| Dataset | GEO Signatures of Differentially Expressed Genes for Kinase Perturbations |
| Category | transcriptomics |
| Type | kinase perturbation |
| Description | kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus) |
| External Link | http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS2146 |
| Similar Terms | |
| Downloads & Tools |
600 genes differentially expressed following the EGFR_drugactivation_19_GDS2146 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 6.67509 |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | 3.49238 |
| ELAC2 | elaC ribonuclease Z 2 | 3.09438 |
| PEX11B | peroxisomal biogenesis factor 11 beta | 2.74013 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 2.39715 |
| FAM188A | family with sequence similarity 188, member A | 2.3766 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 2.22948 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 | 2.22483 |
| GYPC | glycophorin C (Gerbich blood group) | 2.21068 |
| MYOF | myoferlin | 2.19914 |
| PXN | paxillin | 2.08119 |
| LRRC8B | leucine rich repeat containing 8 family, member B | 2.02683 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 2.00513 |
| FKBP5 | FK506 binding protein 5 | 1.90808 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 1.85764 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 1.83667 |
| PVR | poliovirus receptor | 1.8316 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 1.80231 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 1.75714 |
| RHOQ | ras homolog family member Q | 1.75417 |
| SMIM3 | small integral membrane protein 3 | 1.72775 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 1.7136 |
| CDK17 | cyclin-dependent kinase 17 | 1.68841 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 1.66668 |
| KLF13 | Kruppel-like factor 13 | 1.64281 |
| TGIF1 | TGFB-induced factor homeobox 1 | 1.64217 |
| SYMPK | symplekin | 1.61236 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 1.61115 |
| CIRH1A | cirrhosis, autosomal recessive 1A (cirhin) | 1.58189 |
| MAP2K3 | mitogen-activated protein kinase kinase 3 | 1.52811 |
| IL6ST | interleukin 6 signal transducer | 1.52088 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 1.5123 |
| PRPS1 | phosphoribosyl pyrophosphate synthetase 1 | 1.49376 |
| FBL | fibrillarin | 1.4882 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 1.47365 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 1.42799 |
| TRMT6 | tRNA methyltransferase 6 | 1.4197 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 1.40796 |
| PDPN | podoplanin | 1.40237 |
| BYSL | bystin-like | 1.39104 |
| CCNH | cyclin H | 1.38046 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | 1.37742 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 | 1.37622 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 1.36704 |
| RNF138 | ring finger protein 138, E3 ubiquitin protein ligase | 1.3401 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 1.33848 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 1.31614 |
| MLX | MLX, MAX dimerization protein | 1.31103 |
| METRNL | meteorin, glial cell differentiation regulator-like | 1.29146 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | 1.28635 |
| CLIC1 | chloride intracellular channel 1 | 1.27004 |
| UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) | 1.26802 |
| CD44 | CD44 molecule (Indian blood group) | 1.25899 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 | 1.25556 |
| WNT2 | wingless-type MMTV integration site family member 2 | 1.25526 |
| RASAL2 | RAS protein activator like 2 | 1.24454 |
| SRFBP1 | serum response factor binding protein 1 | 1.22877 |
| SLC30A7 | solute carrier family 30 (zinc transporter), member 7 | 1.22782 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 1.22533 |
| KIFC3 | kinesin family member C3 | 1.20873 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 1.20137 |
| TMX1 | thioredoxin-related transmembrane protein 1 | 1.20016 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 1.18532 |
| MTAP | methylthioadenosine phosphorylase | 1.18356 |
| BST1 | bone marrow stromal cell antigen 1 | 1.18038 |
| RNF219 | ring finger protein 219 | 1.1623 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 1.13718 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) | 1.13203 |
| STRAP | serine/threonine kinase receptor associated protein | 1.12814 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 1.10386 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 1.09975 |
| PFKP | phosphofructokinase, platelet | 1.09408 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 1.09401 |
| MCFD2 | multiple coagulation factor deficiency 2 | 1.09163 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 1.08353 |
| RPF2 | ribosome production factor 2 homolog (S. cerevisiae) | 1.07408 |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) | 1.07176 |
| TNC | tenascin C | 1.07099 |
| AXL | AXL receptor tyrosine kinase | 1.07086 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 1.05577 |
| PFDN4 | prefoldin subunit 4 | 1.05242 |
| MCL1 | myeloid cell leukemia 1 | 1.04761 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | 1.04634 |
| ETF1 | eukaryotic translation termination factor 1 | 1.03363 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 1.03293 |
| RPS24 | ribosomal protein S24 | 1.03196 |
| MAP1B | microtubule-associated protein 1B | 1.02758 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 1.02727 |
| VPS35 | vacuolar protein sorting 35 homolog (S. cerevisiae) | 1.02705 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) | 1.02681 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 1.02157 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 1.01227 |
| NR2C2AP | nuclear receptor 2C2-associated protein | 1.01084 |
| POLR3A | polymerase (RNA) III (DNA directed) polypeptide A, 155kDa | 1.00222 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.991394 |
| ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | 0.98613 |
| TJP2 | tight junction protein 2 | 0.974796 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | 0.961647 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein | 0.956444 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | 0.949395 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 | 0.925221 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.921746 |
| ERCC1 | excision repair cross-complementation group 1 | 0.905098 |
| FHL3 | four and a half LIM domains 3 | 0.901646 |
| TTLL12 | tubulin tyrosine ligase-like family member 12 | 0.891678 |
| MRPS18B | mitochondrial ribosomal protein S18B | 0.889743 |
| SNRPF | small nuclear ribonucleoprotein polypeptide F | 0.887748 |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 | 0.885458 |
| PCGF3 | polycomb group ring finger 3 | 0.885055 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 0.884177 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.881418 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.871669 |
| PRR5 | proline rich 5 (renal) | 0.868901 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | 0.865228 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.864955 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.863502 |
| UBE4B | ubiquitination factor E4B | 0.859026 |
| CERS2 | ceramide synthase 2 | 0.858148 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | 0.856362 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.853033 |
| BAIAP2 | BAI1-associated protein 2 | 0.845666 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.845167 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.84514 |
| JUN | jun proto-oncogene | 0.843972 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.841193 |
| EVA1C | eva-1 homolog C (C. elegans) | 0.840634 |
| AREG | amphiregulin | 0.840007 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.8381 |
| ADIPOR2 | adiponectin receptor 2 | 0.834701 |
| CSK | c-src tyrosine kinase | 0.831615 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.823148 |
| SLC39A13 | solute carrier family 39 (zinc transporter), member 13 | 0.821785 |
| DOK5 | docking protein 5 | 0.821231 |
| TGM1 | transglutaminase 1 | 0.821132 |
| JAGN1 | jagunal homolog 1 (Drosophila) | 0.819561 |
| MITF | microphthalmia-associated transcription factor | 0.816873 |
| MEDAG | mesenteric estrogen-dependent adipogenesis | 0.810158 |
| WBSCR22 | Williams Beuren syndrome chromosome region 22 | 0.799886 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.796256 |
| SPAG9 | sperm associated antigen 9 | 0.795551 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | 0.794159 |
| DUSP14 | dual specificity phosphatase 14 | 0.792435 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A | 0.788391 |
| COPS5 | COP9 signalosome subunit 5 | 0.787296 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.785672 |
| PCDH18 | protocadherin 18 | 0.772876 |
| SLTM | SAFB-like, transcription modulator | 0.772517 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.766802 |
| MTMR10 | myotubularin related protein 10 | 0.763742 |
| FTSJ3 | FtsJ homolog 3 (E. coli) | 0.762942 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.759193 |
| SERTAD1 | SERTA domain containing 1 | 0.758146 |
| WDR77 | WD repeat domain 77 | 0.75468 |
| SCHIP1 | schwannomin interacting protein 1 | 0.754502 |
| ESM1 | endothelial cell-specific molecule 1 | 0.753177 |
| ELMOD1 | ELMO/CED-12 domain containing 1 | 0.750295 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.74732 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.745601 |
| HIP1 | huntingtin interacting protein 1 | 0.742928 |
| ZNF639 | zinc finger protein 639 | 0.734634 |
| NMD3 | NMD3 ribosome export adaptor | 0.734383 |
| IFRD1 | interferon-related developmental regulator 1 | 0.729005 |
| TXNRD1 | thioredoxin reductase 1 | 0.726701 |
| EIF1AD | eukaryotic translation initiation factor 1A domain containing | 0.726474 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.725501 |
| DNMBP | dynamin binding protein | 0.725419 |
| NOP56 | NOP56 ribonucleoprotein | 0.722691 |
| VCL | vinculin | 0.719914 |
| GSPT1 | G1 to S phase transition 1 | 0.717707 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | 0.717056 |
| MAPK6 | mitogen-activated protein kinase 6 | 0.714075 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.709394 |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 | 0.708059 |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | 0.707999 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.707681 |
| NUS1 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) | 0.700091 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.696765 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.695386 |
| EPN2 | epsin 2 | 0.695219 |
| SOAT1 | sterol O-acyltransferase 1 | 0.694216 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 0.692932 |
| NUP62 | nucleoporin 62kDa | 0.692439 |
| ELOVL1 | ELOVL fatty acid elongase 1 | 0.692043 |
| PRMT1 | protein arginine methyltransferase 1 | 0.691256 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.690096 |
| GLRX | glutaredoxin (thioltransferase) | 0.686213 |
| GFM1 | G elongation factor, mitochondrial 1 | 0.684555 |
| FDPS | farnesyl diphosphate synthase | 0.682333 |
| LDHA | lactate dehydrogenase A | 0.680761 |
| AMD1 | adenosylmethionine decarboxylase 1 | 0.680491 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.680298 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.680207 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.678157 |
| THOC6 | THO complex 6 | 0.675691 |
| ENO1 | enolase 1, (alpha) | 0.675544 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.674476 |
| ARF3 | ADP-ribosylation factor 3 | 0.673026 |
| EIF3G | eukaryotic translation initiation factor 3, subunit G | 0.671725 |
| GPATCH4 | G patch domain containing 4 | 0.670623 |
| TIMM10 | translocase of inner mitochondrial membrane 10 homolog (yeast) | 0.668816 |
| AGPAT6 | 1-acylglycerol-3-phosphate O-acyltransferase 6 | 0.668794 |
| WDR43 | WD repeat domain 43 | 0.667825 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.667667 |
| TRIB2 | tribbles pseudokinase 2 | 0.665199 |
| TTC9 | tetratricopeptide repeat domain 9 | 0.664479 |
| RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast) | 0.663881 |
| RRP7A | ribosomal RNA processing 7 homolog A (S. cerevisiae) | 0.66385 |
| SOCS5 | suppressor of cytokine signaling 5 | 0.663293 |
| GXYLT1 | glucoside xylosyltransferase 1 | 0.661336 |
| ODC1 | ornithine decarboxylase 1 | 0.659847 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.656221 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.65292 |
| RFK | riboflavin kinase | 0.651566 |
| RIPK3 | receptor-interacting serine-threonine kinase 3 | 0.650288 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.64839 |
| PES1 | pescadillo ribosomal biogenesis factor 1 | 0.645509 |
| FAM104A | family with sequence similarity 104, member A | 0.644731 |
| ETV3 | ets variant 3 | 0.643272 |
| EBNA1BP2 | EBNA1 binding protein 2 | 0.642934 |
| CSPG4 | chondroitin sulfate proteoglycan 4 | 0.642035 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.638554 |
| FJX1 | four jointed box 1 (Drosophila) | 0.636713 |
| MRPL17 | mitochondrial ribosomal protein L17 | 0.632365 |
| CCDC137 | coiled-coil domain containing 137 | 0.627753 |
| TLK2 | tousled-like kinase 2 | 0.626015 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) | 0.623936 |
| METTL16 | methyltransferase like 16 | 0.621891 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 0.620452 |
| CXCL16 | chemokine (C-X-C motif) ligand 16 | 0.619847 |
| MYO1E | myosin IE | 0.616347 |
| EIF4E2 | eukaryotic translation initiation factor 4E family member 2 | 0.613976 |
| KLF6 | Kruppel-like factor 6 | 0.613605 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.610207 |
| FAM133B | family with sequence similarity 133, member B | 0.609454 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.609363 |
| STAMBPL1 | STAM binding protein-like 1 | 0.60852 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.607394 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | 0.606423 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.603285 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.60273 |
| ENOPH1 | enolase-phosphatase 1 | 0.600253 |
| MRPL19 | mitochondrial ribosomal protein L19 | 0.599704 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.59844 |
| NAV2 | neuron navigator 2 | 0.598152 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.597937 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.597398 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.5964 |
| PROCR | protein C receptor, endothelial | 0.594041 |
| FST | follistatin | 0.592445 |
| HBEGF | heparin-binding EGF-like growth factor | 0.591724 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.58946 |
| NOP9 | NOP9 nucleolar protein | 0.586418 |
| USP36 | ubiquitin specific peptidase 36 | 0.583829 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.583481 |
| CUL2 | cullin 2 | 0.580611 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 | 0.57882 |
| TMEM185B | transmembrane protein 185B | 0.577937 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.577714 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) | 0.574182 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.573525 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 | 0.573453 |
| MPHOSPH6 | M-phase phosphoprotein 6 | 0.572914 |
| EMC6 | ER membrane protein complex subunit 6 | 0.571594 |
| HK2 | hexokinase 2 | 0.569218 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.567201 |
| NUP205 | nucleoporin 205kDa | 0.564609 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.562495 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.561866 |
| ZNHIT2 | zinc finger, HIT-type containing 2 | 0.561714 |
| DNAAF5 | dynein, axonemal, assembly factor 5 | 0.561513 |
| EXOSC2 | exosome component 2 | 0.561501 |
| IER3 | immediate early response 3 | 0.561127 |
| SLBP | stem-loop binding protein | 0.559197 |
| SDC1 | syndecan 1 | 0.559111 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) | 0.558822 |
| VDAC2 | voltage-dependent anion channel 2 | 0.558433 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.555348 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.554647 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.551858 |
| TOP1 | topoisomerase (DNA) I | 0.547774 |
| MICU3 | mitochondrial calcium uptake family, member 3 | 0.547044 |
| ANKRD49 | ankyrin repeat domain 49 | 0.546426 |
| MRPS2 | mitochondrial ribosomal protein S2 | 0.54544 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.544474 |
| ARF6 | ADP-ribosylation factor 6 | 0.54338 |
| ARG1 | arginase 1 | 0.542163 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 | 0.541877 |
| RBM17 | RNA binding motif protein 17 | 0.541836 |
| ACOT9 | acyl-CoA thioesterase 9 | 0.539599 |
| AIMP2 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 | 0.53915 |
| LTV1 | LTV1 ribosome biogenesis factor | 0.53872 |
| OGFRL1 | opioid growth factor receptor-like 1 | 0.538386 |
| THOC1 | THO complex 1 | 0.538381 |
| E2F5 | E2F transcription factor 5, p130-binding | 0.537121 |
| MYBBP1A | MYB binding protein (P160) 1a | 0.535697 |
| KPNB1 | karyopherin (importin) beta 1 | 0.535014 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.533158 |
| SYS1 | Sys1 golgi trafficking protein | 0.531217 |
| ANKRD28 | ankyrin repeat domain 28 | 0.530236 |
| RUVBL1 | RuvB-like AAA ATPase 1 | 0.52582 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZFAND6 | zinc finger, AN1-type domain 6 | -2.84085 |
| XDH | xanthine dehydrogenase | -2.43906 |
| CIR1 | corepressor interacting with RBPJ, 1 | -2.41367 |
| CEP19 | centrosomal protein 19kDa | -2.40369 |
| ETFDH | electron-transferring-flavoprotein dehydrogenase | -2.37993 |
| BOC | BOC cell adhesion associated, oncogene regulated | -2.21145 |
| FAM117B | family with sequence similarity 117, member B | -2.07107 |
| SLMAP | sarcolemma associated protein | -2.01395 |
| MRPS33 | mitochondrial ribosomal protein S33 | -1.86858 |
| FILIP1L | filamin A interacting protein 1-like | -1.85539 |
| DENND4A | DENN/MADD domain containing 4A | -1.80625 |
| RILPL2 | Rab interacting lysosomal protein-like 2 | -1.80004 |
| ZNF579 | zinc finger protein 579 | -1.77427 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | -1.7157 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -1.68461 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | -1.67722 |
| GRHPR | glyoxylate reductase/hydroxypyruvate reductase | -1.67667 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -1.61681 |
| LMO4 | LIM domain only 4 | -1.59674 |
| NGLY1 | N-glycanase 1 | -1.58479 |
| ZFYVE21 | zinc finger, FYVE domain containing 21 | -1.48777 |
| TBCCD1 | TBCC domain containing 1 | -1.48646 |
| COMMD9 | COMM domain containing 9 | -1.46858 |
| FAM63A | family with sequence similarity 63, member A | -1.45648 |
| MXRA8 | matrix-remodelling associated 8 | -1.43194 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | -1.41297 |
| XRCC6BP1 | XRCC6 binding protein 1 | -1.4074 |
| ELMO2 | engulfment and cell motility 2 | -1.40735 |
| COASY | CoA synthase | -1.37855 |
| PHF8 | PHD finger protein 8 | -1.37012 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -1.34726 |
| ACOX3 | acyl-CoA oxidase 3, pristanoyl | -1.33842 |
| H1F0 | H1 histone family, member 0 | -1.33565 |
| TMX2 | thioredoxin-related transmembrane protein 2 | -1.32394 |
| TSPAN3 | tetraspanin 3 | -1.31995 |
| MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) | -1.31483 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -1.30777 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 | -1.29657 |
| RNF26 | ring finger protein 26 | -1.28773 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -1.25863 |
| PARVA | parvin, alpha | -1.25348 |
| FGFR3 | fibroblast growth factor receptor 3 | -1.25154 |
| FZD8 | frizzled class receptor 8 | -1.23958 |
| NONO | non-POU domain containing, octamer-binding | -1.21253 |
| TMEM136 | transmembrane protein 136 | -1.20596 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -1.20277 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -1.20127 |
| EIF4B | eukaryotic translation initiation factor 4B | -1.18446 |
| GLT8D1 | glycosyltransferase 8 domain containing 1 | -1.1834 |
| EVI5 | ecotropic viral integration site 5 | -1.17701 |
| LMCD1 | LIM and cysteine-rich domains 1 | -1.17614 |
| GGCX | gamma-glutamyl carboxylase | -1.17202 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -1.15231 |
| IVD | isovaleryl-CoA dehydrogenase | -1.14804 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | -1.14404 |
| EXOC3 | exocyst complex component 3 | -1.13318 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -1.12471 |
| TNIP1 | TNFAIP3 interacting protein 1 | -1.12289 |
| RBM39 | RNA binding motif protein 39 | -1.11945 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -1.11274 |
| VPS26B | vacuolar protein sorting 26 homolog B (S. pombe) | -1.10752 |
| VCAM1 | vascular cell adhesion molecule 1 | -1.10499 |
| RAB12 | RAB12, member RAS oncogene family | -1.09458 |
| BNC2 | basonuclin 2 | -1.09135 |
| TXNIP | thioredoxin interacting protein | -1.08934 |
| FCHSD2 | FCH and double SH3 domains 2 | -1.0842 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -1.08156 |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 | -1.06788 |
| SH3D19 | SH3 domain containing 19 | -1.03957 |
| ANAPC2 | anaphase promoting complex subunit 2 | -1.03716 |
| DGCR2 | DiGeorge syndrome critical region gene 2 | -1.02489 |
| SKAP2 | src kinase associated phosphoprotein 2 | -1.02482 |
| HDDC3 | HD domain containing 3 | -1.01918 |
| PCNX | pecanex homolog (Drosophila) | -1.0174 |
| CCDC90B | coiled-coil domain containing 90B | -1.00919 |
| MAGED1 | melanoma antigen family D1 | -1.0011 |
| CDO1 | cysteine dioxygenase type 1 | -1.00107 |
| COG6 | component of oligomeric golgi complex 6 | -0.998214 |
| DOLK | dolichol kinase | -0.997565 |
| PON2 | paraoxonase 2 | -0.997057 |
| SLC22A18 | solute carrier family 22, member 18 | -0.99054 |
| NTPCR | nucleoside-triphosphatase, cancer-related | -0.989195 |
| HEXB | hexosaminidase B (beta polypeptide) | -0.986764 |
| FBXL8 | F-box and leucine-rich repeat protein 8 | -0.982129 |
| RBL2 | retinoblastoma-like 2 | -0.981522 |
| INPP5K | inositol polyphosphate-5-phosphatase K | -0.980414 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.977256 |
| TRIM2 | tripartite motif containing 2 | -0.969903 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.962407 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 | -0.960539 |
| USP39 | ubiquitin specific peptidase 39 | -0.959371 |
| ANGPT2 | angiopoietin 2 | -0.956811 |
| SLC35A5 | solute carrier family 35, member A5 | -0.956631 |
| NEK7 | NIMA-related kinase 7 | -0.952365 |
| ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 | -0.946472 |
| RAD21 | RAD21 homolog (S. pombe) | -0.941773 |
| BMP4 | bone morphogenetic protein 4 | -0.937673 |
| ZNF266 | zinc finger protein 266 | -0.935668 |
| SELENBP1 | selenium binding protein 1 | -0.935122 |
| SRI | sorcin | -0.92893 |
| GLTSCR2 | glioma tumor suppressor candidate region gene 2 | -0.927538 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 | -0.924501 |
| CCNG2 | cyclin G2 | -0.921812 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 | -0.917411 |
| TCF4 | transcription factor 4 | -0.909144 |
| ATP6V1E1 | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | -0.90733 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | -0.902886 |
| SUMF2 | sulfatase modifying factor 2 | -0.900781 |
| MKRN2 | makorin ring finger protein 2 | -0.89611 |
| ISCU | iron-sulfur cluster assembly enzyme | -0.893612 |
| JKAMP | JNK1/MAPK8-associated membrane protein | -0.890015 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.889388 |
| CCNG1 | cyclin G1 | -0.883182 |
| CEP120 | centrosomal protein 120kDa | -0.882833 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.880688 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.880468 |
| RAB30 | RAB30, member RAS oncogene family | -0.879412 |
| CNTROB | centrobin, centrosomal BRCA2 interacting protein | -0.87338 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.873359 |
| TECR | trans-2,3-enoyl-CoA reductase | -0.867966 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.860232 |
| ESD | esterase D | -0.859248 |
| SERINC3 | serine incorporator 3 | -0.855259 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 | -0.84946 |
| LRRC57 | leucine rich repeat containing 57 | -0.849112 |
| POGLUT1 | protein O-glucosyltransferase 1 | -0.847591 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.830944 |
| EHBP1 | EH domain binding protein 1 | -0.828454 |
| KIAA0430 | KIAA0430 | -0.825885 |
| TTC13 | tetratricopeptide repeat domain 13 | -0.825607 |
| COPG1 | coatomer protein complex, subunit gamma 1 | -0.82353 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.820855 |
| RAB2B | RAB2B, member RAS oncogene family | -0.816456 |
| ADD3 | adducin 3 (gamma) | -0.815836 |
| EDN1 | endothelin 1 | -0.815684 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | -0.808932 |
| MXI1 | MAX interactor 1, dimerization protein | -0.806922 |
| LPL | lipoprotein lipase | -0.805466 |
| AGTR1 | angiotensin II receptor, type 1 | -0.804065 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.80406 |
| FAM198B | family with sequence similarity 198, member B | -0.801887 |
| CD47 | CD47 molecule | -0.798398 |
| SYNJ2BP | synaptojanin 2 binding protein | -0.797477 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 | -0.796829 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.795243 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | -0.792851 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | -0.791331 |
| HES6 | hes family bHLH transcription factor 6 | -0.790871 |
| ACAD11 | acyl-CoA dehydrogenase family, member 11 | -0.790256 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 | -0.789881 |
| WWC2 | WW and C2 domain containing 2 | -0.789265 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.787783 |
| RRM1 | ribonucleotide reductase M1 | -0.787242 |
| FBXL4 | F-box and leucine-rich repeat protein 4 | -0.783814 |
| DIRC2 | disrupted in renal carcinoma 2 | -0.781422 |
| CDK19 | cyclin-dependent kinase 19 | -0.781034 |
| SMAD1 | SMAD family member 1 | -0.777017 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -0.773382 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.770661 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | -0.766665 |
| MARCH8 | membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase | -0.765336 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | -0.765271 |
| INO80B | INO80 complex subunit B | -0.763978 |
| RMI1 | RecQ mediated genome instability 1 | -0.760058 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A | -0.758438 |
| SAMD14 | sterile alpha motif domain containing 14 | -0.757281 |
| POLE4 | polymerase (DNA-directed), epsilon 4, accessory subunit | -0.754664 |
| CNPY2 | canopy FGF signaling regulator 2 | -0.751845 |
| PPOX | protoporphyrinogen oxidase | -0.751416 |
| LEPROT | leptin receptor overlapping transcript | -0.750919 |
| EBF1 | early B-cell factor 1 | -0.742509 |
| NRP1 | neuropilin 1 | -0.740304 |
| LATS2 | large tumor suppressor kinase 2 | -0.738517 |
| TMEM45A | transmembrane protein 45A | -0.735935 |
| MSL3 | male-specific lethal 3 homolog (Drosophila) | -0.734681 |
| SCARA5 | scavenger receptor class A, member 5 | -0.734574 |
| RNF14 | ring finger protein 14 | -0.734389 |
| SMIM20 | small integral membrane protein 20 | -0.733167 |
| VLDLR | very low density lipoprotein receptor | -0.732329 |
| XPO1 | exportin 1 | -0.72678 |
| APOO | apolipoprotein O | -0.726773 |
| HMGB2 | high mobility group box 2 | -0.726572 |
| RAB13 | RAB13, member RAS oncogene family | -0.723743 |
| IFT172 | intraflagellar transport 172 | -0.720268 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | -0.715318 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.71457 |
| FAM3A | family with sequence similarity 3, member A | -0.714215 |
| TPP1 | tripeptidyl peptidase I | -0.710535 |
| CLIC3 | chloride intracellular channel 3 | -0.710346 |
| TSPAN6 | tetraspanin 6 | -0.709834 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.709237 |
| SNX1 | sorting nexin 1 | -0.708579 |
| KIF22 | kinesin family member 22 | -0.707776 |
| METTL20 | methyltransferase like 20 | -0.704989 |
| SERTAD4 | SERTA domain containing 4 | -0.704213 |
| PI4KB | phosphatidylinositol 4-kinase, catalytic, beta | -0.70279 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.701741 |
| VPS25 | vacuolar protein sorting 25 homolog (S. cerevisiae) | -0.699574 |
| RASSF7 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 | -0.698204 |
| NCAPH2 | non-SMC condensin II complex, subunit H2 | -0.697712 |
| BRE | brain and reproductive organ-expressed (TNFRSF1A modulator) | -0.695708 |
| PHYH | phytanoyl-CoA 2-hydroxylase | -0.69535 |
| CYB561D2 | cytochrome b561 family, member D2 | -0.693772 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.692796 |
| KLHL24 | kelch-like family member 24 | -0.692691 |
| OXR1 | oxidation resistance 1 | -0.689245 |
| NTNG1 | netrin G1 | -0.688597 |
| CMTM3 | CKLF-like MARVEL transmembrane domain containing 3 | -0.688562 |
| LONP2 | lon peptidase 2, peroxisomal | -0.684931 |
| TNRC6C | trinucleotide repeat containing 6C | -0.682527 |
| CNNM3 | cyclin and CBS domain divalent metal cation transport mediator 3 | -0.680676 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.677464 |
| PMVK | phosphomevalonate kinase | -0.675643 |
| TSPYL4 | TSPY-like 4 | -0.673821 |
| KDELC2 | KDEL (Lys-Asp-Glu-Leu) containing 2 | -0.673028 |
| CCS | copper chaperone for superoxide dismutase | -0.672473 |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain | -0.67195 |
| MKRN1 | makorin ring finger protein 1 | -0.670423 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.664184 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.660183 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) | -0.657397 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | -0.656805 |
| COG1 | component of oligomeric golgi complex 1 | -0.656316 |
| MFSD1 | major facilitator superfamily domain containing 1 | -0.655967 |
| TC2N | tandem C2 domains, nuclear | -0.655696 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.654705 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.654037 |
| AGA | aspartylglucosaminidase | -0.654002 |
| NICN1 | nicolin 1 | -0.653097 |
| UBLCP1 | ubiquitin-like domain containing CTD phosphatase 1 | -0.650022 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa | -0.648476 |
| PLD2 | phospholipase D2 | -0.648339 |
| TMEM88 | transmembrane protein 88 | -0.648264 |
| IRF9 | interferon regulatory factor 9 | -0.647683 |
| MOB2 | MOB kinase activator 2 | -0.647352 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | -0.646386 |
| TTC23 | tetratricopeptide repeat domain 23 | -0.646219 |
| GRB14 | growth factor receptor-bound protein 14 | -0.64609 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal | -0.645584 |
| MAT2B | methionine adenosyltransferase II, beta | -0.644974 |
| PROSER1 | proline and serine rich 1 | -0.643766 |
| TNRC6A | trinucleotide repeat containing 6A | -0.640032 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.637192 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.634585 |
| LXN | latexin | -0.634093 |
| GALK2 | galactokinase 2 | -0.63407 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.631483 |
| GAK | cyclin G associated kinase | -0.630125 |
| FAHD2B | fumarylacetoacetate hydrolase domain containing 2B | -0.630039 |
| CYTL1 | cytokine-like 1 | -0.628373 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 | -0.628353 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | -0.627689 |
| TXNDC15 | thioredoxin domain containing 15 | -0.626912 |
| RNPC3 | RNA-binding region (RNP1, RRM) containing 3 | -0.626707 |
| L3HYPDH | L-3-hydroxyproline dehydratase (trans-) | -0.626447 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.625332 |
| BBX | bobby sox homolog (Drosophila) | -0.623807 |
| PIK3R4 | phosphoinositide-3-kinase, regulatory subunit 4 | -0.623515 |
| FANCL | Fanconi anemia, complementation group L | -0.622655 |
| CHFR | checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase | -0.621818 |
| KCTD2 | potassium channel tetramerization domain containing 2 | -0.621435 |
| TRIM32 | tripartite motif containing 32 | -0.62001 |
| TBC1D14 | TBC1 domain family, member 14 | -0.618873 |
| SKIV2L2 | superkiller viralicidic activity 2-like 2 (S. cerevisiae) | -0.616683 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.616599 |
| RECQL | RecQ helicase-like | -0.615465 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.614818 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | -0.614329 |
| PTPRA | protein tyrosine phosphatase, receptor type, A | -0.613479 |
| ERCC5 | excision repair cross-complementation group 5 | -0.611966 |
| PNKD | paroxysmal nonkinesigenic dyskinesia | -0.61152 |
| TMEM159 | transmembrane protein 159 | -0.611152 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.609215 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.609072 |
| EMC2 | ER membrane protein complex subunit 2 | -0.607828 |
| NDUFB4 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa | -0.602608 |
| ANXA4 | annexin A4 | -0.601009 |
| CALHM2 | calcium homeostasis modulator 2 | -0.600642 |
| TMEM204 | transmembrane protein 204 | -0.598873 |
| LDHB | lactate dehydrogenase B | -0.596115 |
| POP5 | processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) | -0.594989 |
| OSTF1 | osteoclast stimulating factor 1 | -0.594176 |
| RCAN2 | regulator of calcineurin 2 | -0.593908 |
| RASGRP3 | RAS guanyl releasing protein 3 (calcium and DAG-regulated) | -0.593481 |
| ZNF22 | zinc finger protein 22 | -0.58962 |
| JAK1 | Janus kinase 1 | -0.58877 |
| TMEM218 | transmembrane protein 218 | -0.586002 |
| CHMP5 | charged multivesicular body protein 5 | -0.58572 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.585358 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -0.584888 |
| MPPE1 | metallophosphoesterase 1 | -0.584384 |
| AMACR | alpha-methylacyl-CoA racemase | -0.583444 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.581214 |
| SF3B5 | splicing factor 3b, subunit 5, 10kDa | -0.580497 |
| AFAP1L2 | actin filament associated protein 1-like 2 | -0.580485 |
| SARAF | store-operated calcium entry-associated regulatory factor | -0.580336 |
| TXNDC16 | thioredoxin domain containing 16 | -0.577147 |
| TSC22D3 | TSC22 domain family, member 3 | -0.576528 |
| RTF1 | Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | -0.57643 |
| CTDSP2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 | -0.57538 |
