EGR1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description early growth response 1|The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014] (NCBI Entrez Gene Database, 1958)
External Link http://www.ncbi.nlm.nih.gov/gene/1958
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Genes

34 interacting proteins for EGR1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CREBBP CREB binding protein
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
ELK1 ELK1, member of ETS oncogene family
EP300 E1A binding protein p300
ERBB3 erb-b2 receptor tyrosine kinase 3
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GSK3B glycogen synthase kinase 3 beta
IL1B interleukin 1, beta
JUN jun proto-oncogene
LEF1 lymphoid enhancer-binding factor 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
PFDN5 prefoldin subunit 5
PITX1 paired-like homeodomain 1
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PTEN phosphatase and tensin homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SNAI1 snail family zinc finger 1
SP1 Sp1 transcription factor
SRA1 steroid receptor RNA activator 1
SREBF2 sterol regulatory element binding transcription factor 2
SUMO1 small ubiquitin-like modifier 1
TBX2 T-box 2
TCF4 transcription factor 4
TP53 tumor protein p53
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WT1 Wilms tumor 1