EEF1A1 Gene Set

Dataset Hub Proteins Protein-Protein Interactions
Category physical interactions
Type hub protein
Description eukaryotic translation elongation factor 1 alpha 1|This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1915)
External Link http://www.ncbi.nlm.nih.gov/gene/1915
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Genes

168 interacting proteins for hub protein EEF1A1 from the curated Hub Proteins Protein-Protein Interactions dataset.

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACTB actin, beta
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AK6 adenylate kinase 6
ALDOA aldolase A, fructose-bisphosphate
ANKRD24 ankyrin repeat domain 24
APLP1 amyloid beta (A4) precursor-like protein 1
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARRB2 arrestin, beta 2
AXIN1 axin 1
BBS1 Bardet-Biedl syndrome 1
BBS2 Bardet-Biedl syndrome 2
BBS4 Bardet-Biedl syndrome 4
BRMS1 breast cancer metastasis suppressor 1
BTBD2 BTB (POZ) domain containing 2
C4B complement component 4B (Chido blood group)
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CASP9 caspase 9, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC130 coiled-coil domain containing 130
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CHUK conserved helix-loop-helix ubiquitous kinase
CKS2 CDC28 protein kinase regulatory subunit 2
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COX17 COX17 cytochrome c oxidase copper chaperone
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRCT1 cysteine-rich C-terminal 1
CSF1 colony stimulating factor 1 (macrophage)
CSRP2 cysteine and glycine-rich protein 2
DARS aspartyl-tRNA synthetase
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding)
DLG4 discs, large homolog 4 (Drosophila)
DYNLL1 dynein, light chain, LC8-type 1
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EGFR epidermal growth factor receptor
EIF3F eukaryotic translation initiation factor 3, subunit F
EXOSC4 exosome component 4
FAS Fas cell surface death receptor
GABARAP GABA(A) receptor-associated protein
GABARAPL1 GABA(A) receptor-associated protein like 1
GABARAPL2 GABA(A) receptor-associated protein-like 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GRB2 growth factor receptor-bound protein 2
GUSBP1 glucuronidase, beta pseudogene 1
H2AFX H2A histone family, member X
HLA-G major histocompatibility complex, class I, G
HNRNPK heterogeneous nuclear ribonucleoprotein K
HSPE1 heat shock 10kDa protein 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
ITSN1 intersectin 1 (SH3 domain protein)
JDP2 Jun dimerization protein 2
KIF1B kinesin family member 1B
LAMA4 laminin, alpha 4
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAD2L1BP MAD2L1 binding protein
MAGED2 melanoma antigen family D2
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK13 mitogen-activated protein kinase 13
MAPK14 mitogen-activated protein kinase 14
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED10 mediator complex subunit 10
MED19 mediator complex subunit 19
MED29 mediator complex subunit 29
MED9 mediator complex subunit 9
MGMT O-6-methylguanine-DNA methyltransferase
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MME membrane metallo-endopeptidase
MNAT1 MNAT CDK-activating kinase assembly factor 1
MRPL42 mitochondrial ribosomal protein L42
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
MYSM1 Myb-like, SWIRM and MPN domains 1
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NEU1 sialidase 1 (lysosomal sialidase)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PAEP progestagen-associated endometrial protein
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PASK PAS domain containing serine/threonine kinase
PCDHA4 protocadherin alpha 4
PFN2 profilin 2
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein
PLAUR plasminogen activator, urokinase receptor
PLCG1 phospholipase C, gamma 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
PQBP1 polyglutamine binding protein 1
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PSG11 pregnancy specific beta-1-glycoprotein 11
PSG9 pregnancy specific beta-1-glycoprotein 9
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB27A RAB27A, member RAS oncogene family
RAD23A RAD23 homolog A (S. cerevisiae)
RAD23B RAD23 homolog B (S. cerevisiae)
RAD52 RAD52 homolog (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAP2A RAP2A, member of RAS oncogene family
RFC5 replication factor C (activator 1) 5, 36.5kDa
RGS12 regulator of G-protein signaling 12
RNF10 ring finger protein 10
RPA2 replication protein A2, 32kDa
RPLP1 ribosomal protein, large, P1
RRAS related RAS viral (r-ras) oncogene homolog
RSRC1 arginine/serine-rich coiled-coil 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SDHAF2 succinate dehydrogenase complex assembly factor 2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SET SET nuclear proto-oncogene
SFN stratifin
SHBG sex hormone-binding globulin
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPHK1 sphingosine kinase 1
SRRM1 serine/arginine repetitive matrix 1
SRRM2 serine/arginine repetitive matrix 2
SSR1 signal sequence receptor, alpha
STMN2 stathmin 2
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SUMO2 small ubiquitin-like modifier 2
SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila)
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TGFBR1 transforming growth factor, beta receptor 1
TGIF1 TGFB-induced factor homeobox 1
TMPRSS3 transmembrane protease, serine 3
TMSB4X thymosin beta 4, X-linked
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TP53BP2 tumor protein p53 binding protein 2
TP63 tumor protein p63
TPT1 tumor protein, translationally-controlled 1
TRDMT1 tRNA aspartic acid methyltransferase 1
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae)
TSPY1 testis specific protein, Y-linked 1
TSPYL2 TSPY-like 2
TTR transthyretin
UBC ubiquitin C
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBQLN4 ubiquilin 4
VARS valyl-tRNA synthetase
VARS2 valyl-tRNA synthetase 2, mitochondrial
VCL vinculin
WARS tryptophanyl-tRNA synthetase
XPO5 exportin 5
XPOT exportin, tRNA
XRN2 5'-3' exoribonuclease 2
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBTB16 zinc finger and BTB domain containing 16
ZCCHC10 zinc finger, CCHC domain containing 10
ZNF24 zinc finger protein 24
ZPR1 ZPR1 zinc finger