E-7449 Gene Set
Genes
13 genes differentially expressed following the E-7449 small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
5.79411
|
|
STK10
|
serine/threonine kinase 10
|
3.43292
|
|
RALGPS2
|
Ral GEF with PH domain and SH3 binding motif 2
|
3.19921
|
|
ADH1C
|
alcohol dehydrogenase 1C (class I), gamma polypeptide
|
3.13248
|
|
NUDT6
|
nudix (nucleoside diphosphate linked moiety X)-type motif 6
|
3.05006
|
|
UGT2B15
|
UDP glucuronosyltransferase 2 family, polypeptide B15
|
3.00224
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
-5.27308
|
|
E2F2
|
E2F transcription factor 2
|
-5.21862
|
|
KIF17
|
kinesin family member 17
|
-3.45456
|
|
RUFY1
|
RUN and FYVE domain containing 1
|
-3.14718
|
|
DNAJC2
|
DnaJ (Hsp40) homolog, subfamily C, member 2
|
-3.10448
|
|
ULK4
|
unc-51 like kinase 4
|
-3.0677
|
|
DKC1
|
dyskeratosis congenita 1, dyskerin
|
-3.00264
|
