EGFR downregulation Gene Set
Genes
26 proteins participating in the EGFR downregulation pathway from the Reactome Pathways dataset.
| Symbol |
Name |
|
AP2A1
|
adaptor-related protein complex 2, alpha 1 subunit
|
|
AP2A2
|
adaptor-related protein complex 2, alpha 2 subunit
|
|
AP2B1
|
adaptor-related protein complex 2, beta 1 subunit
|
|
AP2M1
|
adaptor-related protein complex 2, mu 1 subunit
|
|
AP2S1
|
adaptor-related protein complex 2, sigma 1 subunit
|
|
ARHGEF7
|
Rho guanine nucleotide exchange factor (GEF) 7
|
|
CBL
|
Cbl proto-oncogene, E3 ubiquitin protein ligase
|
|
CDC42
|
cell division cycle 42
|
|
CLTA
|
clathrin, light chain A
|
|
EGF
|
epidermal growth factor
|
|
EGFR
|
epidermal growth factor receptor
|
|
EPN1
|
epsin 1
|
|
EPS15
|
epidermal growth factor receptor pathway substrate 15
|
|
EPS15L1
|
epidermal growth factor receptor pathway substrate 15-like 1
|
|
GRB2
|
growth factor receptor-bound protein 2
|
|
HGS
|
hepatocyte growth factor-regulated tyrosine kinase substrate
|
|
RPS27A
|
ribosomal protein S27a
|
|
SH3GL2
|
SH3-domain GRB2-like 2
|
|
SH3KBP1
|
SH3-domain kinase binding protein 1
|
|
SPRY1
|
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
|
|
SPRY2
|
sprouty homolog 2 (Drosophila)
|
|
STAM
|
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
|
|
STAM2
|
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
|
|
UBA52
|
ubiquitin A-52 residue ribosomal protein fusion product 1
|
|
UBB
|
ubiquitin B
|
|
UBC
|
ubiquitin C
|
