EDA Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ectodysplasin A|The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1896)
External Link http://www.ncbi.nlm.nih.gov/gene/1896
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4 interacting proteins for EDA from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
EDA2R ectodysplasin A2 receptor
EDAR ectodysplasin A receptor
FURIN furin (paired basic amino acid cleaving enzyme)
PLN phospholamban