| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | epidermal growth factor|This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 1950) |
| External Link | https://ncbi.nlm.nih.gov/gene/1950 |
| Similar Terms | |
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499 genes differentially expressed following the EGF gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | 0.0509824 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0405641 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 0.0368857 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0353766 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0307369 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0297056 |
| SFTPB | surfactant protein B | 0.029036 |
| GPM6B | glycoprotein M6B | 0.0286103 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.0281285 |
| LTF | lactotransferrin | 0.0276603 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.027399 |
| CADM1 | cell adhesion molecule 1 | 0.0273917 |
| ANXA3 | annexin A3 | 0.0271752 |
| MEIS2 | Meis homeobox 2 | 0.0259868 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.025123 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0245065 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0243572 |
| NEBL | nebulette | 0.0241586 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 0.0238995 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.0238968 |
| S100A7 | S100 calcium binding protein A7 | 0.0234041 |
| TYRP1 | tyrosinase-related protein 1 | 0.0232784 |
| FABP7 | fatty acid binding protein 7, brain | 0.022964 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0224876 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0223052 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.0222271 |
| CCDC86 | coiled-coil domain containing 86 | 0.0220406 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | 0.0216398 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.021476 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0214482 |
| FBXO11 | F-box protein 11 | 0.0213138 |
| NAV3 | neuron navigator 3 | 0.0212488 |
| ZIC1 | Zic family member 1 | 0.0209392 |
| RGS4 | regulator of G-protein signaling 4 | 0.0209189 |
| PLBD1 | phospholipase B domain containing 1 | 0.0207325 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.0206482 |
| REXO2 | RNA exonuclease 2 | 0.0203949 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0203562 |
| CKAP4 | cytoskeleton-associated protein 4 | 0.0203299 |
| LDHB | lactate dehydrogenase B | 0.0202105 |
| CAMP | cathelicidin antimicrobial peptide | 0.0200208 |
| APOD | apolipoprotein D | 0.0199575 |
| TJP2 | tight junction protein 2 | 0.0199558 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.0198858 |
| S100A11 | S100 calcium binding protein A11 | 0.0198718 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0197751 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.0196543 |
| MLPH | melanophilin | 0.01963 |
| DMD | dystrophin | 0.0194114 |
| PCP4 | Purkinje cell protein 4 | 0.0192289 |
| GRN | granulin | 0.0191018 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.019034 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.0190128 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0189053 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.0189005 |
| NKX2-1 | NK2 homeobox 1 | 0.0188726 |
| SFTPA2 | surfactant protein A2 | 0.018844 |
| CALML5 | calmodulin-like 5 | 0.0187779 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0187687 |
| ATP9A | ATPase, class II, type 9A | 0.0185759 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.0185363 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.0185306 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0184513 |
| TBCB | tubulin folding cofactor B | 0.0182151 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.0181553 |
| ATF3 | activating transcription factor 3 | 0.0180776 |
| VCL | vinculin | 0.0180409 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.017846 |
| CSRP1 | cysteine and glycine-rich protein 1 | 0.0178401 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.0178311 |
| FASN | fatty acid synthase | 0.0177558 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0174586 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.0174546 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.0173741 |
| TMEM131L | transmembrane 131 like | 0.0173593 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0172856 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 0.0172687 |
| ANXA1 | annexin A1 | 0.0172641 |
| VLDLR | very low density lipoprotein receptor | 0.0172021 |
| WASHC4 | WASH complex subunit 4 | 0.0171166 |
| GPR87 | G protein-coupled receptor 87 | 0.0171071 |
| BAD | BCL2-associated agonist of cell death | 0.0169904 |
| CST6 | cystatin E/M | 0.016986 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.0169085 |
| KIAA0226L | KIAA0226-like | 0.0168709 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0167237 |
| CNTN1 | contactin 1 | 0.0166898 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0166543 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.0165023 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0164661 |
| SYNGR2 | synaptogyrin 2 | 0.0164462 |
| S100A12 | S100 calcium binding protein A12 | 0.0164243 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase | 0.0164226 |
| YBX3 | Y box binding protein 3 | 0.0163792 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | 0.0163465 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.016295 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 0.0162697 |
| DDI2 | DNA-damage inducible 1 homolog 2 (S. cerevisiae) | 0.0162608 |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.016245 |
| WASF1 | WAS protein family, member 1 | 0.0162234 |
| G0S2 | G0/G1 switch 2 | 0.016154 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0160862 |
| PWP1 | PWP1 homolog (S. cerevisiae) | 0.016042 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0160003 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.0159604 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.0159523 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.015949 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | 0.015946 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 0.015928 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.015911 |
| NELFCD | negative elongation factor complex member C/D | 0.0158762 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0158657 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.0158632 |
| TSPAN13 | tetraspanin 13 | 0.0158592 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0157656 |
| DUSP6 | dual specificity phosphatase 6 | 0.0157582 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | 0.0157404 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | 0.0157274 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 | 0.0157109 |
| ZNF750 | zinc finger protein 750 | 0.0156925 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0156703 |
| NAV2 | neuron navigator 2 | 0.0156591 |
| EMX2 | empty spiracles homeobox 2 | 0.015646 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.0156371 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0156099 |
| MAGEA11 | melanoma antigen family A11 | 0.0155921 |
| HIRA | histone cell cycle regulator | 0.0154671 |
| CAPNS1 | calpain, small subunit 1 | 0.0154557 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.0154322 |
| NPY1R | neuropeptide Y receptor Y1 | 0.0153879 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.0153328 |
| BMP7 | bone morphogenetic protein 7 | 0.015316 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.0153041 |
| YME1L1 | YME1-like 1 ATPase | 0.0153039 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.0153026 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0152897 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.0152633 |
| PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 0.0152602 |
| CDSN | corneodesmosin | 0.015247 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0152289 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0152161 |
| CDC42 | cell division cycle 42 | 0.0152111 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0152033 |
| USP11 | ubiquitin specific peptidase 11 | 0.0151762 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0150215 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0149797 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.0149173 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0149094 |
| STK39 | serine threonine kinase 39 | 0.0148652 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0148504 |
| CREBBP | CREB binding protein | 0.0148014 |
| SC5D | sterol-C5-desaturase | 0.0147205 |
| CTSH | cathepsin H | 0.0146385 |
| JUNB | jun B proto-oncogene | 0.0146355 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.0145037 |
| ZC3H4 | zinc finger CCCH-type containing 4 | 0.0144474 |
| TOP1 | topoisomerase (DNA) I | 0.0144017 |
| PRAME | preferentially expressed antigen in melanoma | 0.0143479 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | 0.0143357 |
| S100B | S100 calcium binding protein B | 0.0142901 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.0142444 |
| RGS13 | regulator of G-protein signaling 13 | 0.0142335 |
| CD81 | CD81 molecule | 0.0142038 |
| KRT2 | keratin 2, type II | 0.0141933 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | 0.0141717 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0141521 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0141512 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 0.0141318 |
| LYZ | lysozyme | 0.0141293 |
| OGFRL1 | opioid growth factor receptor-like 1 | 0.0140894 |
| EI24 | etoposide induced 2.4 | 0.0140784 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.014049 |
| PLCH1 | phospholipase C, eta 1 | 0.0140275 |
| KLK5 | kallikrein-related peptidase 5 | 0.0139679 |
| NHP2 | NHP2 ribonucleoprotein | 0.0139611 |
| ERBIN | erbb2 interacting protein | 0.0139461 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | 0.0139033 |
| SPAG6 | sperm associated antigen 6 | 0.0139027 |
| TLE4 | transducin-like enhancer of split 4 | 0.0138886 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.0138797 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0138643 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | 0.0138568 |
| BDNF | brain-derived neurotrophic factor | 0.0138503 |
| SRPRA | SRP receptor subunit alpha | 0.0138238 |
| RBM42 | RNA binding motif protein 42 | 0.0138137 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 0.0138057 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0137936 |
| C1ORF56 | chromosome 1 open reading frame 56 | 0.0137934 |
| PTTG1 | pituitary tumor-transforming 1 | 0.0137898 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0137387 |
| TPD52L1 | tumor protein D52-like 1 | 0.0137211 |
| ITSN2 | intersectin 2 | 0.013694 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0136922 |
| PAX5 | paired box 5 | 0.0136798 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0136658 |
| GYG1 | glycogenin 1 | 0.0136613 |
| HOPX | HOP homeobox | 0.0136471 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0136338 |
| NEK7 | NIMA-related kinase 7 | 0.0136326 |
| ZNF652 | zinc finger protein 652 | 0.0136247 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0135949 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.0135784 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0135707 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.0135541 |
| NCAM1 | neural cell adhesion molecule 1 | 0.01351 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0134818 |
| ERGIC3 | ERGIC and golgi 3 | 0.0134757 |
| ODC1 | ornithine decarboxylase 1 | 0.0134738 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 0.0134666 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0134299 |
| MSRA | methionine sulfoxide reductase A | 0.0134175 |
| HSPA2 | heat shock 70kDa protein 2 | 0.0133985 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0133975 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | 0.0133891 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.013375 |
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 | 0.0133732 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0133723 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0133589 |
| FAM3C | family with sequence similarity 3, member C | 0.0133497 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0133481 |
| HK2 | hexokinase 2 | 0.0132743 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | 0.0132653 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.0132534 |
| AP2S1 | adaptor-related protein complex 2, sigma 1 subunit | 0.013243 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.0132187 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.0131675 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0131672 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.0131468 |
| XIC | X chromosome inactivation center | 0.0131432 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0131327 |
| FABP6 | fatty acid binding protein 6, ileal | 0.0131326 |
| DUSP2 | dual specificity phosphatase 2 | 0.0131232 |
| CSTA | cystatin A (stefin A) | 0.0130984 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0130647 |
| NDRG4 | NDRG family member 4 | 0.0130601 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.0130593 |
| C4BPA | complement component 4 binding protein, alpha | 0.0130471 |
| DCPS | decapping enzyme, scavenger | 0.0130232 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0130208 |
| PCDH9 | protocadherin 9 | 0.0130129 |
| SMYD3 | SET and MYND domain containing 3 | 0.0129724 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0129701 |
| CTSG | cathepsin G | 0.0129642 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0129602 |
| CSPG4 | chondroitin sulfate proteoglycan 4 | 0.0129584 |
| LECT2 | leukocyte cell-derived chemotaxin 2 | 0.0129422 |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 | 0.0129267 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0129137 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0129134 |
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.0128892 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -0.0496542 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -0.0352104 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0332105 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.0325199 |
| CP | ceruloplasmin (ferroxidase) | -0.0322894 |
| RBM34 | RNA binding motif protein 34 | -0.0297102 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0275223 |
| TMEM176A | transmembrane protein 176A | -0.0273014 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.0270459 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.0269319 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0267401 |
| GPX3 | glutathione peroxidase 3 | -0.0266696 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.0265274 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.0263033 |
| IL10RA | interleukin 10 receptor, alpha | -0.0262486 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0262075 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.0260861 |
| TSPAN4 | tetraspanin 4 | -0.0256533 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.025636 |
| PALLD | palladin, cytoskeletal associated protein | -0.0255188 |
| TMEM176B | transmembrane protein 176B | -0.0251964 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.024719 |
| RBM47 | RNA binding motif protein 47 | -0.0246611 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.023883 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.0234959 |
| GAS6 | growth arrest-specific 6 | -0.0234211 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.0233541 |
| CFD | complement factor D (adipsin) | -0.0232431 |
| ASS1 | argininosuccinate synthase 1 | -0.0231649 |
| RGCC | regulator of cell cycle | -0.0229713 |
| SNAI2 | snail family zinc finger 2 | -0.0228676 |
| AOC1 | amine oxidase, copper containing 1 | -0.0223605 |
| CLIC5 | chloride intracellular channel 5 | -0.0220909 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.0219684 |
| AREG | amphiregulin | -0.0219029 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.0217219 |
| RGS10 | regulator of G-protein signaling 10 | -0.021663 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0215892 |
| TADA2A | transcriptional adaptor 2A | -0.021352 |
| IFI44 | interferon-induced protein 44 | -0.0212681 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.0212377 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0209445 |
| EVI2A | ecotropic viral integration site 2A | -0.0209159 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.0209029 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.0207784 |
| NISCH | nischarin | -0.0207194 |
| COL5A1 | collagen, type V, alpha 1 | -0.0205964 |
| CHMP4A | charged multivesicular body protein 4A | -0.0204766 |
| SLAMF7 | SLAM family member 7 | -0.020476 |
| CALD1 | caldesmon 1 | -0.0204315 |
| CYTIP | cytohesin 1 interacting protein | -0.0204132 |
| IL17RB | interleukin 17 receptor B | -0.0203959 |
| MMD | monocyte to macrophage differentiation-associated | -0.0203518 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.020325 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0202085 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -0.0201802 |
| MXRA5 | matrix-remodelling associated 5 | -0.0200768 |
| LAMB1 | laminin, beta 1 | -0.019935 |
| ZBED2 | zinc finger, BED-type containing 2 | -0.0198662 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.0197753 |
| GPR65 | G protein-coupled receptor 65 | -0.0197366 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.0197163 |
| GLUL | glutamate-ammonia ligase | -0.0196813 |
| MFAP5 | microfibrillar associated protein 5 | -0.0195553 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.0195509 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0195249 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.0194863 |
| ADM | adrenomedullin | -0.0193791 |
| C1QB | complement component 1, q subcomponent, B chain | -0.0193178 |
| CFB | complement factor B | -0.0193051 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0192368 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0191539 |
| TXNIP | thioredoxin interacting protein | -0.0190462 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.0190445 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.0189511 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0189267 |
| PEG3 | paternally expressed 3 | -0.0188372 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.0187901 |
| ESR1 | estrogen receptor 1 | -0.0186657 |
| S100A14 | S100 calcium binding protein A14 | -0.0185819 |
| TST | thiosulfate sulfurtransferase (rhodanese) | -0.0185336 |
| ETHE1 | ethylmalonic encephalopathy 1 | -0.0184985 |
| RAB20 | RAB20, member RAS oncogene family | -0.0184738 |
| GPR183 | G protein-coupled receptor 183 | -0.0184595 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -0.0184205 |
| DSE | dermatan sulfate epimerase | -0.0183805 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.0183284 |
| HIST1H2AC | histone cluster 1, H2ac | -0.0182655 |
| MRFAP1L1 | Morf4 family associated protein 1-like 1 | -0.0182062 |
| COLEC12 | collectin sub-family member 12 | -0.0181259 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | -0.0181205 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | -0.0180154 |
| PXN | paxillin | -0.0179247 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | -0.0178987 |
| CD209 | CD209 molecule | -0.0178844 |
| CD86 | CD86 molecule | -0.017831 |
| SIRPA | signal-regulatory protein alpha | -0.0178273 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | -0.0177903 |
| CA12 | carbonic anhydrase XII | -0.0177227 |
| FBLN1 | fibulin 1 | -0.0176836 |
| GIMAP5 | GTPase, IMAP family member 5 | -0.0176648 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0176271 |
| MYO15B | myosin XVB | -0.0174578 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.0174034 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0173281 |
| NID2 | nidogen 2 (osteonidogen) | -0.0173141 |
| C3AR1 | complement component 3a receptor 1 | -0.0171821 |
| SHLD2 | shieldin complex subunit 2 | -0.0171296 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.0170601 |
| POP5 | processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) | -0.0170582 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | -0.0169672 |
| ACKR3 | atypical chemokine receptor 3 | -0.0169652 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0169123 |
| TTC38 | tetratricopeptide repeat domain 38 | -0.016907 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0168661 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0168589 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.0168153 |
| PLSCR3 | phospholipid scramblase 3 | -0.0167959 |
| MUC4 | mucin 4, cell surface associated | -0.0167695 |
| XCL1 | chemokine (C motif) ligand 1 | -0.0167621 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.0167308 |
| CLEC5A | C-type lectin domain family 5, member A | -0.0167172 |
| GPX2 | glutathione peroxidase 2 | -0.0166115 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.0165558 |
| PDGFD | platelet derived growth factor D | -0.0165517 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.0165052 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0164895 |
| MICALL2 | MICAL-like 2 | -0.0164544 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.0164476 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.016447 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0164352 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.0164174 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.0163516 |
| GOLM1 | golgi membrane protein 1 | -0.0163402 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -0.0163209 |
| TNS1 | tensin 1 | -0.0161803 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.0161046 |
| MEIS1 | Meis homeobox 1 | -0.0160781 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0160763 |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | -0.0160657 |
| RIDA | reactive intermediate imine deaminase A homolog | -0.016048 |
| TMEM45A | transmembrane protein 45A | -0.0160124 |
| MYLK | myosin light chain kinase | -0.0159927 |
| CALCRL | calcitonin receptor-like | -0.0159695 |
| RAB29 | RAB29, member RAS oncogene family | -0.0159522 |
| INTS8 | integrator complex subunit 8 | -0.0159368 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | -0.0159309 |
| CLEC10A | C-type lectin domain family 10, member A | -0.0159276 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | -0.015911 |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | -0.0158238 |
| TPM2 | tropomyosin 2 (beta) | -0.0158137 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.015808 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.0157936 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.015734 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -0.0156814 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.0156634 |
| BRD4 | bromodomain containing 4 | -0.0156561 |
| MKKS | McKusick-Kaufman syndrome | -0.015614 |
| COL5A2 | collagen, type V, alpha 2 | -0.0155787 |
| CA2 | carbonic anhydrase II | -0.0154509 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.01544 |
| IL1R2 | interleukin 1 receptor, type II | -0.0154076 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0154026 |
| CLEC11A | C-type lectin domain family 11, member A | -0.0153497 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0152827 |
| NELL1 | NEL-like 1 (chicken) | -0.0152813 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 | -0.0152117 |
| AGTR1 | angiotensin II receptor, type 1 | -0.0151479 |
| CD300A | CD300a molecule | -0.0151227 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.015117 |
| CARD10 | caspase recruitment domain family, member 10 | -0.0151057 |
| TMEM230 | transmembrane protein 230 | -0.0150392 |
| GSDMB | gasdermin B | -0.0150318 |
| C1QA | complement component 1, q subcomponent, A chain | -0.0150125 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.0150045 |
| VWF | von Willebrand factor | -0.0149812 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.0149037 |
| FGF9 | fibroblast growth factor 9 | -0.0148886 |
| IFI44L | interferon-induced protein 44-like | -0.014879 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | -0.0148274 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.0148267 |
| NOP56 | NOP56 ribonucleoprotein | -0.0148089 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | -0.0147789 |
| DIPK1A | divergent protein kinase domain 1A | -0.0147672 |
| SDC2 | syndecan 2 | -0.0146067 |
| VGLL4 | vestigial-like family member 4 | -0.0146045 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0145774 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.0145508 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | -0.0145373 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0144951 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.0144867 |
| CLEC2B | C-type lectin domain family 2, member B | -0.0144808 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0144644 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0144543 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0144459 |
| CES1 | carboxylesterase 1 | -0.0144445 |
| RRBP1 | ribosome binding protein 1 | -0.0144333 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0144174 |
| FECH | ferrochelatase | -0.014417 |
| CD163 | CD163 molecule | -0.0144129 |
| BTN3A2 | butyrophilin, subfamily 3, member A2 | -0.0143954 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | -0.0143703 |
| MARCH8 | membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase | -0.0143556 |
| STC1 | stanniocalcin 1 | -0.0143284 |
| IL18 | interleukin 18 | -0.0143262 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.014305 |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 | -0.0142607 |
| JOSD1 | Josephin domain containing 1 | -0.0142384 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0142149 |
| CBS | cystathionine-beta-synthase | -0.0142118 |
| VEGFC | vascular endothelial growth factor C | -0.014203 |
| HIST3H2A | histone cluster 3, H2a | -0.0141922 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0141917 |
| ABHD4 | abhydrolase domain containing 4 | -0.014182 |
| LIMK2 | LIM domain kinase 2 | -0.0141747 |
| CCR1 | chemokine (C-C motif) receptor 1 | -0.0141668 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.0141403 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.0141308 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.0141232 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -0.0141015 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0140935 |
| SLA | Src-like-adaptor | -0.0140697 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | -0.0140627 |
| CRTC3 | CREB regulated transcription coactivator 3 | -0.0140379 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | -0.0140323 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0140244 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0140129 |
| INHBB | inhibin, beta B | -0.0139924 |
| IL18RAP | interleukin 18 receptor accessory protein | -0.0139873 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.0139805 |
| SLN | sarcolipin | -0.0139762 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0139737 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 | -0.0139642 |
| FLNA | filamin A, alpha | -0.0139364 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | -0.0139316 |
| CISH | cytokine inducible SH2-containing protein | -0.0139055 |
| KAZN | kazrin, periplakin interacting protein | -0.0138941 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 | -0.0138897 |
| LAMA5 | laminin, alpha 5 | -0.0138866 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.0138818 |
| CDHR5 | cadherin-related family member 5 | -0.0138735 |
| RFC4 | replication factor C (activator 1) 4, 37kDa | -0.0138578 |
| TUBA4A | tubulin, alpha 4a | -0.0138572 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0138329 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0138243 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.0138013 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.013735 |
| PRKCH | protein kinase C, eta | -0.0137287 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -0.0136414 |
