| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | E2F transcription factor 1|The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1869) |
| External Link | https://ncbi.nlm.nih.gov/gene/1869 |
| Similar Terms | |
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471 genes differentially expressed following the E2F1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DEFB1 | defensin, beta 1 | 0.018918 |
| PLK1 | polo-like kinase 1 | 0.0151843 |
| LYZ | lysozyme | 0.0146029 |
| CA2 | carbonic anhydrase II | 0.0145981 |
| MGLL | monoglyceride lipase | 0.0134472 |
| TFF1 | trefoil factor 1 | 0.0131819 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0130995 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0129718 |
| RGCC | regulator of cell cycle | 0.0126887 |
| AGR2 | anterior gradient 2 | 0.0126143 |
| PIP | prolactin-induced protein | 0.0125072 |
| CES1 | carboxylesterase 1 | 0.0123885 |
| APOD | apolipoprotein D | 0.0119934 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.0119296 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.0116236 |
| MGP | matrix Gla protein | 0.0113849 |
| FOLR1 | folate receptor 1 (adult) | 0.0111541 |
| TXNDC9 | thioredoxin domain containing 9 | 0.0110685 |
| PCNA | proliferating cell nuclear antigen | 0.0107512 |
| BST2 | bone marrow stromal cell antigen 2 | 0.0107428 |
| S100A9 | S100 calcium binding protein A9 | 0.0107084 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.0106993 |
| MAOA | monoamine oxidase A | 0.0106886 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0106007 |
| ANXA3 | annexin A3 | 0.0104023 |
| CFI | complement factor I | 0.0103608 |
| RND3 | Rho family GTPase 3 | 0.0102403 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.0102042 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0101811 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0101748 |
| CFD | complement factor D (adipsin) | 0.0101134 |
| CRYAB | crystallin, alpha B | 0.0100097 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00993964 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.00993348 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00975976 |
| VSNL1 | visinin-like 1 | 0.00975593 |
| PEG10 | paternally expressed 10 | 0.00972643 |
| GPX2 | glutathione peroxidase 2 | 0.00972445 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00964723 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00961556 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00942919 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00935161 |
| SPON2 | spondin 2, extracellular matrix protein | 0.0093489 |
| TLR4 | toll-like receptor 4 | 0.00926912 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0092575 |
| KLK10 | kallikrein-related peptidase 10 | 0.00921471 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 0.0091269 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00912002 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.0091063 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00907223 |
| TUBA4A | tubulin, alpha 4a | 0.00897519 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00896506 |
| S100A12 | S100 calcium binding protein A12 | 0.00894216 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00891894 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00888372 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00888068 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00883402 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | 0.00882943 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.00881534 |
| BPIFA1 | BPI fold containing family A, member 1 | 0.00880693 |
| MFAP4 | microfibrillar-associated protein 4 | 0.00879486 |
| NTS | neurotensin | 0.00877773 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00874956 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00866791 |
| KLK11 | kallikrein-related peptidase 11 | 0.00866159 |
| C4BPA | complement component 4 binding protein, alpha | 0.00858204 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00857974 |
| DES | desmin | 0.00856008 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | 0.00850165 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 | 0.00849098 |
| PXDN | peroxidasin | 0.00847244 |
| KRT19 | keratin 19, type I | 0.00846341 |
| CLDN10 | claudin 10 | 0.00845394 |
| TESC | tescalcin | 0.00843231 |
| KLK8 | kallikrein-related peptidase 8 | 0.00841575 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00838958 |
| MYBPC1 | myosin binding protein C, slow type | 0.0083617 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00833287 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00822228 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00821817 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.008189 |
| KLF6 | Kruppel-like factor 6 | 0.008189 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.00815931 |
| PCP4 | Purkinje cell protein 4 | 0.00815842 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.00814555 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.00813777 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00812116 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00812043 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00804854 |
| NFIB | nuclear factor I/B | 0.00803322 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 0.0080076 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | 0.00797789 |
| HMGB3 | high mobility group box 3 | 0.00792948 |
| GPX3 | glutathione peroxidase 3 | 0.00792704 |
| TFRC | transferrin receptor | 0.00787335 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00784707 |
| XPO7 | exportin 7 | 0.00783612 |
| PMM2 | phosphomannomutase 2 | 0.00783062 |
| SPRR3 | small proline-rich protein 3 | 0.00782431 |
| S100A11 | S100 calcium binding protein A11 | 0.00778981 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00778349 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00777316 |
| PRDX2 | peroxiredoxin 2 | 0.00775688 |
| EPS8L2 | EPS8-like 2 | 0.00774221 |
| ABLIM1 | actin binding LIM protein 1 | 0.00774177 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00773095 |
| ZNF160 | zinc finger protein 160 | 0.00770243 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.00769644 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.00768675 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00767093 |
| PDZD2 | PDZ domain containing 2 | 0.00766856 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00765887 |
| THYN1 | thymocyte nuclear protein 1 | 0.00764823 |
| CADM1 | cell adhesion molecule 1 | 0.00763194 |
| CDA | cytidine deaminase | 0.00763053 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 0.00762104 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | 0.00761095 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00760593 |
| BMP2 | bone morphogenetic protein 2 | 0.00759941 |
| RNASET2 | ribonuclease T2 | 0.00758164 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0075793 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0075566 |
| CLU | clusterin | 0.00751246 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 0.00750872 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00749445 |
| RET | ret proto-oncogene | 0.00748153 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00746025 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00745621 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.0074445 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00743683 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00741871 |
| PRKCB | protein kinase C, beta | 0.00740982 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00739917 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.00739459 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.007389 |
| PLK2 | polo-like kinase 2 | 0.00738506 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00738366 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00738063 |
| C1R | complement component 1, r subcomponent | 0.00737267 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00736815 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00736411 |
| ABHD2 | abhydrolase domain containing 2 | 0.00735455 |
| ADM | adrenomedullin | 0.00730681 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.00728797 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00728252 |
| BSG | basigin (Ok blood group) | 0.00727516 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0072715 |
| MAB21L1 | mab-21-like 1 (C. elegans) | 0.00727022 |
| DLG5 | discs, large homolog 5 (Drosophila) | 0.00726949 |
| CNTN1 | contactin 1 | 0.00722534 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.00720149 |
| SCEL | sciellin | 0.00719817 |
| SELENBP1 | selenium binding protein 1 | 0.007197 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00718411 |
| NNMT | nicotinamide N-methyltransferase | 0.00718222 |
| AMOTL2 | angiomotin like 2 | 0.00717881 |
| SDC1 | syndecan 1 | 0.00717352 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00716591 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00714104 |
| CAV2 | caveolin 2 | 0.00713542 |
| FA2H | fatty acid 2-hydroxylase | 0.00712722 |
| MCL1 | myeloid cell leukemia 1 | 0.00710512 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00710392 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00710125 |
| MX1 | MX dynamin-like GTPase 1 | 0.00709756 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.00709442 |
| DIXDC1 | DIX domain containing 1 | 0.00708454 |
| MX2 | MX dynamin-like GTPase 2 | 0.00708406 |
| MARCKSL1 | MARCKS-like 1 | 0.00707814 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00707633 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.00707267 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 0.00705606 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00705428 |
| TAGLN | transgelin | 0.00704547 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00704389 |
| KRT7 | keratin 7, type II | 0.00701963 |
| KRT8 | keratin 8, type II | 0.00701228 |
| CALCA | calcitonin-related polypeptide alpha | 0.0069658 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00695341 |
| CDCA4 | cell division cycle associated 4 | 0.00695338 |
| SETBP1 | SET binding protein 1 | 0.0069191 |
| STOM | stomatin | 0.00691728 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00690999 |
| RREB1 | ras responsive element binding protein 1 | 0.00690468 |
| SGCE | sarcoglycan, epsilon | 0.00690192 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00689913 |
| INHBB | inhibin, beta B | 0.0068909 |
| CFB | complement factor B | 0.00688669 |
| KRT18 | keratin 18, type I | 0.00685206 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00685054 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00683554 |
| PTHLH | parathyroid hormone-like hormone | 0.00682554 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.00681819 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00681012 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00680584 |
| RPS17 | ribosomal protein S17 | 0.00679806 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.00679485 |
| NES | nestin | 0.00678984 |
| MB | myoglobin | 0.00678146 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00677123 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00676669 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00675149 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00675019 |
| CPD | carboxypeptidase D | 0.00675014 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00674631 |
| DPT | dermatopontin | 0.00673919 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00673259 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 | 0.00672697 |
| FBXW12 | F-box and WD repeat domain containing 12 | 0.00672001 |
| CTSG | cathepsin G | 0.00670481 |
| RTN3 | reticulon 3 | 0.0067028 |
| HBB | hemoglobin, beta | 0.00670213 |
| NOTCH2NL | notch 2 N-terminal like | 0.00669946 |
| GOLGA8H | golgin A8 family, member H | 0.00669696 |
| OPHN1 | oligophrenin 1 | 0.00669297 |
| LBH | limb bud and heart development | 0.0066747 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00666444 |
| CHGB | chromogranin B | 0.00666441 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | 0.00666429 |
| CD4 | CD4 molecule | 0.0066408 |
| CDC42 | cell division cycle 42 | 0.006633 |
| MT1E | metallothionein 1E | 0.00662495 |
| THBS4 | thrombospondin 4 | 0.00661966 |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 | 0.00661084 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00660541 |
| CUX2 | cut-like homeobox 2 | 0.00659449 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00659356 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00659116 |
| HOMER3 | homer scaffolding protein 3 | 0.00658566 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00657791 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.00656731 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.00656378 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00655029 |
| DSTN | destrin (actin depolymerizing factor) | 0.00654573 |
| ACD | adrenocortical dysplasia homolog (mouse) | 0.00651457 |
| IRS1 | insulin receptor substrate 1 | 0.00651204 |
| EMX2 | empty spiracles homeobox 2 | 0.0064974 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00648957 |
| EZR | ezrin | 0.00648458 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.00648377 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.0064804 |
| ARHGAP6 | Rho GTPase activating protein 6 | 0.00646307 |
| HYAL1 | hyaluronoglucosaminidase 1 | 0.00646245 |
| CAPN6 | calpain 6 | 0.00645682 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MEF2C | myocyte enhancer factor 2C | -0.0178521 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0165807 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0161339 |
| H1-2 | H1.2 linker histone, cluster member | -0.0145937 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.0133479 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.0133349 |
| PRR7 | proline rich 7 (synaptic) | -0.0124052 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0123038 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.0119826 |
| HIST1H2AC | histone cluster 1, H2ac | -0.0118127 |
| LOX | lysyl oxidase | -0.0116244 |
| HIST1H2BD | histone cluster 1, H2bd | -0.0114953 |
| EGR1 | early growth response 1 | -0.0113175 |
| KRT16 | keratin 16, type I | -0.0112898 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.0109508 |
| MMP9 | matrix metallopeptidase 9 | -0.0108197 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.0107848 |
| ATF3 | activating transcription factor 3 | -0.0107249 |
| BTG3 | BTG family, member 3 | -0.0106806 |
| KLK7 | kallikrein-related peptidase 7 | -0.0104562 |
| ZNF395 | zinc finger protein 395 | -0.010429 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.0104116 |
| S100A7 | S100 calcium binding protein A7 | -0.0102308 |
| RCAN1 | regulator of calcineurin 1 | -0.0101697 |
| STC2 | stanniocalcin 2 | -0.0100306 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.0100018 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00996503 |
| CD69 | CD69 molecule | -0.00992552 |
| CD52 | CD52 molecule | -0.00986514 |
| CTSK | cathepsin K | -0.00983411 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00976445 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | -0.00972346 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00970942 |
| S100A2 | S100 calcium binding protein A2 | -0.00942711 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00936558 |
| CD48 | CD48 molecule | -0.00931988 |
| NVL | nuclear VCP-like | -0.00925519 |
| E2F2 | E2F transcription factor 2 | -0.0092504 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00921664 |
| ITGA6 | integrin, alpha 6 | -0.0091575 |
| LOXL1 | lysyl oxidase-like 1 | -0.00913884 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00913115 |
| KRT17 | keratin 17, type I | -0.00910198 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00902311 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00894344 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00890718 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00889326 |
| NPR3 | natriuretic peptide receptor 3 | -0.00886463 |
| KRT14 | keratin 14, type I | -0.00886327 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00883627 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00867381 |
| FZD6 | frizzled class receptor 6 | -0.00866255 |
| CLGN | calmegin | -0.00865382 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00857492 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.008511 |
| MMP11 | matrix metallopeptidase 11 | -0.0084627 |
| PFKP | phosphofructokinase, platelet | -0.0084359 |
| CD8A | CD8a molecule | -0.0084171 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00838451 |
| KLF2 | Kruppel-like factor 2 | -0.00835721 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.0083384 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00831164 |
| KLK5 | kallikrein-related peptidase 5 | -0.00828238 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00827259 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00823753 |
| NID2 | nidogen 2 (osteonidogen) | -0.00822237 |
| PRSS21 | protease, serine, 21 (testisin) | -0.00821937 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00816757 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00806958 |
| LXN | latexin | -0.00803627 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00803336 |
| TUBA1A | tubulin, alpha 1a | -0.00796003 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00794443 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0078699 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00785707 |
| OPN3 | opsin 3 | -0.00782183 |
| MMP1 | matrix metallopeptidase 1 | -0.00776311 |
| RAP2A | RAP2A, member of RAS oncogene family | -0.00776131 |
| WDR26 | WD repeat domain 26 | -0.00775317 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.00774334 |
| KRT81 | keratin 81, type II | -0.00774016 |
| IRF1 | interferon regulatory factor 1 | -0.00773105 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00772215 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.00771817 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -0.00771729 |
| TMEM38B | transmembrane protein 38B | -0.00768701 |
| HOXD3 | homeobox D3 | -0.0076748 |
| MLPH | melanophilin | -0.00767037 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00766066 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00765708 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00763978 |
| VIM | vimentin | -0.00762972 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.00762878 |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 | -0.00762552 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.00759214 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00758495 |
| ABHD4 | abhydrolase domain containing 4 | -0.0075695 |
| SVIL | supervillin | -0.00756863 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00756084 |
| THAP12 | THAP domain containing 12 | -0.0075568 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.00754989 |
| PLN | phospholamban | -0.00754338 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.00744915 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00739798 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.00739262 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -0.00738418 |
| DAXX | death-domain associated protein | -0.00736571 |
| CD34 | CD34 molecule | -0.00736541 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -0.00735842 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00735734 |
| TOM1L1 | target of myb1 (chicken)-like 1 | -0.00733124 |
| LMBRD1 | LMBR1 domain containing 1 | -0.00732054 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00729865 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -0.00729726 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00728324 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00725911 |
| CCNG2 | cyclin G2 | -0.00725087 |
| H1-10 | H1.10 linker histone | -0.00725067 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.00721363 |
| CD44 | CD44 molecule (Indian blood group) | -0.00721123 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00720315 |
| MOK | MOK protein kinase | -0.00718481 |
| LRRC1 | leucine rich repeat containing 1 | -0.00717272 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.0071721 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00716615 |
| RC3H2 | ring finger and CCCH-type domains 2 | -0.00715971 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | -0.00715703 |
| CCDC92 | coiled-coil domain containing 92 | -0.00715508 |
| KIAA0125 | KIAA0125 | -0.0071325 |
| MLF1 | myeloid leukemia factor 1 | -0.00713075 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.00712379 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00710639 |
| FAM162A | family with sequence similarity 162, member A | -0.0071052 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0070521 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00704026 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00702264 |
| TSPAN7 | tetraspanin 7 | -0.00700573 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.00697414 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00695492 |
| CD300A | CD300a molecule | -0.00692662 |
| CTSV | cathepsin V | -0.00691525 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.0068972 |
| CLDN3 | claudin 3 | -0.00689045 |
| ADIRF | adipogenesis regulatory factor | -0.00688865 |
| MYOT | myotilin | -0.00686934 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.00686844 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00685327 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0068237 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -0.00682083 |
| COCH | cochlin | -0.00679816 |
| LRRC17 | leucine rich repeat containing 17 | -0.00678924 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00678072 |
| TSPYL5 | TSPY-like 5 | -0.00677625 |
| LYPD1 | LY6/PLAUR domain containing 1 | -0.0067758 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00676682 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00676308 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00676156 |
| ANXA4 | annexin A4 | -0.00675038 |
| EMP1 | epithelial membrane protein 1 | -0.00672388 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.00672095 |
| KIFAP3 | kinesin-associated protein 3 | -0.00670987 |
| SARS1 | seryl-tRNA synthetase 1 | -0.00670877 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.00669351 |
| TOGARAM1 | TOG array regulator of axonemal microtubules 1 | -0.00667752 |
| EFNB2 | ephrin-B2 | -0.00666916 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | -0.00666731 |
| TSPAN8 | tetraspanin 8 | -0.00665246 |
| RORA | RAR-related orphan receptor A | -0.00665094 |
| CD9 | CD9 molecule | -0.00663301 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.00663063 |
| COMP | cartilage oligomeric matrix protein | -0.00662981 |
| F12 | coagulation factor XII (Hageman factor) | -0.00662702 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.00660855 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00660287 |
| COL10A1 | collagen, type X, alpha 1 | -0.0065825 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00658015 |
| CTBP2 | C-terminal binding protein 2 | -0.00657478 |
| CLIC5 | chloride intracellular channel 5 | -0.00657115 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.00656123 |
| SAR1B | secretion associated, Ras related GTPase 1B | -0.00655621 |
| NRN1 | neuritin 1 | -0.00654415 |
| BCL2A1 | BCL2-related protein A1 | -0.00654186 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00653927 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00653874 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00648338 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | -0.00646553 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00646261 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00645971 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | -0.00645182 |
| GRAMD2B | GRAM domain containing 2B | -0.00644052 |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 | -0.00642843 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.00641686 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.00640893 |
| LEPROT | leptin receptor overlapping transcript | -0.00639444 |
| TMEM106B | transmembrane protein 106B | -0.00638764 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | -0.00635893 |
| CCNG1 | cyclin G1 | -0.00635234 |
| SLC25A46 | solute carrier family 25, member 46 | -0.00633497 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.0063231 |
| FMO1 | flavin containing monooxygenase 1 | -0.00631249 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00629723 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00629703 |
| NSL1 | NSL1, MIS12 kinetochore complex component | -0.00629602 |
| KLK3 | kallikrein-related peptidase 3 | -0.00629311 |
| MSMB | microseminoprotein, beta- | -0.00628885 |
| TIPRL | TOR signaling pathway regulator | -0.00628741 |
| C6ORF48 | chromosome 6 open reading frame 48 | -0.00627739 |
| KRT5 | keratin 5, type II | -0.0062742 |
| TNS3 | tensin 3 | -0.00627356 |
| ITM2C | integral membrane protein 2C | -0.00626673 |
| MMP12 | matrix metallopeptidase 12 | -0.00625897 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.00625648 |
| STK10 | serine/threonine kinase 10 | -0.00625518 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 | -0.00623832 |
| C21ORF91 | chromosome 21 open reading frame 91 | -0.00623011 |
| PITX3 | paired-like homeodomain 3 | -0.00622696 |
| CPE | carboxypeptidase E | -0.00622238 |
| SNX13 | sorting nexin 13 | -0.0061881 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.00618604 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00615643 |
| KLK2 | kallikrein-related peptidase 2 | -0.00615392 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00615264 |
| PIR | pirin (iron-binding nuclear protein) | -0.00614952 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00614767 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00613533 |
| KLHL41 | kelch-like family member 41 | -0.00613198 |
| MMRN1 | multimerin 1 | -0.00612157 |
