ECSIT Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description ECSIT signalling integrator| (NCBI Entrez Gene Database, 51295)
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Genes

351 genes differentially expressed following the ECSIT gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ERVW-1 endogenous retrovirus group W, member 1 3.02351
PXT1 peroxisomal, testis specific 1 3.02351
ARL5C ADP-ribosylation factor-like 5C 3.02351
APOH apolipoprotein H (beta-2-glycoprotein I) 3.02351
OSTN osteocrin 3.02351
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.02351
ATP13A4 ATPase type 13A4 3.02351
NR1I3 nuclear receptor subfamily 1, group I, member 3 3.02351
PKD1L1 polycystic kidney disease 1 like 1 3.02351
C1ORF141 chromosome 1 open reading frame 141 3.02351
CD300LF CD300 molecule-like family member f 3.02351
DIO1 deiodinase, iodothyronine, type I 3.02351
PRDM12 PR domain containing 12 3.02351
MYADML2 myeloid-associated differentiation marker-like 2 3.02351
RNF17 ring finger protein 17 3.02351
LRRN4 leucine rich repeat neuronal 4 3.02351
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 3.02351
CD226 CD226 molecule 3.02351
TRPM1 transient receptor potential cation channel, subfamily M, member 1 3.02351
THRSP thyroid hormone responsive 3.02351
SLC46A2 solute carrier family 46, member 2 3.02351
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 3.02351
CD1D CD1d molecule 3.02351
BSX brain-specific homeobox 2.89838
TBATA thymus, brain and testes associated 2.89838
PTGER3 prostaglandin E receptor 3 (subtype EP3) 2.89838
IFI6 interferon, alpha-inducible protein 6 2.89838
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 2.89838
WNT8B wingless-type MMTV integration site family, member 8B 2.89838
ANXA10 annexin A10 2.89838
MRC1 mannose receptor, C type 1 2.89838
PRR18 proline rich 18 2.89838
GPR179 G protein-coupled receptor 179 2.89838
IL17D interleukin 17D 2.89838
LKAAEAR1 LKAAEAR motif containing 1 2.89838
TSSK1B testis-specific serine kinase 1B 2.89838
ZC3H11B zinc finger CCCH-type containing 11B pseudogene 2.89838
SLC26A4 solute carrier family 26 (anion exchanger), member 4 2.89838
MYOT myotilin 2.89838
FAM81B family with sequence similarity 81, member B 2.89838
GZMM granzyme M (lymphocyte met-ase 1) 2.89838
RNASE7 ribonuclease, RNase A family, 7 2.89838
OR2A12 olfactory receptor, family 2, subfamily A, member 12 2.89838
SCRT1 scratch family zinc finger 1 2.89838
SPAG8 sperm associated antigen 8 2.89838
SIM2 single-minded family bHLH transcription factor 2 2.89838
SPACA5 sperm acrosome associated 5 2.89838
IL37 interleukin 37 2.89838
TPSD1 tryptase delta 1 2.89838
DDN dendrin 2.89838
UNC13C unc-13 homolog C (C. elegans) 2.89838
HORMAD1 HORMA domain containing 1 2.89838
AKAP6 A kinase (PRKA) anchor protein 6 2.89838
TM4SF1 transmembrane 4 L six family member 1 2.89838
PCDHB4 protocadherin beta 4 2.89838
SPINK6 serine peptidase inhibitor, Kazal type 6 2.89838
PLIN4 perilipin 4 2.89838
IGFL3 IGF-like family member 3 2.89838
UPK3B uroplakin 3B 2.89838
SELPLG selectin P ligand 2.89838
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 2.89838
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 2.89838
FAM167A family with sequence similarity 167, member A 2.89838
NPAP1 nuclear pore associated protein 1 2.89838
SLC22A14 solute carrier family 22, member 14 2.89838
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 2.89838
TEX101 testis expressed 101 2.89838
TRPV3 transient receptor potential cation channel, subfamily V, member 3 2.89838
DEFB106B defensin, beta 106B 2.89838
OR9H1 olfactory receptor family 9 subfamily H member 1 pseudogene (gene/pseudogene) 2.89838
SLC23A3 solute carrier family 23, member 3 2.89838
PBOV1 prostate and breast cancer overexpressed 1 2.89838
SFXN3 sideroflexin 3 2.89838
RSPO1 R-spondin 1 2.89838
EIF5B eukaryotic translation initiation factor 5B 2.89838
ASB17 ankyrin repeat and SOCS box containing 17 2.89838
TAS2R31 taste receptor, type 2, member 31 2.89838
FAM153A family with sequence similarity 153, member A 2.89838
TBX22 T-box 22 2.89838
SH2D6 SH2 domain containing 6 2.89838
CXORF65 chromosome X open reading frame 65 2.89838
CLEC12A C-type lectin domain family 12, member A 2.89838
CSNK2A2IP casein kinase 2 subunit alpha' interacting protein 2.89838
PRH2 proline-rich protein HaeIII subfamily 2 2.89838
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 2.89838
RBM20 RNA binding motif protein 20 2.89838
C3AR1 complement component 3a receptor 1 2.89838
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 2.89838
RPL37A ribosomal protein L37a 2.89838
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 2.89838
TEX19 testis expressed 19 2.89838
IL1B interleukin 1, beta 2.89838
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 2.89838
IFITM5 interferon induced transmembrane protein 5 2.89838
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 2.89838
RHCG Rh family, C glycoprotein 2.89838
XRRA1 X-ray radiation resistance associated 1 2.89838
APOC4 apolipoprotein C-IV 2.89838
RPL24 ribosomal protein L24 2.89838
PDE4D phosphodiesterase 4D, cAMP-specific 2.89838
FLRT3 fibronectin leucine rich transmembrane protein 3 2.89838
FAM240C family with sequence similarity 240 member C 2.89838
MEPE matrix extracellular phosphoglycoprotein 2.89838
C17ORF113 chromosome 17 open reading frame 113 2.89838
CPN2 carboxypeptidase N, polypeptide 2 2.89838
GLYATL1B glycine-N-acyltransferase like 1B 2.89838
DIPK1C divergent protein kinase domain 1C 2.89838
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 2.89838
POU4F1 POU class 4 homeobox 1 2.89838
RNF227 ring finger protein 227 2.89838
SLN sarcolipin 2.89838
DERPC DERPC proline and glycine rich nuclear protein 2.89838
EFCAB12 EF-hand calcium binding domain 12 2.89838
NOP53 NOP53 ribosome biogenesis factor 2.89838
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.89838
LRRC25 leucine rich repeat containing 25 2.89838
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.89838
HSPA8 heat shock 70kDa protein 8 2.89838
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 2.89838
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 2.89838
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 2.89838
CYBB cytochrome b-245, beta polypeptide 2.89838
CEACAM16 carcinoembryonic antigen-related cell adhesion molecule 16 2.89838
HCAR1 hydroxycarboxylic acid receptor 1 2.89838
IL12B interleukin 12B 2.89838
SBSN suprabasin 2.89838
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.89838
POU3F3 POU class 3 homeobox 3 2.89838
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.89838
MT1A metallothionein 1A 2.89838
CHRM1 cholinergic receptor, muscarinic 1 2.89838
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 2.89838
ZBED6 zinc finger, BED-type containing 6 2.89838
CD8B CD8b molecule 2.89838
TEX38 testis expressed 38 2.89838
MSANTD1 Myb/SANT-like DNA-binding domain containing 1 2.89838
PLB1 phospholipase B1 2.89838
NPPA natriuretic peptide A 2.89838
CD5L CD5 molecule-like 2.89838
F2RL3 coagulation factor II (thrombin) receptor-like 3 2.89838
TDRD15 tudor domain containing 15 2.89838
MYL10 myosin, light chain 10, regulatory 2.89838
CPSF4L cleavage and polyadenylation specific factor 4-like 2.89838
CRYBB3 crystallin, beta B3 2.89838
AQP6 aquaporin 6, kidney specific 2.89838
PIH1D2 PIH1 domain containing 2 2.89838
KHDC1L KH homology domain containing 1-like 2.89838
CTAGE15 CTAGE family, member 15 2.89838
LRRC71 leucine rich repeat containing 71 2.89838
SOWAHD sosondowah ankyrin repeat domain family member D 2.89838
KCNK9 potassium channel, two pore domain subfamily K, member 9 2.89838
KCNK4 potassium channel, two pore domain subfamily K, member 4 2.89838
IL17REL interleukin 17 receptor E-like 2.89838
SPG11 spastic paraplegia 11 (autosomal recessive) 2.89838
CELA2A chymotrypsin-like elastase family, member 2A 2.89838
VAMP5 vesicle-associated membrane protein 5 2.87313
POLR1D polymerase (RNA) I polypeptide D, 16kDa 2.87313
CUL7 cullin 7 2.84438
NOTCH4 notch 4 2.82539
EEF1AKMT2 EEF1A lysine methyltransferase 2 2.81575
PLA2G10 phospholipase A2, group X 2.80513
BLTP1 bridge-like lipid transfer protein family member 1 2.80513
SDHAF3 succinate dehydrogenase complex assembly factor 3 2.77936
BAG2 BCL2-associated athanogene 2 2.77376
CCR5AS CCR5 antisense RNA 2.74574
SCG5 secretogranin V 2.74574
MPHOSPH9 M-phase phosphoprotein 9 2.67716
ATR ATR serine/threonine kinase 2.66036
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 2.63732
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 2.63151
TPST1 tyrosylprotein sulfotransferase 1 2.63151
FTO fat mass and obesity associated 2.57979
PDZD7 PDZ domain containing 7 2.5713
MON2 MON2 homolog (S. cerevisiae) 2.57033
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 2.55201
SLC66A3 solute carrier family 66 member 3 2.54639
NUTF2 nuclear transport factor 2 2.51559
GOLGA8H golgin A8 family, member H 2.46514
PRRT2 proline-rich transmembrane protein 2 2.44377
RBM44 RNA binding motif protein 44 2.42508
RPS18 ribosomal protein S18 2.40072
REXO2 RNA exonuclease 2 2.37969
GFUS GDP-L-fucose synthase 2.36285
FTL ferritin, light polypeptide 2.36139
SOX4 SRY (sex determining region Y)-box 4 2.35167
KIF5A kinesin family member 5A 2.34475
S100PBP S100P binding protein 2.33716
LYPLA1 lysophospholipase I 2.32161
METTL21A methyltransferase like 21A 2.32116
STEEP1 STING1 ER exit protein 1 2.30925
KMT2D lysine (K)-specific methyltransferase 2D 2.29892
CELF1 CUGBP, Elav-like family member 1 2.29331
NOM1 nucleolar protein with MIF4G domain 1 2.27561
GPR61 G protein-coupled receptor 61 2.27422
CZIB CXXC motif containing zinc binding protein 2.26805
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 2.26191
MEIG1 meiosis/spermiogenesis associated 1 2.24338
TGFB1 transforming growth factor, beta 1 2.22923
RPS19 ribosomal protein S19 2.20153
RPL34 ribosomal protein L34 2.19197
MAP1S microtubule-associated protein 1S 2.19197
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) 2.19074
BCL2L1 BCL2-like 1 2.16896
ZBTB25 zinc finger and BTB domain containing 25 2.15811
MALT1 MALT1 paracaspase 2.15811
RPL22L1 ribosomal protein L22-like 1 2.13713
ZNF507 zinc finger protein 507 2.11761
DDIAS DNA damage-induced apoptosis suppressor 2.11742
PABPC1 poly(A) binding protein, cytoplasmic 1 2.11615
SLC4A2 solute carrier family 4 (anion exchanger), member 2 2.11615
CPAP centrosome assembly and centriole elongation protein 2.10016
EIF4A2 eukaryotic translation initiation factor 4A2 2.09387
GK glycerol kinase 2.08414
RHOXF1 Rhox homeobox family, member 1 2.07645
EIF4A1 eukaryotic translation initiation factor 4A1 2.07645
COX5B cytochrome c oxidase subunit Vb 2.07645
TSPAN7 tetraspanin 7 2.07529
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 2.07404
PDZD2 PDZ domain containing 2 2.05748
S100A11 S100 calcium binding protein A11 2.05748
SSRP1 structure specific recognition protein 1 2.05526
PDCD6IP programmed cell death 6 interacting protein 2.05162
APOC1 apolipoprotein C-I 2.04165
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 2.03635
PDHX pyruvate dehydrogenase complex, component X 2.02637
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 2.02576
SUMF2 sulfatase modifying factor 2 2.02319
NPIPB4 nuclear pore complex interacting protein family, member B4 2.01578
MKI67 marker of proliferation Ki-67 2.0141
FBXL5 F-box and leucine-rich repeat protein 5 2.0141
PRKD3 protein kinase D3 2.0135
CHGB chromogranin B 2.0079
PMF1 polyamine-modulated factor 1 2.00597
FOSL1 FOS-like antigen 1 2.00258
LINC02610 long intergenic non-protein coding RNA 2610 2.00258
RPS28 ribosomal protein S28 2.00258

decreased expression

Symbol Name Standardized Value
NME8 NME/NM23 family member 8 -3.02351
FLT3LG fms-related tyrosine kinase 3 ligand -3.02351
MDH1B malate dehydrogenase 1B, NAD (soluble) -3.02351
ALOX12 arachidonate 12-lipoxygenase -3.02351
SPACDR sperm acrosome developmental regulator -3.02351
NACAD NAC alpha domain containing -3.02351
PLPPR4 phospholipid phosphatase related 4 -3.02351
PCED1A PC-esterase domain containing 1A -3.02351
DCAF12L1 DDB1 and CUL4 associated factor 12-like 1 -2.89838
TMPRSS11E transmembrane protease, serine 11E -2.89838
FOXP2 forkhead box P2 -2.89838
CCDC13 coiled-coil domain containing 13 -2.89838
ZEB2 zinc finger E-box binding homeobox 2 -2.89838
HORMAD2 HORMA domain containing 2 -2.89838
PLK5 polo-like kinase 5 -2.89838
SHE Src homology 2 domain containing E -2.89838
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -2.89838
GMFG glia maturation factor, gamma -2.89838
KLLN killin, p53-regulated DNA replication inhibitor -2.89838
NWD1 NACHT and WD repeat domain containing 1 -2.89838
ACADL acyl-CoA dehydrogenase, long chain -2.89838
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -2.89838
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 -2.89838
SLC22A25 solute carrier family 22, member 25 -2.89838
LCNL1 lipocalin-like 1 -2.89838
HCRT hypocretin (orexin) neuropeptide precursor -2.89838
CSF1 colony stimulating factor 1 (macrophage) -2.89838
NR1D1 nuclear receptor subfamily 1, group D, member 1 -2.89838
TUBA4B tubulin, alpha 4b -2.89838
ENKUR enkurin, TRPC channel interacting protein -2.89838
ACSL5 acyl-CoA synthetase long-chain family member 5 -2.89838
HTRA3 HtrA serine peptidase 3 -2.89838
SLC22A31 solute carrier family 22, member 31 -2.89838
CFAP73 cilia and flagella associated protein 73 -2.89838
ABI3 ABI family, member 3 -2.89838
GBX2 gastrulation brain homeobox 2 -2.89838
CFAP61 cilia and flagella associated protein 61 -2.89838
S100B S100 calcium binding protein B -2.89838
IL36R interleukin 36 receptor -2.89838
ISL1 ISL LIM homeobox 1 -2.89838
MPND MPN domain containing -2.89838
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -2.89838
TDRD1 tudor domain containing 1 -2.89838
KPNB1 karyopherin (importin) beta 1 -2.80042
CACNB1 calcium channel, voltage-dependent, beta 1 subunit -2.7519
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -2.7009
CPNE5 copine V -2.67838
CCR10 chemokine (C-C motif) receptor 10 -2.67838
ASB18 ankyrin repeat and SOCS box containing 18 -2.67023
FAM217B family with sequence similarity 217, member B -2.6616
IQANK1 IQ motif and ankyrin repeat containing 1 -2.66036
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 -2.63151
ARHGAP19 Rho GTPase activating protein 19 -2.63151
AVEN apoptosis, caspase activation inhibitor -2.63151
RND3 Rho family GTPase 3 -2.63151
AGAP6 ArfGAP with GTPase domain, ankyrin repeat and PH domain 6 -2.59389
F11R F11 receptor -2.51559
NRCAM neuronal cell adhesion molecule -2.50628
MAP7D2 MAP7 domain containing 2 -2.50134
PGBD4 piggyBac transposable element derived 4 -2.50134
JARID2 jumonji, AT rich interactive domain 2 -2.47886
PPP2R5D protein phosphatase 2, regulatory subunit B', delta -2.4785
OR3A2 olfactory receptor, family 3, subfamily A, member 2 -2.41312
HHIP hedgehog interacting protein -2.41188
RHOBTB1 Rho-related BTB domain containing 1 -2.40072
WFDC10B WAP four-disulfide core domain 10B -2.38121
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted -2.33716
KRAS Kirsten rat sarcoma viral oncogene homolog -2.31852
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) -2.30679
TTC21A tetratricopeptide repeat domain 21A -2.30679
FAM111A family with sequence similarity 111, member A -2.27561
SFRP1 secreted frizzled-related protein 1 -2.26805
TXNIP thioredoxin interacting protein -2.26805
ACTMAP actin maturation protease -2.22706
DOK4 docking protein 4 -2.22422
HLTF helicase-like transcription factor -2.22422
SFT2D2 SFT2 domain containing 2 -2.20153
TMA7 translation machinery associated 7 homolog (S. cerevisiae) -2.19197
AKIP1 A kinase (PRKA) interacting protein 1 -2.17266
HAPLN3 hyaluronan and proteoglycan link protein 3 -2.15811
ZIC2 Zic family member 2 -2.15811
TARDBP TAR DNA binding protein -2.15811
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -2.15554
LRRTM1 leucine rich repeat transmembrane neuronal 1 -2.15442
EIF1AX eukaryotic translation initiation factor 1A, X-linked -2.13713
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog -2.12676
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -2.11441
PDGFRL platelet-derived growth factor receptor-like -2.11389
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 -2.11327
FOXH1 forkhead box H1 -2.11142
EIF5 eukaryotic translation initiation factor 5 -2.10016
CFAP410 cilia and flagella associated protein 410 -2.07645
CDH4 cadherin 4, type 1, R-cadherin (retinal) -2.07529
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.07404
MIGA2 mitoguardin 2 -2.05748
TRIM4 tripartite motif containing 4 -2.05748
RBM7 RNA binding motif protein 7 -2.05162
FANCM Fanconi anemia, complementation group M -2.05154
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 -2.04786
UHRF1 ubiquitin-like with PHD and ring finger domains 1 -2.04786
FGFR1 fibroblast growth factor receptor 1 -2.04165
RANBP2 RAN binding protein 2 -2.04165
NOP2 NOP2 nucleolar protein -2.02976
NCOA6 nuclear receptor coactivator 6 -2.02909
C14ORF132 chromosome 14 open reading frame 132 -2.02909
ZIM3 zinc finger, imprinted 3 -2.02459
ALOX12B arachidonate 12-lipoxygenase, 12R type -2.0141
AZU1 azurocidin 1 -2.0141
SYPL1 synaptophysin-like 1 -2.0141
IREB2 iron-responsive element binding protein 2 -2.0141
MAGEA4 melanoma antigen family A4 -2.0141
SRSF3 serine/arginine-rich splicing factor 3 -2.0141
LOC124902694 uncharacterized LOC124902694 -2.0141
POC5 POC5 centriolar protein -2.00728
CR1L complement component (3b/4b) receptor 1-like -2.00597