ECM proteoglycans Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-3000178
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Genes

76 proteins participating in the ECM proteoglycans pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ACAN aggrecan
AGRN agrin
APP amyloid beta (A4) precursor protein
ASPN asporin
BCAN brevican
BGN biglycan
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL2A1 collagen, type II, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A4 collagen, type IV, alpha 4
COL4A5 collagen, type IV, alpha 5
COL4A6 collagen, type IV, alpha 6
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
COL5A3 collagen, type V, alpha 3
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
COL6A3 collagen, type VI, alpha 3
COL6A5 collagen, type VI, alpha 5
COL6A6 collagen, type VI, alpha 6
COL9A1 collagen, type IX, alpha 1
COL9A2 collagen, type IX, alpha 2
COL9A3 collagen, type IX, alpha 3
COMP cartilage oligomeric matrix protein
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCN decorin
DMP1 dentin matrix acidic phosphoprotein 1
DSPP dentin sialophosphoprotein
FMOD fibromodulin
FN1 fibronectin 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HSPG2 heparan sulfate proteoglycan 2
IBSP integrin-binding sialoprotein
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA7 integrin, alpha 7
ITGA8 integrin, alpha 8
ITGA9 integrin, alpha 9
ITGAV integrin, alpha V
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB5 integrin, beta 5
ITGB6 integrin, beta 6
LAMA1 laminin, alpha 1
LAMA2 laminin, alpha 2
LAMA3 laminin, alpha 3
LAMA4 laminin, alpha 4
LAMA5 laminin, alpha 5
LAMB1 laminin, beta 1
LAMB2 laminin, beta 2 (laminin S)
LAMC1 laminin, gamma 1 (formerly LAMB2)
LRP4 low density lipoprotein receptor-related protein 4
LUM lumican
MATN1 matrilin 1, cartilage matrix protein
MATN3 matrilin 3
MATN4 matrilin 4
MUSK muscle, skeletal, receptor tyrosine kinase
NCAM1 neural cell adhesion molecule 1
NCAN neurocan
PTPRS protein tyrosine phosphatase, receptor type, S
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TNC tenascin C
TNN tenascin N
TNR tenascin R
TNXB tenascin XB
VCAN versican
VTN vitronectin