| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | epidermal growth factor receptor|The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010] (NCBI Entrez Gene Database, 1956) |
| External Link | https://ncbi.nlm.nih.gov/gene/1956 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the EGFR gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPB1 | heat shock 27kDa protein 1 | 0.00794456 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00730916 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0072305 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00720655 |
| RGCC | regulator of cell cycle | 0.00719241 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00711524 |
| KRT7 | keratin 7, type II | 0.00709836 |
| S100P | S100 calcium binding protein P | 0.00686969 |
| TSPAN8 | tetraspanin 8 | 0.00682823 |
| XIC | X chromosome inactivation center | 0.00676023 |
| DIPK1A | divergent protein kinase domain 1A | 0.00669467 |
| KRT19 | keratin 19, type I | 0.00638093 |
| IL32 | interleukin 32 | 0.00636034 |
| C1S | complement component 1, s subcomponent | 0.00634508 |
| ATF3 | activating transcription factor 3 | 0.00614896 |
| JUNB | jun B proto-oncogene | 0.00611008 |
| MVP | major vault protein | 0.00598549 |
| PERP | PERP, TP53 apoptosis effector | 0.00595935 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00591342 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00587392 |
| MAGEA3 | melanoma antigen family A3 | 0.00583663 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.0057787 |
| MMP7 | matrix metallopeptidase 7 | 0.00576678 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00572958 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00565125 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00555795 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00550984 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00548343 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00548178 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00545916 |
| CSTA | cystatin A (stefin A) | 0.00536851 |
| FOLR1 | folate receptor 1 (adult) | 0.0053376 |
| YBX3 | Y box binding protein 3 | 0.0053 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00529496 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.00522956 |
| ITGB4 | integrin, beta 4 | 0.00518742 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00518243 |
| MSMB | microseminoprotein, beta- | 0.00513933 |
| RBM47 | RNA binding motif protein 47 | 0.00498574 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.00497162 |
| MME | membrane metallo-endopeptidase | 0.00494834 |
| TMEM176B | transmembrane protein 176B | 0.00473931 |
| KRT14 | keratin 14, type I | 0.00471824 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00468715 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 0.0046723 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00466671 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00464015 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | 0.00463561 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0046229 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00456861 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00456549 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00455957 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00450782 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.00448369 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00442579 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00442428 |
| JAK1 | Janus kinase 1 | 0.00441001 |
| E2F2 | E2F transcription factor 2 | 0.00440541 |
| KRT18 | keratin 18, type I | 0.00438822 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00437729 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00433748 |
| PSCA | prostate stem cell antigen | 0.0043242 |
| CRYAB | crystallin, alpha B | 0.00431652 |
| KLK10 | kallikrein-related peptidase 10 | 0.00430324 |
| C3 | complement component 3 | 0.00430179 |
| SCEL | sciellin | 0.00429904 |
| DUSP5 | dual specificity phosphatase 5 | 0.00429834 |
| HSPA2 | heat shock 70kDa protein 2 | 0.004281 |
| SIK1 | salt-inducible kinase 1 | 0.00427759 |
| CFB | complement factor B | 0.00426183 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00425238 |
| EGR1 | early growth response 1 | 0.00422455 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0042152 |
| KRT13 | keratin 13, type I | 0.00419074 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00416854 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00415576 |
| FADS3 | fatty acid desaturase 3 | 0.00412237 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.00411003 |
| S100A10 | S100 calcium binding protein A10 | 0.00409415 |
| COPS7A | COP9 signalosome subunit 7A | 0.00408092 |
| WWC1 | WW and C2 domain containing 1 | 0.00405969 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00405936 |
| MAGEA12 | melanoma antigen family A12 | 0.00405776 |
| KRT17 | keratin 17, type I | 0.00405729 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.00405544 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00405333 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.00405036 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00402062 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00400497 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.00398099 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.00397107 |
| MLF2 | myeloid leukemia factor 2 | 0.00394173 |
| DEFB1 | defensin, beta 1 | 0.00394167 |
| ABHD4 | abhydrolase domain containing 4 | 0.00393677 |
| HMOX1 | heme oxygenase 1 | 0.00392508 |
| CALB1 | calbindin 1, 28kDa | 0.00391756 |
| BAG3 | BCL2-associated athanogene 3 | 0.0038971 |
| KRT15 | keratin 15, type I | 0.00388278 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.00388068 |
| KLK11 | kallikrein-related peptidase 11 | 0.00387579 |
| CD9 | CD9 molecule | 0.00384608 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 0.00383857 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00379681 |
| PLXNB2 | plexin B2 | 0.0037816 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00378143 |
| MYBPC1 | myosin binding protein C, slow type | 0.00376412 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00376125 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00374158 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0037354 |
| EMP1 | epithelial membrane protein 1 | 0.00373536 |
| TRIM22 | tripartite motif containing 22 | 0.00373494 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00373405 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00371745 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00371568 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00370949 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00369612 |
| TPM4 | tropomyosin 4 | 0.00368448 |
| TRIM16 | tripartite motif containing 16 | 0.00365988 |
| PTGES | prostaglandin E synthase | 0.00365686 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00364084 |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.00362915 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.00361808 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00360968 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00360416 |
| ZYX | zyxin | 0.00359736 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00359223 |
| CSTB | cystatin B (stefin B) | 0.00358732 |
| DSP | desmoplakin | 0.00358653 |
| CTSD | cathepsin D | 0.00358598 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00357428 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.003572 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00356445 |
| BCL2L1 | BCL2-like 1 | 0.00355255 |
| KRT8 | keratin 8, type II | 0.00355249 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00355178 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 | 0.00353248 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00353071 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.00352903 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00352291 |
| HLA-B | major histocompatibility complex, class I, B | 0.00351616 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00351493 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 | 0.00350753 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.00350568 |
| CLDN7 | claudin 7 | 0.0034895 |
| IRS2 | insulin receptor substrate 2 | 0.00348169 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.00347424 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00347259 |
| LAMA3 | laminin, alpha 3 | 0.00347056 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00346692 |
| ATF4 | activating transcription factor 4 | 0.0034645 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00346274 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.0034588 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00345704 |
| IFI30 | interferon, gamma-inducible protein 30 | 0.00341993 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.00341662 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00339681 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00339675 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0033959 |
| LOC105375355 | uroplakin-3b | 0.00338687 |
| RRAD | Ras-related associated with diabetes | 0.00337723 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00336479 |
| GOLT1B | golgi transport 1B | 0.0033496 |
| OXTR | oxytocin receptor | 0.00334446 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00334438 |
| LHFP | lipoma HMGIC fusion partner | 0.00334217 |
| RNF167 | ring finger protein 167 | 0.00333653 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | 0.00333271 |
| MAPK13 | mitogen-activated protein kinase 13 | 0.00333229 |
| GRN | granulin | 0.0033282 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.00332551 |
| BTG2 | BTG family, member 2 | 0.00332087 |
| TFRC | transferrin receptor | 0.00331089 |
| IQCG | IQ motif containing G | 0.00330821 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00329644 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.00328088 |
| RALBP1 | ralA binding protein 1 | 0.00327349 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00327237 |
| EPS8L2 | EPS8-like 2 | 0.0032641 |
| TSPO | translocator protein (18kDa) | 0.0032608 |
| PRDX1 | peroxiredoxin 1 | 0.00325745 |
| ST8SIA1 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 | 0.00325667 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00325421 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.00325351 |
| SPRR3 | small proline-rich protein 3 | 0.00324989 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.00324613 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00324468 |
| AGR2 | anterior gradient 2 | 0.00323535 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.00322881 |
| TNNC1 | troponin C type 1 (slow) | 0.00322613 |
| NMD3 | NMD3 ribosome export adaptor | 0.00321349 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00321043 |
| MSLN | mesothelin | 0.00321035 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00319901 |
| GAB2 | GRB2-associated binding protein 2 | 0.00319418 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.00318504 |
| EIF6 | eukaryotic translation initiation factor 6 | 0.00318497 |
| TSPAN1 | tetraspanin 1 | 0.00318005 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00317857 |
| TMEM176A | transmembrane protein 176A | 0.00317537 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00317452 |
| DUSP14 | dual specificity phosphatase 14 | 0.00316991 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00316953 |
| CTSB | cathepsin B | 0.00316881 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.00316121 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0031474 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00314575 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | 0.00313827 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.00313373 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.00312363 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00312083 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 0.00310577 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.00310465 |
| CYTH2 | cytohesin 2 | 0.00309938 |
| LASP1 | LIM and SH3 protein 1 | 0.00309715 |
| HECA | headcase homolog (Drosophila) | 0.00309477 |
| CNTN1 | contactin 1 | 0.0030872 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.0030822 |
| FDXR | ferredoxin reductase | 0.00307509 |
| EPCAM | epithelial cell adhesion molecule | 0.00307425 |
| NCK1 | NCK adaptor protein 1 | 0.00307372 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.00307186 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00306897 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.00306331 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.00306176 |
| LAMB3 | laminin, beta 3 | 0.00306137 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.00305498 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | 0.00305442 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00305307 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00303855 |
| ETNK1 | ethanolamine kinase 1 | 0.00302864 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.00302807 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.00302568 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00302292 |
| OGA | O-GlcNAcase | 0.00301878 |
| MYOF | myoferlin | 0.00301781 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00301556 |
| SIRT7 | sirtuin 7 | 0.0030123 |
| IRF1 | interferon regulatory factor 1 | 0.0030105 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | 0.00301047 |
| KLK6 | kallikrein-related peptidase 6 | 0.00300974 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0030089 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.00300459 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 0.00300106 |
| TGIF1 | TGFB-induced factor homeobox 1 | 0.00299863 |
| PALLD | palladin, cytoskeletal associated protein | 0.00299412 |
| ITGA6 | integrin, alpha 6 | 0.00299352 |
| CDK7 | cyclin-dependent kinase 7 | 0.00298623 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00298506 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00298188 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00943488 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00728775 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00688753 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00665639 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00638411 |
| GPM6B | glycoprotein M6B | -0.00596477 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.0059412 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00588258 |
| THBS1 | thrombospondin 1 | -0.00583072 |
| ESR1 | estrogen receptor 1 | -0.00582153 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.0054551 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00538415 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00524069 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00521711 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00508629 |
| PROM1 | prominin 1 | -0.00503025 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.00497986 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00497818 |
| TMSB15A | thymosin beta 15a | -0.00493681 |
| SCG5 | secretogranin V | -0.00486262 |
| PRDX2 | peroxiredoxin 2 | -0.00478269 |
| HMGB2 | high mobility group box 2 | -0.00473412 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00463283 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00455592 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00451701 |
| ZW10 | zw10 kinetochore protein | -0.00450775 |
| CDC20 | cell division cycle 20 | -0.00446906 |
| OLFM4 | olfactomedin 4 | -0.00445808 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00445733 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | -0.00442691 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00442076 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00441033 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00438625 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0043543 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00432272 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | -0.00430405 |
| QKI | QKI, KH domain containing, RNA binding | -0.00425345 |
| PCP4 | Purkinje cell protein 4 | -0.00423934 |
| TNC | tenascin C | -0.00422644 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00421319 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00419683 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | -0.00419134 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00417811 |
| RNF144A | ring finger protein 144A | -0.00417607 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00417345 |
| ZG16 | zymogen granule protein 16 | -0.00416455 |
| FGL2 | fibrinogen-like 2 | -0.00415382 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00410222 |
| DNASE1L3 | deoxyribonuclease I-like 3 | -0.00405443 |
| ACKR3 | atypical chemokine receptor 3 | -0.00404515 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00401457 |
| TRMT5 | tRNA methyltransferase 5 | -0.00399044 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00398689 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | -0.00397932 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.0039691 |
| CLC | Charcot-Leyden crystal galectin | -0.00395721 |
| NNMT | nicotinamide N-methyltransferase | -0.00395559 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.00394666 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00393943 |
| PMEL | premelanosome protein | -0.00390314 |
| CLCA1 | chloride channel accessory 1 | -0.00389964 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00389685 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | -0.00389681 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00387106 |
| SRGN | serglycin | -0.00386401 |
| CD302 | CD302 molecule | -0.0038639 |
| NVL | nuclear VCP-like | -0.00385167 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | -0.00384895 |
| MCM6 | minichromosome maintenance complex component 6 | -0.00382904 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00381516 |
| S100A9 | S100 calcium binding protein A9 | -0.0038095 |
| CDCA4 | cell division cycle associated 4 | -0.00379617 |
| RPA3 | replication protein A3, 14kDa | -0.00377326 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00376017 |
| LRRC17 | leucine rich repeat containing 17 | -0.00375221 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00373568 |
| MGP | matrix Gla protein | -0.00373087 |
| NAV2 | neuron navigator 2 | -0.00372707 |
| CAMP | cathelicidin antimicrobial peptide | -0.00371966 |
| NSF | N-ethylmaleimide-sensitive factor | -0.00368781 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00368665 |
| EPHA4 | EPH receptor A4 | -0.00368625 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00368496 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.00367865 |
| CTSG | cathepsin G | -0.00366579 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.00366487 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | -0.00365917 |
| H2AFV | H2A histone family, member V | -0.00363885 |
| TYRP1 | tyrosinase-related protein 1 | -0.00363592 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00363036 |
| KIF20A | kinesin family member 20A | -0.00362698 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | -0.00362105 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00361286 |
| CPE | carboxypeptidase E | -0.00359292 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00359279 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00357211 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00357136 |
| TP73-AS1 | TP73 antisense RNA 1 | -0.00357035 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00355049 |
| FST | follistatin | -0.00354713 |
| MMP1 | matrix metallopeptidase 1 | -0.00354208 |
| LIN28A | lin-28 homolog A (C. elegans) | -0.00353624 |
| MDFIC | MyoD family inhibitor domain containing | -0.00351994 |
| CCNB2 | cyclin B2 | -0.00351816 |
| DMBT1 | deleted in malignant brain tumors 1 | -0.00351431 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | -0.00351414 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00350093 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00350042 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00349444 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00347575 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -0.00345391 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00344378 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.00344321 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.00344052 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00343501 |
| MBD1 | methyl-CpG binding domain protein 1 | -0.00342816 |
| EMP2 | epithelial membrane protein 2 | -0.00342597 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | -0.00342568 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00339547 |
| BBX | bobby sox homolog (Drosophila) | -0.00338488 |
| PLAT | plasminogen activator, tissue | -0.00338426 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00337294 |
| F2R | coagulation factor II (thrombin) receptor | -0.00337214 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) | -0.00336822 |
| TUBA1A | tubulin, alpha 1a | -0.00336683 |
| OLFM1 | olfactomedin 1 | -0.00336487 |
| COLEC12 | collectin sub-family member 12 | -0.00336128 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00335632 |
| CD96 | CD96 molecule | -0.00334552 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | -0.00334051 |
| RGS4 | regulator of G-protein signaling 4 | -0.00333127 |
| SRPRA | SRP receptor subunit alpha | -0.00333018 |
| PIMREG | PICALM interacting mitotic regulator | -0.00331599 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00331469 |
| PHF20 | PHD finger protein 20 | -0.00330051 |
| PMP22 | peripheral myelin protein 22 | -0.00330034 |
| NANOG | Nanog homeobox | -0.00329436 |
| CEP70 | centrosomal protein 70kDa | -0.00328434 |
| TMEM45A | transmembrane protein 45A | -0.00328395 |
| KIAA0100 | KIAA0100 | -0.00326929 |
| EPHB2 | EPH receptor B2 | -0.00326503 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00326467 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00326044 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.00325946 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | -0.00325752 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00325036 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.00324985 |
| FLNC | filamin C, gamma | -0.0032481 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.00324748 |
| ITM2A | integral membrane protein 2A | -0.00324661 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | -0.00323644 |
| NID2 | nidogen 2 (osteonidogen) | -0.00323247 |
| HDAC4 | histone deacetylase 4 | -0.00323179 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | -0.00322649 |
| DHFR | dihydrofolate reductase | -0.003226 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00321737 |
| TIPRL | TOR signaling pathway regulator | -0.00320841 |
| DCLK1 | doublecortin-like kinase 1 | -0.00320162 |
| LOR | loricrin | -0.0032014 |
| NID1 | nidogen 1 | -0.0031876 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -0.00318543 |
| DIAPH2 | diaphanous-related formin 2 | -0.00318512 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00318306 |
| WDR7 | WD repeat domain 7 | -0.00318184 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00316624 |
| TXNIP | thioredoxin interacting protein | -0.00315649 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | -0.0031528 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.00314819 |
| GPA33 | glycoprotein A33 (transmembrane) | -0.00314679 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | -0.00314502 |
| FAM162A | family with sequence similarity 162, member A | -0.00314074 |
| DCT | dopachrome tautomerase | -0.00313433 |
| MRTFB | myocardin related transcription factor B | -0.00313229 |
| SACS | sacsin molecular chaperone | -0.00313215 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00313125 |
| PPT1 | palmitoyl-protein thioesterase 1 | -0.00313071 |
| HPF1 | histone PARylation factor 1 | -0.0031284 |
| RSBN1 | round spermatid basic protein 1 | -0.0031267 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | -0.00311906 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | -0.00311895 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00311426 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00310783 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.00310744 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00310369 |
| GNMT | glycine N-methyltransferase | -0.00309848 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00309403 |
| LOX | lysyl oxidase | -0.00309108 |
| BNC2 | basonuclin 2 | -0.00307535 |
| CDSN | corneodesmosin | -0.0030698 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00306539 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00306115 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | -0.00304862 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.00304624 |
| HELLS | helicase, lymphoid-specific | -0.00303737 |
| BRCA1 | breast cancer 1, early onset | -0.00303568 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | -0.0030306 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.00302925 |
| LOXL2 | lysyl oxidase-like 2 | -0.00302537 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.00302383 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) | -0.00301971 |
| CPQ | carboxypeptidase Q | -0.00301927 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00300991 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.00300867 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00300661 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | -0.00299859 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00299766 |
| MDC1 | mediator of DNA-damage checkpoint 1 | -0.00299747 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.00298659 |
| DHCR7 | 7-dehydrocholesterol reductase | -0.00298472 |
| JADE1 | jade family PHD finger 1 | -0.00298208 |
| FASN | fatty acid synthase | -0.00297313 |
| CLU | clusterin | -0.00297272 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.00296943 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.00296879 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 | -0.00296682 |
| SORD | sorbitol dehydrogenase | -0.00296199 |
| SFN | stratifin | -0.00295538 |
| SAP30 | Sin3A-associated protein, 30kDa | -0.00295105 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | -0.00294949 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0029483 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase | -0.00294353 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.00294313 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0029422 |
| EIF4E | eukaryotic translation initiation factor 4E | -0.0029378 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00293008 |
| KLHL23 | kelch-like family member 23 | -0.00292846 |
| DNAAF5 | dynein, axonemal, assembly factor 5 | -0.00292682 |
| PPA2 | pyrophosphatase (inorganic) 2 | -0.00292662 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00292072 |
| CD209 | CD209 molecule | -0.00291764 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | -0.00291684 |
| BCL2A1 | BCL2-related protein A1 | -0.0029159 |
| SV2A | synaptic vesicle glycoprotein 2A | -0.00291433 |
| RPIA | ribose 5-phosphate isomerase A | -0.00291289 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | -0.0029104 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.00290684 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0029067 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00290661 |
| FANCL | Fanconi anemia, complementation group L | -0.00290524 |
| TMBIM4 | transmembrane BAX inhibitor motif containing 4 | -0.0029051 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00289603 |
| DSC1 | desmocollin 1 | -0.00289496 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.0028913 |
| MEF2C | myocyte enhancer factor 2C | -0.00288843 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | -0.00288834 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | -0.00288759 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00288365 |
| THBD | thrombomodulin | -0.00288313 |
| HAL | histidine ammonia-lyase | -0.0028827 |
| NELL2 | NEL-like 2 (chicken) | -0.00287496 |
