| Dataset | Guide to Pharmacology Protein Ligands of Receptors |
| Category | physical interactions |
| Type | ligand (protein) |
| Description | ectodysplasin A|The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1896) |
| External Link | http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=1896 |
| Similar Terms | |
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2 receptors of the EDA ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset.
