EI24 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description etoposide induced 2.4|This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014] (NCBI Entrez Gene Database, 9538)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_EI24
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Genes

142 co-expressed genes for EI24 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AARS alanyl-tRNA synthetase
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ACTL6A actin-like 6A
AFG3L2 AFG3-like AAA ATPase 2
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ALG3 ALG3, alpha-1,3- mannosyltransferase
ALG8 ALG8, alpha-1,3-glucosyltransferase
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
ATXN10 ataxin 10
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCAP31 B-cell receptor-associated protein 31
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB3 BUB3 mitotic checkpoint protein
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CCNB1 cyclin B1
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
COQ9 coenzyme Q9
CS citrate synthase
CSNK2B casein kinase 2, beta polypeptide
CYCS cytochrome c, somatic
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
DEXI Dexi homolog (mouse)
DGUOK deoxyguanosine kinase
DKC1 dyskeratosis congenita 1, dyskerin
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
DOCK3 dedicator of cytokinesis 3
DYNLL1 dynein, light chain, LC8-type 1
EI24 etoposide induced 2.4
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EPRS glutamyl-prolyl-tRNA synthetase
ESD esterase D
F8A1 coagulation factor VIII-associated 1
FAM120A family with sequence similarity 120A
FH fumarate hydratase
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GANAB glucosidase, alpha; neutral AB
GARS glycyl-tRNA synthetase
GLB1 galactosidase, beta 1
GLO1 glyoxalase I
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNG5 guanine nucleotide binding protein (G protein), gamma 5
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GTF2A2 general transcription factor IIA, 2, 12kDa
H2AFZ H2A histone family, member Z
HAT1 histone acetyltransferase 1
HAX1 HCLS1 associated protein X-1
HCCS holocytochrome c synthase
HDAC2 histone deacetylase 2
HDDC2 HD domain containing 2
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HSPE1 heat shock 10kDa protein 1
IARS isoleucyl-tRNA synthetase
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFRD1 interferon-related developmental regulator 1
IMMT inner membrane protein, mitochondrial
IPO7 importin 7
KHSRP KH-type splicing regulatory protein
LARP1 La ribonucleoprotein domain family, member 1
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPLA1 lysophospholipase I
MARS methionyl-tRNA synthetase
MCFD2 multiple coagulation factor deficiency 2
MDH1 malate dehydrogenase 1, NAD (soluble)
METAP1 methionyl aminopeptidase 1
MFAP1 microfibrillar-associated protein 1
MLEC malectin
MRPS18B mitochondrial ribosomal protein S18B
MTCP1 mature T-cell proliferation 1
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit
NCBP2 nuclear cap binding protein subunit 2, 20kDa
NCOR2 nuclear receptor corepressor 2
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUDC nudC nuclear distribution protein
NUP62 nucleoporin 62kDa
PDHB pyruvate dehydrogenase (lipoamide) beta
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPT1 palmitoyl-protein thioesterase 1
PRDX3 peroxiredoxin 3
PRDX4 peroxiredoxin 4
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTGES3 prostaglandin E synthase 3 (cytosolic)
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD23A RAD23 homolog A (S. cerevisiae)
RFC4 replication factor C (activator 1) 4, 37kDa
RHEB Ras homolog enriched in brain
RNPEP arginyl aminopeptidase (aminopeptidase B)
RTN4 reticulon 4
RUVBL2 RuvB-like AAA ATPase 2
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCARB1 scavenger receptor class B, member 1
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEC24C SEC24 family member C
SERP1 stress-associated endoplasmic reticulum protein 1
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRPA small nuclear ribonucleoprotein polypeptide A
SOD1 superoxide dismutase 1, soluble
SRSF1 serine/arginine-rich splicing factor 1
SSB Sjogren syndrome antigen B (autoantigen La)
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SSRP1 structure specific recognition protein 1
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STARD7 StAR-related lipid transfer (START) domain containing 7
STK24 serine/threonine kinase 24
TARS threonyl-tRNA synthetase
TCEA1 transcription elongation factor A (SII), 1
TM9SF2 transmembrane 9 superfamily member 2
TM9SF4 transmembrane 9 superfamily protein member 4
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM106C transmembrane protein 106C
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TRAPPC3 trafficking protein particle complex 3
TRIP13 thyroid hormone receptor interactor 13
TUFM Tu translation elongation factor, mitochondrial
UBE2S ubiquitin-conjugating enzyme E2S
VBP1 von Hippel-Lindau binding protein 1
VDAC1 voltage-dependent anion channel 1
VDAC2 voltage-dependent anion channel 2
VDAC3 voltage-dependent anion channel 3
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
XPO7 exportin 7
XPOT exportin, tRNA
YARS tyrosyl-tRNA synthetase
ZWINT ZW10 interacting kinetochore protein