EGFR downregulation Gene Set
Genes
31 proteins participating in the EGFR downregulation pathway from the Reactome Pathways 2024 dataset.
| Symbol |
Name |
|
AREG
|
amphiregulin
|
|
ARHGEF7
|
Rho guanine nucleotide exchange factor (GEF) 7
|
|
BTC
|
betacellulin
|
|
CBL
|
Cbl proto-oncogene, E3 ubiquitin protein ligase
|
|
CDC42
|
cell division cycle 42
|
|
EGF
|
epidermal growth factor
|
|
EGFR
|
epidermal growth factor receptor
|
|
EPGN
|
epithelial mitogen
|
|
EPN1
|
epsin 1
|
|
EPS15
|
epidermal growth factor receptor pathway substrate 15
|
|
EPS15L1
|
epidermal growth factor receptor pathway substrate 15-like 1
|
|
EREG
|
epiregulin
|
|
GRB2
|
growth factor receptor-bound protein 2
|
|
HBEGF
|
heparin-binding EGF-like growth factor
|
|
HGS
|
hepatocyte growth factor-regulated tyrosine kinase substrate
|
|
PTPN12
|
protein tyrosine phosphatase, non-receptor type 12
|
|
PTPN3
|
protein tyrosine phosphatase, non-receptor type 3
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
|
RPS27A
|
ribosomal protein S27a
|
|
SH3GL1
|
SH3-domain GRB2-like 1
|
|
SH3GL2
|
SH3-domain GRB2-like 2
|
|
SH3GL3
|
SH3-domain GRB2-like 3
|
|
SH3KBP1
|
SH3-domain kinase binding protein 1
|
|
SPRY1
|
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
|
|
SPRY2
|
sprouty homolog 2 (Drosophila)
|
|
STAM
|
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
|
|
STAM2
|
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
|
|
TGFA
|
transforming growth factor, alpha
|
|
UBA52
|
ubiquitin A-52 residue ribosomal protein fusion product 1
|
|
UBB
|
ubiquitin B
|
|
UBC
|
ubiquitin C
|
