E2F6 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description E2F transcription factor 6|This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] (NCBI Entrez Gene Database, 1876)
External Link http://www.ncbi.nlm.nih.gov/gene/1876
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Genes

63 interacting proteins for E2F6 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
APP amyloid beta (A4) precursor protein
ARAF A-Raf proto-oncogene, serine/threonine kinase
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
BMI1 BMI1 proto-oncogene, polycomb ring finger
C17ORF49 chromosome 17 open reading frame 49
CBX3 chromobox homolog 3
CHD8 chromodomain helicase DNA binding protein 8
CHEK1 checkpoint kinase 1
E2F1 E2F transcription factor 1
EED embryonic ectoderm development
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EPC1 enhancer of polycomb homolog 1 (Drosophila)
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
HCFC1 host cell factor C1
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
INO80C INO80 complex subunit C
KANSL1 KAT8 regulatory NSL complex subunit 1
KAT8 K(lysine) acetyltransferase 8
KDM5C lysine (K)-specific demethylase 5C
KMT2A lysine (K)-specific methyltransferase 2A
KMT2D lysine (K)-specific methyltransferase 2D
L3MBTL1 l(3)mbt-like 1 (Drosophila)
L3MBTL2 l(3)mbt-like 2 (Drosophila)
L3MBTL3 l(3)mbt-like 3 (Drosophila)
LAS1L LAS1-like (S. cerevisiae)
LYN LYN proto-oncogene, Src family tyrosine kinase
MAX MYC associated factor X
MCRS1 microspherule protein 1
MGA MGA, MAX dimerization protein
NCOR1 nuclear receptor corepressor 1
NRF1 nuclear respiratory factor 1
PCGF2 polycomb group ring finger 2
PCGF6 polycomb group ring finger 6
PELP1 proline, glutamate and leucine rich protein 1
PHF20 PHD finger protein 20
PRPF31 pre-mRNA processing factor 31
RBBP5 retinoblastoma binding protein 5
REEP5 receptor accessory protein 5
REST RE1-silencing transcription factor
RING1 ring finger protein 1
RNF2 ring finger protein 2
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
RYBP RING1 and YY1 binding protein
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TEX10 testis expressed 10
TFDP1 transcription factor Dp-1
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
UBC ubiquitin C
WDR5 WD repeat domain 5
YAF2 YY1 associated factor 2
ZMYND11 zinc finger, MYND-type containing 11
ZMYND8 zinc finger, MYND-type containing 8