EED Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description embryonic ectoderm development|This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8726)
External Link https://ncbi.nlm.nih.gov/gene/8726
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Genes

498 genes differentially expressed following the EED gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
IFI27 interferon, alpha-inducible protein 27 0.0180292
CXCL8 chemokine (C-X-C motif) ligand 8 0.0166239
TUBB6 tubulin, beta 6 class V 0.016242
CA2 carbonic anhydrase II 0.0154341
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0143983
ISG20 interferon stimulated exonuclease gene 20kDa 0.0140292
ATF3 activating transcription factor 3 0.0140271
EIF5A eukaryotic translation initiation factor 5A 0.0137929
ABLIM1 actin binding LIM protein 1 0.0136217
S100P S100 calcium binding protein P 0.0135204
PI3 peptidase inhibitor 3, skin-derived 0.0132447
XIC X chromosome inactivation center 0.0131582
CXCL12 chemokine (C-X-C motif) ligand 12 0.0131502
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.013061
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.0126346
EDN3 endothelin 3 0.0123811
THBS2 thrombospondin 2 0.0121995
GPM6B glycoprotein M6B 0.011863
S100A7 S100 calcium binding protein A7 0.0117363
CRABP1 cellular retinoic acid binding protein 1 0.0116906
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.0116598
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.0115423
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.011541
SPRR3 small proline-rich protein 3 0.0115372
ANXA1 annexin A1 0.0113768
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.0110824
KRT13 keratin 13, type I 0.0110271
THBD thrombomodulin 0.011013
ELF1 E74-like factor 1 (ets domain transcription factor) 0.0107509
NRN1 neuritin 1 0.0106734
IL32 interleukin 32 0.0105937
MT1F metallothionein 1F 0.0105923
CD200 CD200 molecule 0.010553
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.0105242
MCL1 myeloid cell leukemia 1 0.0104799
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.0104475
FXYD3 FXYD domain containing ion transport regulator 3 0.0103432
SGK1 serum/glucocorticoid regulated kinase 1 0.0102479
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.010193
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.0101537
CEMIP cell migration inducing protein, hyaluronan binding 0.0101229
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.0100079
SPRR2B small proline-rich protein 2B 0.00995049
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00989516
CLIC5 chloride intracellular channel 5 0.00984377
FABP7 fatty acid binding protein 7, brain 0.00971942
PLS3 plastin 3 0.00971894
IL6ST interleukin 6 signal transducer 0.00971589
SPRR1B small proline-rich protein 1B 0.00963883
CXCL2 chemokine (C-X-C motif) ligand 2 0.00961621
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00960093
ASCL1 achaete-scute family bHLH transcription factor 1 0.00957709
MT2A metallothionein 2A 0.00950784
GPR137B G protein-coupled receptor 137B 0.00949212
CLCA4 chloride channel accessory 4 0.00944603
KLF6 Kruppel-like factor 6 0.00943685
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00942407
LY6D lymphocyte antigen 6 complex, locus D 0.00940062
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00938658
MT1X metallothionein 1X 0.00936425
MT1HL1 metallothionein 1H-like 1 0.00927001
KRT6A keratin 6A, type II 0.00920092
MYO1C myosin IC 0.00911786
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0090893
MIR22HG MIR22 host gene 0.00906098
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.0090525
TRIM22 tripartite motif containing 22 0.00896798
CXCL5 chemokine (C-X-C motif) ligand 5 0.00887926
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00887555
ERGIC2 ERGIC and golgi 2 0.00887311
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00884827
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00883399
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.0087871
KLF4 Kruppel-like factor 4 (gut) 0.00876298
C1S complement component 1, s subcomponent 0.00876177
MT1H metallothionein 1H 0.00874899
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00874789
SPRR1A small proline-rich protein 1A 0.00870748
DAZAP2 DAZ associated protein 2 0.00865207
TAC1 tachykinin, precursor 1 0.00863042
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.0086199
DMAC2L distal membrane arm assembly component 2 like 0.00861739
GCH1 GTP cyclohydrolase 1 0.00855634
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00853174
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00851734
FABP4 fatty acid binding protein 4, adipocyte 0.00850878
LMCD1 LIM and cysteine-rich domains 1 0.00850245
DSG3 desmoglein 3 0.00849969
KRT81 keratin 81, type II 0.0084107
FCGBP Fc fragment of IgG binding protein 0.0083338
TUBB2A tubulin, beta 2A class IIa 0.00832841
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.00825995
CLTB clathrin, light chain B 0.0082553
MRPL18 mitochondrial ribosomal protein L18 0.00821558
CLDND1 claudin domain containing 1 0.00819848
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00816935
MT1G metallothionein 1G 0.00815949
ADD3 adducin 3 (gamma) 0.00810984
RCAN1 regulator of calcineurin 1 0.00806655
RBM34 RNA binding motif protein 34 0.0079846
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00796875
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00796239
YIPF6 Yip1 domain family, member 6 0.00796115
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.00793622
PADI2 peptidyl arginine deiminase, type II 0.00792919
PTHLH parathyroid hormone-like hormone 0.00791659
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00784086
KRT6B keratin 6B, type II 0.0078252
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.00782252
ACKR3 atypical chemokine receptor 3 0.00781952
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00771062
PEX2 peroxisomal biogenesis factor 2 0.00770684
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.00770517
MAGT1 magnesium transporter 1 0.00768138
MRPS28 mitochondrial ribosomal protein S28 0.00767213
FOXO1 forkhead box O1 0.00766897
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 0.00763272
TPM4 tropomyosin 4 0.00762754
ZMAT3 zinc finger, matrin-type 3 0.00760869
SLC35A5 solute carrier family 35, member A5 0.00759204
CYB5R4 cytochrome b5 reductase 4 0.00758335
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.00755856
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00749948
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00748993
MAGED2 melanoma antigen family D2 0.00748902
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00748614
LUM lumican 0.00748378
CRYAB crystallin, alpha B 0.00747931
BAMBI BMP and activin membrane-bound inhibitor 0.0074769
BMP7 bone morphogenetic protein 7 0.00747661
TM4SF1 transmembrane 4 L six family member 1 0.00744573
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.00744504
KLK10 kallikrein-related peptidase 10 0.00743577
DAXX death-domain associated protein 0.00743245
AREG amphiregulin 0.00741756
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00741755
ACTB actin, beta 0.00741597
CRIP1 cysteine-rich protein 1 (intestinal) 0.00739726
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.00737674
CCN2 cellular communication network factor 2 0.007371
YIPF5 Yip1 domain family, member 5 0.00736276
GPA33 glycoprotein A33 (transmembrane) 0.00735781
PLP1 proteolipid protein 1 0.00734319
OLFML2A olfactomedin-like 2A 0.00734037
HOXB7 homeobox B7 0.0073164
GBP2 guanylate binding protein 2, interferon-inducible 0.0073145
CLEC2B C-type lectin domain family 2, member B 0.0073011
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00729741
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00724022
TMEM59 transmembrane protein 59 0.00721812
ATG5 autophagy related 5 0.00721249
MAB21L2 mab-21-like 2 (C. elegans) 0.00721186
STX7 syntaxin 7 0.00718719
PALLD palladin, cytoskeletal associated protein 0.00717663
RIPK2 receptor-interacting serine-threonine kinase 2 0.00717334
GLRX glutaredoxin (thioltransferase) 0.00716113
TRAM1 translocation associated membrane protein 1 0.0071585
SP110 SP110 nuclear body protein 0.00715425
HSPA1A heat shock 70kDa protein 1A 0.00714792
IFNGR1 interferon gamma receptor 1 0.00713489
LY96 lymphocyte antigen 96 0.0071345
LYRM2 LYR motif containing 2 0.00713387
SGCE sarcoglycan, epsilon 0.00712878
FABP1 fatty acid binding protein 1, liver 0.00712346
STOM stomatin 0.00711001
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.00710445
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.00709481
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.0070898
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.00708948
BCL2A1 BCL2-related protein A1 0.00708496
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.00705912
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.00705443
ADM adrenomedullin 0.00703932
FZD6 frizzled class receptor 6 0.00703757
TFRC transferrin receptor 0.00702547
FGF13 fibroblast growth factor 13 0.00701653
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00701612
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 0.00700614
CTTN cortactin 0.00700187
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00700058
HSPB1 heat shock 27kDa protein 1 0.00699987
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.006999
TPBG trophoblast glycoprotein 0.00698795
CREM cAMP responsive element modulator 0.0069834
RHCG Rh family, C glycoprotein 0.00697872
PRKCQ protein kinase C, theta 0.00696305
TAGLN2 transgelin 2 0.00695845
ADAM17 ADAM metallopeptidase domain 17 0.00695022
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase 0.00694319
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 0.00694293
CHMP1B charged multivesicular body protein 1B 0.00693336
ZG16 zymogen granule protein 16 0.00692488
CFI complement factor I 0.00692304
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00690692
SELENOT selenoprotein T 0.00690465
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 0.00690279
MT1E metallothionein 1E 0.00690129
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.00688124
KDM3A lysine (K)-specific demethylase 3A 0.00687471
DEFB4A defensin, beta 4A 0.00685305
GATA6 GATA binding protein 6 0.00685037
CD27 CD27 molecule 0.00684679
MME membrane metallo-endopeptidase 0.00683516
ERP44 endoplasmic reticulum protein 44 0.00682633
RPP40 ribonuclease P/MRP 40kDa subunit 0.0068184
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00681618
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00680086
FAIM Fas apoptotic inhibitory molecule 0.00678966
GHITM growth hormone inducible transmembrane protein 0.00678093
MRPL19 mitochondrial ribosomal protein L19 0.00677018
TYRP1 tyrosinase-related protein 1 0.00676805
S100A10 S100 calcium binding protein A10 0.00676677
PON2 paraoxonase 2 0.00675813
ITM2C integral membrane protein 2C 0.00672948
BEX4 brain expressed, X-linked 4 0.00672019
DEFB1 defensin, beta 1 0.00671451
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.0067097
HSPB8 heat shock 22kDa protein 8 0.00670629
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00667869
UNC45A unc-45 homolog A (C. elegans) 0.00667197
RAB29 RAB29, member RAS oncogene family 0.00666725
EDNRB endothelin receptor type B 0.00666356
PRKCH protein kinase C, eta 0.0066591
TPD52 tumor protein D52 0.00664524
PNO1 partner of NOB1 homolog (S. cerevisiae) 0.00664196
GUCY2C guanylate cyclase 2C 0.00663369
AOC1 amine oxidase, copper containing 1 0.00662787
GLTP glycolipid transfer protein 0.00662048
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 0.00661804
PLAUR plasminogen activator, urokinase receptor 0.00660074
EMP1 epithelial membrane protein 1 0.00660058
ITGA6 integrin, alpha 6 0.00659741
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.0065939
OPTN optineurin 0.00659344
RETREG1 reticulophagy regulator 1 0.00658677
TOX thymocyte selection-associated high mobility group box 0.00658585
IL1B interleukin 1, beta 0.00656825
OSTM1 osteopetrosis associated transmembrane protein 1 0.00656563
C1ORF54 chromosome 1 open reading frame 54 0.0065504
TMEM45A transmembrane protein 45A 0.00654991
MCAM melanoma cell adhesion molecule 0.00654282
FYB1 FYN binding protein 1 0.00653983
ELOVL1 ELOVL fatty acid elongase 1 0.00653683
TP53I3 tumor protein p53 inducible protein 3 0.00653385
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 0.00652999
CD59 CD59 molecule, complement regulatory protein 0.00652532
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.00651117
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.00650008
PDE4B phosphodiesterase 4B, cAMP-specific 0.00649794
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) 0.00648215

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0191551
KDM5D lysine (K)-specific demethylase 5D -0.015533
APOD apolipoprotein D -0.0139594
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.0132423
FASN fatty acid synthase -0.013123
TPSAB1 tryptase alpha/beta 1 -0.0130306
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.013018
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.011541
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.011496
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.0114074
LTF lactotransferrin -0.0108147
RTN3 reticulon 3 -0.0107457
IPO13 importin 13 -0.0105931
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0105634
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -0.0105315
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.0104914
IGFBP1 insulin-like growth factor binding protein 1 -0.0101244
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.0100736
ZBTB18 zinc finger and BTB domain containing 18 -0.0100311
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00984413
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00956992
PLXNB2 plexin B2 -0.00943592
RERE arginine-glutamic acid dipeptide (RE) repeats -0.00942797
NXN nucleoredoxin -0.00935676
ANPEP alanyl (membrane) aminopeptidase -0.00931406
AMH anti-Mullerian hormone -0.00922256
CCNF cyclin F -0.00918143
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00909857
CCDC92 coiled-coil domain containing 92 -0.00898861
KIF20A kinesin family member 20A -0.00877014
PLPP3 phospholipid phosphatase 3 -0.00874088
MLPH melanophilin -0.0085107
DVL1 dishevelled segment polarity protein 1 -0.00845497
ADCY1 adenylate cyclase 1 (brain) -0.00845289
LMNB2 lamin B2 -0.00844079
ELN elastin -0.00843523
ACACA acetyl-CoA carboxylase alpha -0.00840157
WDR7 WD repeat domain 7 -0.00835161
TBCD tubulin folding cofactor D -0.00827396
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.00809671
FST follistatin -0.00809147
MCM5 minichromosome maintenance complex component 5 -0.00802462
MACROD1 MACRO domain containing 1 -0.00798583
SETBP1 SET binding protein 1 -0.00796257
ADAM9 ADAM metallopeptidase domain 9 -0.00794243
TBC1D16 TBC1 domain family, member 16 -0.00793351
KIAA0930 KIAA0930 -0.00791322
RXRA retinoid X receptor, alpha -0.00790278
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -0.00789168
ARID1A AT rich interactive domain 1A (SWI-like) -0.00788127
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00787588
FEN1 flap structure-specific endonuclease 1 -0.00785834
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00780749
EML3 echinoderm microtubule associated protein like 3 -0.00776747
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00772916
PIP prolactin-induced protein -0.00772344
INTS1 integrator complex subunit 1 -0.00771739
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00770753
KRT7 keratin 7, type II -0.00769738
TMPRSS4 transmembrane protease, serine 4 -0.00768951
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -0.00767543
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) -0.00761964
PXN paxillin -0.0075667
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -0.00754145
EIF3B eukaryotic translation initiation factor 3, subunit B -0.00752652
CIT citron rho-interacting serine/threonine kinase -0.00750737
PRRC2A proline-rich coiled-coil 2A -0.00749121
PNKP polynucleotide kinase 3'-phosphatase -0.00748087
ABHD2 abhydrolase domain containing 2 -0.00747343
DGS2 DiGeorge syndrome/velocardiofacial syndrome complex 2 -0.00746201
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma -0.00744251
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.00743987
PRKCB protein kinase C, beta -0.0074374
CP ceruloplasmin (ferroxidase) -0.00740613
GUSB glucuronidase, beta -0.00729769
MEIS1 Meis homeobox 1 -0.00728331
TSPAN4 tetraspanin 4 -0.00728225
DPP4 dipeptidyl-peptidase 4 -0.0072679
PTN pleiotrophin -0.00725469
HMG20B high mobility group 20B -0.00724145
RPA1 replication protein A1, 70kDa -0.00724037
TTC38 tetratricopeptide repeat domain 38 -0.0072325
POLD2 polymerase (DNA directed), delta 2, accessory subunit -0.00717683
PDGFC platelet derived growth factor C -0.00716319
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00715812
CAMP cathelicidin antimicrobial peptide -0.00713936
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00712698
GTSE1 G-2 and S-phase expressed 1 -0.00708675
PRPF8 pre-mRNA processing factor 8 -0.00707292
DPYSL2 dihydropyrimidinase-like 2 -0.00703893
TRRAP transformation/transcription domain-associated protein -0.00702176
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00701713
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -0.00701421
FTH1 ferritin, heavy polypeptide 1 -0.00696821
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -0.00694821
KIF1B kinesin family member 1B -0.00692511
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) -0.00691991
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.00691333
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.00687345
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00685319
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00684897
CLGN calmegin -0.00683075
DENND4B DENN/MADD domain containing 4B -0.00682314
VARS valyl-tRNA synthetase -0.00678253
TGM2 transglutaminase 2 -0.00678004
SLIT2 slit homolog 2 (Drosophila) -0.00677968
TECR trans-2,3-enoyl-CoA reductase -0.00677922
NPY neuropeptide Y -0.00676312
CRYM crystallin, mu -0.0067527
NSD2 nuclear receptor binding SET domain protein 2 -0.00674741
ALOX5 arachidonate 5-lipoxygenase -0.00672842
FOXM1 forkhead box M1 -0.00669547
FXYD2 FXYD domain containing ion transport regulator 2 -0.00669394
COLEC12 collectin sub-family member 12 -0.00667557
RAPSN receptor-associated protein of the synapse -0.00664672
CADPS2 Ca++-dependent secretion activator 2 -0.00663559
EHMT2 euchromatic histone-lysine N-methyltransferase 2 -0.00662834
RBPMS RNA binding protein with multiple splicing -0.00661321
H2AX H2A.X variant histone -0.0066114
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -0.00660726
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00658379
TMC5 transmembrane channel-like 5 -0.00658152
MCM7 minichromosome maintenance complex component 7 -0.00656971
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00656096
PLD3 phospholipase D family, member 3 -0.00655561
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00654096
FBLN1 fibulin 1 -0.00653832
KIF15 kinesin family member 15 -0.006505
HMGB2 high mobility group box 2 -0.00649669
POLE polymerase (DNA directed), epsilon, catalytic subunit -0.00647863
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha -0.00647569
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.00645599
AKT1 v-akt murine thymoma viral oncogene homolog 1 -0.00644514
GRAMD4 GRAM domain containing 4 -0.00642225
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -0.00642129
INSIG1 insulin induced gene 1 -0.00641256
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -0.006401
CBX5 chromobox homolog 5 -0.00636936
NISCH nischarin -0.00634566
LOXL1 lysyl oxidase-like 1 -0.00633594
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00632182
BIRC5 baculoviral IAP repeat containing 5 -0.00632166
MAP2K2 mitogen-activated protein kinase kinase 2 -0.00632147
TRPV6 transient receptor potential cation channel, subfamily V, member 6 -0.00631604
RACGAP1 Rac GTPase activating protein 1 -0.00631285
IPO9 importin 9 -0.00630566
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -0.00629608
DGKZ diacylglycerol kinase, zeta -0.006293
FAM149A family with sequence similarity 149, member A -0.00627622
TOP2A topoisomerase (DNA) II alpha 170kDa -0.00627231
WNT5B wingless-type MMTV integration site family, member 5B -0.00626055
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -0.00625372
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.00624794
BCL2L1 BCL2-like 1 -0.00624442
ST18 suppression of tumorigenicity 18, zinc finger -0.00624291
SEC16A SEC16 homolog A (S. cerevisiae) -0.0062381
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -0.00622623
CRISP3 cysteine-rich secretory protein 3 -0.00622527
DAPK1 death-associated protein kinase 1 -0.00621987
MAMLD1 mastermind-like domain containing 1 -0.00621956
SMYD3 SET and MYND domain containing 3 -0.00620492
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00620171
TIMELESS timeless circadian clock -0.00617067
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.00613046
WIZ widely interspaced zinc finger motifs -0.00611641
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -0.00610954
BASP1 brain abundant, membrane attached signal protein 1 -0.00610221
THAP12 THAP domain containing 12 -0.00610009
LBR lamin B receptor -0.00608587
CAMK1 calcium/calmodulin-dependent protein kinase I -0.00608016
DEAF1 DEAF1 transcription factor -0.00607711
RBM10 RNA binding motif protein 10 -0.00607491
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00607262
AKR1C3 aldo-keto reductase family 1, member C3 -0.00604683
SAC3D1 SAC3 domain containing 1 -0.00604409
ACADVL acyl-CoA dehydrogenase, very long chain -0.0060427
NUSAP1 nucleolar and spindle associated protein 1 -0.0060418
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00603781
EXPH5 exophilin 5 -0.00601681
CD320 CD320 molecule -0.00601279
CDT1 chromatin licensing and DNA replication factor 1 -0.00599999
SCGB1D2 secretoglobin, family 1D, member 2 -0.00598913
TRIM28 tripartite motif containing 28 -0.00598905
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.0059801
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.00597747
CCR2 chemokine (C-C motif) receptor 2 -0.0059771
CNPY3 canopy FGF signaling regulator 3 -0.00597677
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.00596643
TMEM109 transmembrane protein 109 -0.00596052
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00595708
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -0.00595456
TACC3 transforming, acidic coiled-coil containing protein 3 -0.00595167
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00595013
CUX2 cut-like homeobox 2 -0.00594905
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 -0.00592975
PRC1 protein regulator of cytokinesis 1 -0.00591948
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -0.00591883
SETDB1 SET domain, bifurcated 1 -0.00591457
MEIS2 Meis homeobox 2 -0.00591005
IQSEC1 IQ motif and Sec7 domain 1 -0.00590863
NKX3-1 NK3 homeobox 1 -0.0059047
MPRIP myosin phosphatase Rho interacting protein -0.00590428
DBF4 DBF4 zinc finger -0.00589871
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.00589675
TGFB1 transforming growth factor, beta 1 -0.00587376
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00585966
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -0.00584479
SCGB2A2 secretoglobin, family 2A, member 2 -0.00584121
ESRP2 epithelial splicing regulatory protein 2 -0.0058325
MAOA monoamine oxidase A -0.00582584
RBM47 RNA binding motif protein 47 -0.00582543
PIAS3 protein inhibitor of activated STAT, 3 -0.00581897
PILRB paired immunoglobin-like type 2 receptor beta -0.00581574
SPAG5 sperm associated antigen 5 -0.00581404
PLEC plectin -0.00579845
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00579833
ARHGAP22 Rho GTPase activating protein 22 -0.00579771
ZMIZ1 zinc finger, MIZ-type containing 1 -0.00579379
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00579275
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.0057901
EFNB2 ephrin-B2 -0.00578507
MYO5C myosin VC -0.00577239
MRPL12 mitochondrial ribosomal protein L12 -0.0057574
CENPU centromere protein U -0.00575323
EIF3L eukaryotic translation initiation factor 3, subunit L -0.00574902
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.00574275
GEMIN4 gem (nuclear organelle) associated protein 4 -0.00573663
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -0.00573614
KANK2 KN motif and ankyrin repeat domains 2 -0.00573478
NVL nuclear VCP-like -0.00573455
FAAP100 FA core complex associated protein 100 -0.00571972
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -0.0057093
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) -0.0056947
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00568978
HIP1R huntingtin interacting protein 1 related -0.0056779
SLC38A10 solute carrier family 38, member 10 -0.00567589
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) -0.00567569
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae) -0.00566691
AKR1C2 aldo-keto reductase family 1, member C2 -0.00566566
PPP1R26 protein phosphatase 1, regulatory subunit 26 -0.00566433
ARHGAP33 Rho GTPase activating protein 33 -0.00565207
C6 complement component 6 -0.00565168
SIX2 SIX homeobox 2 -0.00565085
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 -0.00564034
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00563689
CCR1 chemokine (C-C motif) receptor 1 -0.00563379
PDE4A phosphodiesterase 4A, cAMP-specific -0.00562175
ZNF395 zinc finger protein 395 -0.00561829