EGR1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description early growth response 1|The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014] (NCBI Entrez Gene Database, 1958)
External Link https://ncbi.nlm.nih.gov/gene/1958
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Genes

498 genes differentially expressed following the EGR1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00925335
PLK2 polo-like kinase 2 0.00879013
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00860699
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00835406
POSTN periostin, osteoblast specific factor 0.00776663
RGS4 regulator of G-protein signaling 4 0.00731359
TMEM176B transmembrane protein 176B 0.00730079
HSPA2 heat shock 70kDa protein 2 0.00713384
HSPA1A heat shock 70kDa protein 1A 0.00710074
BAMBI BMP and activin membrane-bound inhibitor 0.00707162
AREG amphiregulin 0.00705987
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.0069162
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00677278
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00676245
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00657147
PLIN2 perilipin 2 0.00646298
KRT19 keratin 19, type I 0.00643891
DLK1 delta-like 1 homolog (Drosophila) 0.00636928
MEG3 maternally expressed 3 (non-protein coding) 0.00633153
C1QB complement component 1, q subcomponent, B chain 0.00613869
TTC39A tetratricopeptide repeat domain 39A 0.00602144
NUTF2 nuclear transport factor 2 0.00600133
CD163 CD163 molecule 0.00595909
RRAGA Ras-related GTP binding A 0.00590064
CPM carboxypeptidase M 0.00589845
C1QA complement component 1, q subcomponent, A chain 0.00586294
CA12 carbonic anhydrase XII 0.00580247
DST dystonin 0.00578591
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00576307
RND3 Rho family GTPase 3 0.00571585
NEFM neurofilament, medium polypeptide 0.0056778
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 0.00561902
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.005611
HOXB6 homeobox B6 0.00558561
TAGLN transgelin 0.00558375
LTF lactotransferrin 0.00557174
NUPR1 nuclear protein, transcriptional regulator, 1 0.00554366
HSPH1 heat shock 105kDa/110kDa protein 1 0.00542365
VSIG4 V-set and immunoglobulin domain containing 4 0.00539475
BTG2 BTG family, member 2 0.0053477
LGALS3 lectin, galactoside-binding, soluble, 3 0.00534336
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00531733
MPPED2 metallophosphoesterase domain containing 2 0.00528044
BCAS1 breast carcinoma amplified sequence 1 0.00522819
ZNF395 zinc finger protein 395 0.00521103
TPPP3 tubulin polymerization-promoting protein family member 3 0.00514882
CHI3L2 chitinase 3-like 2 0.00508775
GLUL glutamate-ammonia ligase 0.00508163
VEGFA vascular endothelial growth factor A 0.00505329
SNAP25 synaptosomal-associated protein, 25kDa 0.00502985
CAPN3 calpain 3, (p94) 0.00502869
TCTA T-cell leukemia translocation altered 0.00498908
SLC31A2 solute carrier family 31 (copper transporter), member 2 0.00496389
HNMT histamine N-methyltransferase 0.00496147
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00495544
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00493035
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.00492214
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.00488395
FAM46C family with sequence similarity 46, member C 0.00483285
BEX1 brain expressed, X-linked 1 0.0048304
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00482813
RFTN1 raftlin, lipid raft linker 1 0.00481423
LUM lumican 0.00480796
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.00479881
ASPN asporin 0.00476258
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00474758
CXCL13 chemokine (C-X-C motif) ligand 13 0.00473999
MTUS1 microtubule associated tumor suppressor 1 0.00468165
EPCAM epithelial cell adhesion molecule 0.00467248
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.00465864
ELOVL1 ELOVL fatty acid elongase 1 0.00463636
SNAI2 snail family zinc finger 2 0.00459143
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00458734
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00456635
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 0.00455425
COQ8A coenzyme Q8A 0.00455417
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00452907
DNM1L dynamin 1-like 0.00452879
DCN decorin 0.00448505
RBM34 RNA binding motif protein 34 0.00446675
GATA6 GATA binding protein 6 0.0044577
IFI6 interferon, alpha-inducible protein 6 0.00445647
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.00444859
CCL20 chemokine (C-C motif) ligand 20 0.00443049
VAV3 vav 3 guanine nucleotide exchange factor 0.00441309
SMS spermine synthase 0.00440848
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.0044069
ZNF652 zinc finger protein 652 0.00438413
MFAP3L microfibrillar-associated protein 3-like 0.00437998
TSPAN8 tetraspanin 8 0.00434408
WIF1 WNT inhibitory factor 1 0.00430975
ADGRF5 adhesion G protein-coupled receptor F5 0.00430966
HIST1H2BD histone cluster 1, H2bd 0.00428646
MAPK13 mitogen-activated protein kinase 13 0.0042716
ZNF91 zinc finger protein 91 0.00425794
TBX2 T-box 2 0.00425464
CNTN1 contactin 1 0.00425107
FRMD4B FERM domain containing 4B 0.0042491
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.00422523
HSBP1 heat shock factor binding protein 1 0.00422423
LAMB1 laminin, beta 1 0.00421555
ZBTB38 zinc finger and BTB domain containing 38 0.00420905
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00420804
CTSB cathepsin B 0.00420336
SCGB2A1 secretoglobin, family 2A, member 1 0.00418838
GATA3 GATA binding protein 3 0.00417612
MGP matrix Gla protein 0.00417302
PUDP pseudouridine 5'-phosphatase 0.00415033
KIF1A kinesin family member 1A 0.00414675
FBN2 fibrillin 2 0.00413835
CAPG capping protein (actin filament), gelsolin-like 0.0041363
CD14 CD14 molecule 0.00409268
CTTN cortactin 0.00408994
CGRRF1 cell growth regulator with ring finger domain 1 0.00408552
FXYD3 FXYD domain containing ion transport regulator 3 0.00408353
PLXNC1 plexin C1 0.00406715
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00406165
CHGB chromogranin B 0.00405822
CYBB cytochrome b-245, beta polypeptide 0.00405624
STMN2 stathmin 2 0.00404655
CKS2 CDC28 protein kinase regulatory subunit 2 0.00404159
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.00402532
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00402033
KRT18 keratin 18, type I 0.00399938
SLN sarcolipin 0.00399883
PRNP prion protein 0.00399093
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00398712
CD44 CD44 molecule (Indian blood group) 0.00397495
ZFP36 ZFP36 ring finger protein 0.00397362
RCAN2 regulator of calcineurin 2 0.00396913
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00395919
C3AR1 complement component 3a receptor 1 0.00395054
GPX2 glutathione peroxidase 2 0.00394874
TMEM176A transmembrane protein 176A 0.00394223
GLIPR1 GLI pathogenesis-related 1 0.00390902
SOX9 SRY (sex determining region Y)-box 9 0.0038975
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.00389401
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.00388299
THBS1 thrombospondin 1 0.00388094
MET MET proto-oncogene, receptor tyrosine kinase 0.0038787
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00386509
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0038549
EFHD1 EF-hand domain family, member D1 0.0038539
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 0.00385215
KCTD12 potassium channel tetramerization domain containing 12 0.00385118
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 0.00385008
FTH1 ferritin, heavy polypeptide 1 0.00384084
FILIP1L filamin A interacting protein 1-like 0.00384024
ARHGAP29 Rho GTPase activating protein 29 0.00381375
MORC4 MORC family CW-type zinc finger 4 0.00381102
NEFH neurofilament, heavy polypeptide 0.00381013
ADCY1 adenylate cyclase 1 (brain) 0.00381008
HSPB8 heat shock 22kDa protein 8 0.00378788
SPARCL1 SPARC-like 1 (hevin) 0.00377637
A2M alpha-2-macroglobulin 0.00376724
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.0037581
RTN2 reticulon 2 0.00375213
CACYBP calcyclin binding protein 0.00374895
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00374067
SFRP4 secreted frizzled-related protein 4 0.00372732
GPR137B G protein-coupled receptor 137B 0.00371353
IFRD1 interferon-related developmental regulator 1 0.00371296
SMAD7 SMAD family member 7 0.00371201
RGS1 regulator of G-protein signaling 1 0.00370566
KRT20 keratin 20, type I 0.00369577
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00368235
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.00368159
ZDHHC7 zinc finger, DHHC-type containing 7 0.00367653
RGS5 regulator of G-protein signaling 5 0.00367309
CLIC3 chloride intracellular channel 3 0.00366947
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00366897
COL5A2 collagen, type V, alpha 2 0.00366881
METRN meteorin, glial cell differentiation regulator 0.00365752
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00365637
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.00365133
GCH1 GTP cyclohydrolase 1 0.00364865
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00361847
TIGAR TP53 induced glycolysis regulatory phosphatase 0.00361676
CPB1 carboxypeptidase B1 (tissue) 0.00360676
IRS1 insulin receptor substrate 1 0.00359508
TPD52 tumor protein D52 0.00358335
SHTN1 shootin 1 0.00358327
ACP5 acid phosphatase 5, tartrate resistant 0.00356661
OLFM1 olfactomedin 1 0.00356414
FAIM2 Fas apoptotic inhibitory molecule 2 0.00356157
FRS2 fibroblast growth factor receptor substrate 2 0.00355991
MMP1 matrix metallopeptidase 1 0.00355801
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.00355373
FKBP14 FK506 binding protein 14, 22 kDa 0.00353613
SIDT2 SID1 transmembrane family, member 2 0.00353061
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00352896
STC2 stanniocalcin 2 0.00352288
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00351791
RAI14 retinoic acid induced 14 0.00349865
PIEZO2 piezo-type mechanosensitive ion channel component 2 0.00349424
CSRP1 cysteine and glycine-rich protein 1 0.00349258
RNASET2 ribonuclease T2 0.00349004
ADAP2 ArfGAP with dual PH domains 2 0.00348715
NEU1 sialidase 1 (lysosomal sialidase) 0.00348471
NAV3 neuron navigator 3 0.00347803
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.00347011
SEPTIN4 septin 4 0.00346529
LPAR1 lysophosphatidic acid receptor 1 0.00345564
MAP1B microtubule-associated protein 1B 0.00342584
PDK3 pyruvate dehydrogenase kinase, isozyme 3 0.00342266
S100A4 S100 calcium binding protein A4 0.0034215
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.00341529
SYNE1 spectrin repeat containing, nuclear envelope 1 0.0034086
DKFZP586I1420 uncharacterized protein DKFZp586I1420 0.00340784
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 0.00340104
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.00339649
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.00338921
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.00338191
SELENOT selenoprotein T 0.00337206
IER5 immediate early response 5 0.00336986
LXN latexin 0.00336955
AVIL advillin 0.00336863
PCYOX1 prenylcysteine oxidase 1 0.0033586
TMBIM1 transmembrane BAX inhibitor motif containing 1 0.00335253
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.00335139
CDV3 CDV3 homolog (mouse) 0.00334831
SAMD4A sterile alpha motif domain containing 4A 0.00334256
AMIGO2 adhesion molecule with Ig-like domain 2 0.0033405
ELF5 E74-like factor 5 (ets domain transcription factor) 0.00333499
EDNRA endothelin receptor type A 0.00332961
MAG myelin associated glycoprotein 0.0033269
PLPP2 phospholipid phosphatase 2 0.00332567
MBL2 mannose-binding lectin (protein C) 2, soluble 0.00332379
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.00331919
PALLD palladin, cytoskeletal associated protein 0.0033131
C3ORF52 chromosome 3 open reading frame 52 0.00331092
KLF4 Kruppel-like factor 4 (gut) 0.00331039
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00330269
PDZD8 PDZ domain containing 8 0.00329735
PMP2 peripheral myelin protein 2 0.00329501
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 0.00329358
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0032927
ANKRD11 ankyrin repeat domain 11 0.00328595
PLXNA2 plexin A2 0.00327557
SUCO SUN domain containing ossification factor 0.0032685
COG7 component of oligomeric golgi complex 7 0.00326658
H1-2 H1.2 linker histone, cluster member 0.00326051
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 0.00325538
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00325426
RTCA RNA 3'-terminal phosphate cyclase 0.00324947
PIR pirin (iron-binding nuclear protein) 0.00324149
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00323148
COA3 cytochrome c oxidase assembly factor 3 0.00322806
CTSH cathepsin H 0.00322321

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -0.01165
TUBB6 tubulin, beta 6 class V -0.0114455
LCN2 lipocalin 2 -0.0109918
S100A9 S100 calcium binding protein A9 -0.00996708
FST follistatin -0.00752246
PDZK1IP1 PDZK1 interacting protein 1 -0.00707504
S100A2 S100 calcium binding protein A2 -0.00691369
PPL periplakin -0.0069007
FHL1 four and a half LIM domains 1 -0.00680325
KIF20A kinesin family member 20A -0.00646918
S100A7 S100 calcium binding protein A7 -0.00643509
CLC Charcot-Leyden crystal galectin -0.00636482
CXADR coxsackie virus and adenovirus receptor -0.0062499
NMU neuromedin U -0.00620115
AK4 adenylate kinase 4 -0.00617227
KRT1 keratin 1, type II -0.00613374
TM4SF1 transmembrane 4 L six family member 1 -0.00613078
NUSAP1 nucleolar and spindle associated protein 1 -0.00609315
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00598036
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00598014
JCHAIN joining chain of multimeric IgA and IgM -0.00592792
DHCR24 24-dehydrocholesterol reductase -0.00592522
S100A12 S100 calcium binding protein A12 -0.00591208
AQP3 aquaporin 3 (Gill blood group) -0.00585506
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -0.00581796
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00576131
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.00567225
SDC2 syndecan 2 -0.00564879
HMG20B high mobility group 20B -0.00564065
SPINK5 serine peptidase inhibitor, Kazal type 5 -0.00559323
CCNF cyclin F -0.00557111
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.0055466
TPSAB1 tryptase alpha/beta 1 -0.00546468
SPON1 spondin 1, extracellular matrix protein -0.00542685
DBN1 drebrin 1 -0.00541109
KRT6A keratin 6A, type II -0.00540064
CALML3 calmodulin-like 3 -0.00537063
SOCS2 suppressor of cytokine signaling 2 -0.0053145
PXDN peroxidasin -0.00529516
LMNB1 lamin B1 -0.00520824
BAX BCL2-associated X protein -0.00516337
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00514996
GARS1 glycyl-tRNA synthetase 1 -0.00511764
SPTSSA serine palmitoyltransferase, small subunit A -0.00510664
TMPRSS4 transmembrane protease, serine 4 -0.00508713
TNC tenascin C -0.00506437
RNF130 ring finger protein 130 -0.00503381
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00503275
TMED9 transmembrane emp24 protein transport domain containing 9 -0.00500236
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -0.0050001
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -0.00499636
HMMR hyaluronan-mediated motility receptor (RHAMM) -0.00497539
TMSB15A thymosin beta 15a -0.00493173
RIPK4 receptor-interacting serine-threonine kinase 4 -0.00491383
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.00485814
PDLIM4 PDZ and LIM domain 4 -0.00483998
SPRR1B small proline-rich protein 1B -0.00483655
TLE4 transducin-like enhancer of split 4 -0.00480811
DCK deoxycytidine kinase -0.00476878
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00475966
ACP3 acid phosphatase 3 -0.00475555
ORC1 origin recognition complex, subunit 1 -0.00475411
LY75 lymphocyte antigen 75 -0.00472737
DUOX2 dual oxidase 2 -0.00472159
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00467124
KRT6B keratin 6B, type II -0.00467117
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.00461393
ASS1 argininosuccinate synthase 1 -0.00457752
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00457284
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.00451972
TCF4 transcription factor 4 -0.00450203
ELANE elastase, neutrophil expressed -0.00449823
AZU1 azurocidin 1 -0.00448045
RNPS1 RNA binding protein S1, serine-rich domain -0.00444058
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00439938
KLK10 kallikrein-related peptidase 10 -0.00439676
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.00438995
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00438283
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.00437972
CLTB clathrin, light chain B -0.00437845
CHRDL1 chordin-like 1 -0.00433435
YBX3 Y box binding protein 3 -0.00432626
KLK8 kallikrein-related peptidase 8 -0.0043262
SSBP3 single stranded DNA binding protein 3 -0.00431932
KRT13 keratin 13, type I -0.00431594
CBS cystathionine-beta-synthase -0.00428963
LMAN2 lectin, mannose-binding 2 -0.00428225
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00426078
CRIP2 cysteine-rich protein 2 -0.00425131
KLK7 kallikrein-related peptidase 7 -0.00423659
TNIP1 TNFAIP3 interacting protein 1 -0.00420659
GREM1 gremlin 1, DAN family BMP antagonist -0.00420156
RAB13 RAB13, member RAS oncogene family -0.00418528
H1-0 H1.0 linker histone -0.00418049
CYB5A cytochrome b5 type A (microsomal) -0.00416828
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0041519
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.0041385
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00413334
HIGD2A HIG1 hypoxia inducible domain family, member 2A -0.00411888
CXCL6 chemokine (C-X-C motif) ligand 6 -0.00410116
DPYSL3 dihydropyrimidinase-like 3 -0.00406076
C1ORF115 chromosome 1 open reading frame 115 -0.00405107
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00402561
GSTZ1 glutathione S-transferase zeta 1 -0.00401558
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00400921
HSP90B2P heat shock protein 90kDa beta (Grp94), member 2, pseudogene -0.00400671
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00400106
RAD51AP1 RAD51 associated protein 1 -0.00397599
PRTN3 proteinase 3 -0.00397443
LY6D lymphocyte antigen 6 complex, locus D -0.00397137
CST6 cystatin E/M -0.00396711
NDFIP1 Nedd4 family interacting protein 1 -0.0039529
HLTF helicase-like transcription factor -0.00394752
FASN fatty acid synthase -0.00393736
OLFM4 olfactomedin 4 -0.00392707
BTG3 BTG family, member 3 -0.00391818
FADS1 fatty acid desaturase 1 -0.00389082
KLK11 kallikrein-related peptidase 11 -0.00388074
IFI44 interferon-induced protein 44 -0.00386942
RBPMS RNA binding protein with multiple splicing -0.00385478
FAM117A family with sequence similarity 117, member A -0.00385168
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00384696
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00384542
FGFBP1 fibroblast growth factor binding protein 1 -0.00384086
CHEK1 checkpoint kinase 1 -0.00380786
CEP57 centrosomal protein 57kDa -0.00380554
FKBP11 FK506 binding protein 11, 19 kDa -0.00380247
U2AF1 U2 small nuclear RNA auxiliary factor 1 -0.00379121
PROM1 prominin 1 -0.00379111
LEPR leptin receptor -0.00378858
FABP6 fatty acid binding protein 6, ileal -0.00377688
TLCD3A TLC domain containing 3A -0.00377514
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.00377084
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.00376821
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -0.00376193
TYRP1 tyrosinase-related protein 1 -0.00375878
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00374999
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -0.00374059
AKAP8 A kinase (PRKA) anchor protein 8 -0.00373989
MAT2B methionine adenosyltransferase II, beta -0.0037297
CNOT8 CCR4-NOT transcription complex, subunit 8 -0.00371222
DIAPH1 diaphanous-related formin 1 -0.00370847
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00370018
BID BH3 interacting domain death agonist -0.00369129
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -0.00369095
PER3 period circadian clock 3 -0.00368507
CD200 CD200 molecule -0.0036846
TM4SF20 transmembrane 4 L six family member 20 -0.00368298
CLINT1 clathrin interactor 1 -0.00367745
ADAM10 ADAM metallopeptidase domain 10 -0.00367342
CD36 CD36 molecule (thrombospondin receptor) -0.00367205
RBM8A RNA binding motif protein 8A -0.00367031
MST1 macrophage stimulating 1 -0.00366708
NHP2 NHP2 ribonucleoprotein -0.00365974
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00365578
CANX calnexin -0.00364894
MME membrane metallo-endopeptidase -0.00364226
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.00364045
SPRR1A small proline-rich protein 1A -0.0036369
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 -0.00362899
IL1RN interleukin 1 receptor antagonist -0.00362424
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 -0.00361697
KRT15 keratin 15, type I -0.00361606
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00360584
EAPP E2F-associated phosphoprotein -0.00360488
DUSP22 dual specificity phosphatase 22 -0.00360336
CPA3 carboxypeptidase A3 (mast cell) -0.00359451
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -0.00359243
WDTC1 WD and tetratricopeptide repeats 1 -0.00358764
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00358297
EMP2 epithelial membrane protein 2 -0.00358178
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00357661
KLK5 kallikrein-related peptidase 5 -0.00357371
PHB2 prohibitin 2 -0.00356511
NMT2 N-myristoyltransferase 2 -0.00356271
HLA-C major histocompatibility complex, class I, C -0.00355911
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00355547
KRT5 keratin 5, type II -0.00355059
HYOU1 hypoxia up-regulated 1 -0.00354595
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -0.00354228
CIT citron rho-interacting serine/threonine kinase -0.00353323
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -0.00352985
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.0035277
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.00352431
BASP1 brain abundant, membrane attached signal protein 1 -0.00352131
MMRN1 multimerin 1 -0.00351673
CAMP cathelicidin antimicrobial peptide -0.00351272
SLIT1 slit homolog 1 (Drosophila) -0.00351094
SSBP2 single-stranded DNA binding protein 2 -0.00351015
LINC00623 long intergenic non-protein coding RNA 623 -0.00349835
BAG1 BCL2-associated athanogene -0.003463
IRAK3 interleukin-1 receptor-associated kinase 3 -0.00345877
MPO myeloperoxidase -0.00345583
PI3 peptidase inhibitor 3, skin-derived -0.00345472
GPC4 glypican 4 -0.00344672
EPHB6 EPH receptor B6 -0.00343641
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B -0.00343445
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -0.0034272
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.0034255
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -0.00342092
NXN nucleoredoxin -0.00341572
FBXW11 F-box and WD repeat domain containing 11 -0.00341437
SC5D sterol-C5-desaturase -0.00340132
ASF1B anti-silencing function 1B histone chaperone -0.00339543
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00338392
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -0.00338353
FAF2 Fas associated factor family member 2 -0.00337068
NRGN neurogranin (protein kinase C substrate, RC3) -0.00337026
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -0.0033682
PSIP1 PC4 and SFRS1 interacting protein 1 -0.00336454
CSTA cystatin A (stefin A) -0.00335428
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.00334758
CCDC47 coiled-coil domain containing 47 -0.0033429
LY6E lymphocyte antigen 6 complex, locus E -0.00334098
COL7A1 collagen, type VII, alpha 1 -0.00333741
RCAN1 regulator of calcineurin 1 -0.00332934
TMEM45A transmembrane protein 45A -0.0033277
NFE2L2 nuclear factor, erythroid 2-like 2 -0.00332414
ECI1 enoyl-CoA delta isomerase 1 -0.00332089
MICALL1 MICAL-like 1 -0.0033118
MSMO1 methylsterol monooxygenase 1 -0.00330411
NOP16 NOP16 nucleolar protein -0.0033026
CDC23 cell division cycle 23 -0.00329969
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 -0.00328999
APOA1 apolipoprotein A-I -0.00328881
ETF1 eukaryotic translation termination factor 1 -0.00328039
RRM2 ribonucleotide reductase M2 -0.00327428
MNDA myeloid cell nuclear differentiation antigen -0.00326779
CD8A CD8a molecule -0.00326576
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0032582
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -0.00325556
RPS14P3 ribosomal protein S14 pseudogene 3 -0.00325146
HDC histidine decarboxylase -0.0032504
PLK1 polo-like kinase 1 -0.00324102
WBP5 WW domain binding protein 5 -0.00323785
SHB Src homology 2 domain containing adaptor protein B -0.00323548
EIF3K eukaryotic translation initiation factor 3, subunit K -0.00322945
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -0.00322216
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.00321821
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -0.00321755
DSG1 desmoglein 1 -0.003217
ACP6 acid phosphatase 6, lysophosphatidic -0.00321542
BRD4 bromodomain containing 4 -0.00321471
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.0032135
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -0.00321312
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -0.00320881
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -0.0032061
ACSL4 acyl-CoA synthetase long-chain family member 4 -0.00320573
LOR loricrin -0.00320513