-aminolevulinate synthase 2 1.16104
TGFB2 transforming growth factor, beta 2 1.16035
HSPA1B heat shock 70kDa protein 1B 1.16035
IFNG interferon, gamma 1.15865
SLPI secretory leukocyte peptidase inhibitor 1.15797
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.15763
S100A11 S100 calcium binding protein A11 1.15492
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.15425
ATF5 activating transcription factor 5 1.15256
NFIB nuclear factor I/B 1.15256
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.14816
MOK MOK protein kinase 1.14781
FHL2 four and a half LIM domains 2 1.14713
ITGB4 integrin, beta 4 1.14713
BCL2 B-cell CLL/lymphoma 2 1.14644
AKR1C2 aldo-keto reductase family 1, member C2 1.1461
E2F1 E2F transcription factor 1 1.1461
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.14575
LAMC2 laminin, gamma 2 1.14507
BCL2L1 BCL2-like 1 1.14507
TRIB3 tribbles pseudokinase 3 1.14473
LCN2 lipocalin 2 1.14336
CTSB cathepsin B 1.14336
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 1.14234
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.14234
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.14132
CANX calnexin 1.13929
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.13929
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.13689
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.13689
C3 complement component 3 1.13655
CAV1 caveolin 1, caveolae protein, 22kDa 1.13655
CD44 CD44 molecule (Indian blood group) 1.13381
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.13313
ISG15 ISG15 ubiquitin-like modifier 1.13177
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 1.1294
BIRC6 baculoviral IAP repeat containing 6 1.12357
GADD45A growth arrest and DNA-damage-inducible, alpha 1.12323
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.12082
NFE2L2 nuclear factor, erythroid 2-like 2 1.11877
METRN meteorin, glial cell differentiation regulator 1.11877
LMNB1 lamin B1 1.11741
FADS1 fatty acid desaturase 1 1.11536
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.11501
F2 coagulation factor II (thrombin) 1.11466
FYN FYN proto-oncogene, Src family tyrosine kinase 1.1129
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.1129
TYMS thymidylate synthetase 1.1122
TAT tyrosine aminotransferase 1.11081
CAPN2 calpain 2, (m/II) large subunit 1.11081
CD68 CD68 molecule 1.10838
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.10838
MT2A metallothionein 2A 1.10631
CDC25A cell division cycle 25A 1.10596
IGFBP3 insulin-like growth factor binding protein 3 1.10596
GDNF glial cell derived neurotrophic factor 1.10493
BBS4 Bardet-Biedl syndrome 4 1.10282
FMOD fibromodulin 1.10246
BIRC3 baculoviral IAP repeat containing 3 1.10246
LDLR low density lipoprotein receptor 1.10033
SAT1 spermidine/spermine N1-acetyltransferase 1 1.09927
HADH hydroxyacyl-CoA dehydrogenase 1.09751
CSF1 colony stimulating factor 1 (macrophage) 1.09506
MSH2 mutS homolog 2 1.09332
KDM4B lysine (K)-specific demethylase 4B 1.09332
CIDEB cell death-inducing DFFA-like effector b 1.09226
PCNA proliferating cell nuclear antigen 1.09119
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.09083
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.09047
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.08833
CTNND2 catenin (cadherin-associated protein), delta 2 1.08833
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.0869
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.0869
DRAM1 DNA-damage regulated autophagy modulator 1 1.08266
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.08091
CCNG2 cyclin G2 1.08091
CDKN3 cyclin-dependent kinase inhibitor 3 1.08091
PLK1 polo-like kinase 1 1.08091
TNC tenascin C 1.08091
IL18 interleukin 18 1.07947
TOP2A topoisomerase (DNA) II alpha 170kDa 1.07947
BAD BCL2-associated agonist of cell death 1.0784
G6PD glucose-6-phosphate dehydrogenase 1.0784
CAT catalase 1.07804
DIABLO diablo, IAP-binding mitochondrial protein 1.07696
S100A4 S100 calcium binding protein A4 1.07482
STAT1 signal transducer and activator of transcription 1, 91kDa 1.07411
HDAC1 histone deacetylase 1 1.07269
NPPA natriuretic peptide A 1.07199
NOS2 nitric oxide synthase 2, inducible 1.06987
TJP3 tight junction protein 3 1.06987
FASLG Fas ligand (TNF superfamily, member 6) 1.06987
PLIN2 perilipin 2 1.06917
ERCC1 excision repair cross-complementation group 1 1.06917
ALDOA aldolase A, fructose-bisphosphate 1.06734
MPO myeloperoxidase 1.06734
MAPK7 mitogen-activated protein kinase 7 1.06515
DEK DEK proto-oncogene 1.06515
VEGFA vascular endothelial growth factor A 1.0637
CSTA cystatin A (stefin A) 1.06116
HMGN3 high mobility group nucleosomal binding domain 3 1.0608
LMNA lamin A/C 1.05972
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.05936
CCND1 cyclin D1 1.059
FNDC3B fibronectin type III domain containing 3B 1.05685
XAF1 XIAP associated factor 1 1.05685
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 1.05648
HSPE1 heat shock 10kDa protein 1 1.05573
CXCR6 chemokine (C-X-C motif) receptor 6 1.05461
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 1.05274
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.04904
FLT1 fms-related tyrosine kinase 1 1.04868
CYLD cylindromatosis (turban tumor syndrome) 1.04868
HSPB1 heat shock 27kDa protein 1 1.04794
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.04757
FKBP5 FK506 binding protein 5 1.04684
IL4 interleukin 4 1.04611
MMP2 matrix metallopeptidase 2 1.04611
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.04538
CSE1L CSE1 chromosome segregation 1-like (yeast) 1.04538
DTYMK deoxythymidylate kinase (thymidylate kinase) 1.04465
LHB luteinizing hormone beta polypeptide 1.04427
CXCL10 chemokine (C-X-C motif) ligand 10 1.04389
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.04163
HACL1 2-hydroxyacyl-CoA lyase 1 1.04126
VAV3 vav 3 guanine nucleotide exchange factor 1.04051
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.04014
CCNE1 cyclin E1 1.04014
MUCL1 mucin-like 1 1.03976
EGR2 early growth response 2 1.03827
CREG1 cellular repressor of E1A-stimulated genes 1 1.03827
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 1.03752
NBL1 neuroblastoma 1, DAN family BMP antagonist 1.03752
BID BH3 interacting domain death agonist 1.03715
IGFBP5 insulin-like growth factor binding protein 5 1.03641
MAPK9 mitogen-activated protein kinase 9 1.03493
PERP PERP, TP53 apoptosis effector 1.03419
HDAC4 histone deacetylase 4 1.03382
TNS3 tensin 3 1.03345
FNBP1 formin binding protein 1 1.03308
MAPK8 mitogen-activated protein kinase 8 1.03271
CES2 carboxylesterase 2 1.03197
PRL prolactin 1.03122
UPK1A uroplakin 1A 1.03046
SOAT1 sterol O-acyltransferase 1 1.03046
HCP5 HLA complex P5 (non-protein coding) 1.02708
TRIM68 tripartite motif containing 68 1.02708
GCLM glutamate-cysteine ligase, modifier subunit 1.02671
CLDN7 claudin 7 1.02596
FANCI Fanconi anemia, complementation group I 1.02596
CALR calreticulin 1.02485
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.02485
ERBB4 erb-b2 receptor tyrosine kinase 4 1.02336
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1.02299
RGS2 regulator of G-protein signaling 2 1.02151
LDHA lactate dehydrogenase A 1.02151
CDC25C cell division cycle 25C 1.02003
IL12B interleukin 12B 1.02003
FN1 fibronectin 1 1.01928
RGS1 regulator of G-protein signaling 1 1.01928
QSOX1 quiescin Q6 sulfhydryl oxidase 1 1.01928
ATF3 activating transcription factor 3 1.01928
RAD51 RAD51 recombinase 1.0189
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.0189
MAPK14 mitogen-activated protein kinase 14 1.01852
PRKCB protein kinase C, beta 1.01852
DLAT dihydrolipoamide S-acetyltransferase 1.01625
BCAR3 breast cancer anti-estrogen resistance 3 1.01587
CDC20 cell division cycle 20 1.01512
RPS27L ribosomal protein S27-like 1.01324
TRIM2 tripartite motif containing 2 1.01286
EMP3 epithelial membrane protein 3 1.01286
SRGN serglycin 1.01249
ADM adrenomedullin 1.01212
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.01212
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.01099